PDB: 112 件ウェブページステータス検索Chemie searchBIRD

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1W93	Crystal Structure of Biotin Carboxylase Domain of Acetyl-Coenzyme A Carboxylase from Saccharomyces cerevisiae 分子名称: ACETYL-COENZYME A CARBOXYLASE 著者 Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. 登録日 2004-10-05 公開日 2005-01-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell, 16, 2004
5CSL	Crystal structure of the 500 kD yeast acetyl-CoA carboxylase holoenzyme dimer 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Acetyl-CoA carboxylase, COENZYME A 著者 Wei, J, Tong, L. 登録日 2015-07-23 公開日 2015-10-28 最終更新日 2022-03-23 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer. Nature, 526, 2015
5KKN	Crystal structure of human ACC2 BC domain in complex with ND-646, the primary amide of ND-630 分子名称: 2-[1-[(2~{R})-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-bis(oxidanylidene)thieno[2,3-d]pyrimidin-3-yl]-2-methyl-propanamide, Acetyl-CoA carboxylase 2 著者 Wang, R, Paul, D, Tong, L. 登録日 2016-06-22 公開日 2016-07-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proc.Natl.Acad.Sci.USA, 113, 2016
1W96	Crystal Structure of Biotin Carboxylase Domain of Acetyl-coenzyme A Carboxylase from Saccharomyces cerevisiae in Complex with Soraphen A 分子名称: ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A 著者 Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. 登録日 2004-10-06 公開日 2005-01-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell, 16, 2004
1BNC	THREE-DIMENSIONAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT OF ACETYL-COA CARBOXYLASE 分子名称: BIOTIN CARBOXYLASE, PHOSPHATE ION 著者 Waldrop, G, Rayment, I, Holden, H.M. 登録日 1994-07-06 公開日 1995-08-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase. Biochemistry, 33, 1994
3N6R	CRYSTAL STRUCTURE OF the holoenzyme of PROPIONYL-COA CARBOXYLASE (PCC) 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-CoA carboxylase, alpha subunit, ... 著者 Huang, C.S, Sadre-Bazzaz, K, Tong, L. 登録日 2010-05-26 公開日 2010-08-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase. Nature, 466, 2010
1ULZ	Crystal structure of the biotin carboxylase subunit of pyruvate carboxylase 分子名称: pyruvate carboxylase n-terminal domain 著者 Kondo, S, Nakajima, Y, Sugio, S, Yong-Biao, J, Sueda, S, Kondo, H. 登録日 2003-09-18 公開日 2004-03-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the biotin carboxylase subunit of pyruvate carboxylase from Aquifex aeolicus at 2.2 A resolution. Acta Crystallogr.,Sect.D, 60, 2004
5CSK	Crystal structure of yeast acetyl-CoA carboxylase, unbiotinylated 分子名称: Acetyl-CoA carboxylase 著者 Wei, J, Tong, L. 登録日 2015-07-23 公開日 2015-10-28 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer. Nature, 526, 2015
2YL2	Crystal structure of human acetyl-CoA carboxylase 1, biotin carboxylase (BC) domain 分子名称: ACETYL-COA CARBOXYLASE 1 著者 Muniz, J.R.C, Froese, D.S, Krysztofinska, E, Vollmar, M, Beltrami, A, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W, Oppermann, U. 登録日 2011-05-31 公開日 2011-06-15 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of Human Acetyl-Coa Carboxylase 1, Biotin Carboxylase (Bc) Domain To be Published
5KS8	Crystal structure of two-subunit pyruvate carboxylase from Methylobacillus flagellatus 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, MANGANESE (II) ION, PYRUVIC ACID, ... 著者 Choi, P.H, Tong, L. 登録日 2016-07-07 公開日 2016-10-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 A distinct holoenzyme organization for two-subunit pyruvate carboxylase. Nat Commun, 7, 2016
1DV1	STRUCTURE OF BIOTIN CARBOXYLASE (APO) 分子名称: BIOTIN CARBOXYLASE, PHOSPHATE ION 著者 Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. 登録日 2000-01-19 公開日 2000-06-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Movement of the biotin carboxylase B-domain as a result of ATP binding. J.Biol.Chem., 275, 2000
3TW6	Structure of Rhizobium etli pyruvate carboxylase T882A with the allosteric activator, acetyl coenzyme-A 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 St Maurice, M, Kumar, S, Lietzan, A.D. 登録日 2011-09-21 公開日 2011-10-19 最終更新日 2011-12-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
2C00	Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form 分子名称: BIOTIN CARBOXYLASE, SULFATE ION 著者 Mochalkin, I. 登録日 2008-03-21 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
3TW7	Structure of Rhizobium etli pyruvate carboxylase T882A crystallized without acetyl coenzyme-A 分子名称: CHLORIDE ION, MAGNESIUM ION, Pyruvate carboxylase protein, ... 著者 St Maurice, M, Kumar, S, Lietzan, A.D. 登録日 2011-09-21 公開日 2011-10-12 最終更新日 2011-12-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
1DV2	The structure of biotin carboxylase, mutant E288K, complexed with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN CARBOXYLASE 著者 Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. 登録日 2000-01-19 公開日 2000-06-09 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Movement of the biotin carboxylase B-domain as a result of ATP binding. J.Biol.Chem., 275, 2000
8F41	3-methylcrotonyl-CoA carboxylase in filament, alpha-subunit centered 分子名称: 3-methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit, ... 著者 Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. 登録日 2022-11-10 公開日 2023-01-11 最終更新日 2023-01-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase. Structure, 31, 2023
8F3D	3-methylcrotonyl-CoA carboxylase in filament, beta-subunit centered 分子名称: 3-methylcrotonyl-CoA carboxylase alpha-subunit, 3-methylcrotonyl-CoA carboxylase beta-subunit, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL 著者 Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. 登録日 2022-11-09 公開日 2023-01-11 最終更新日 2023-01-18 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase. Structure, 31, 2023
6YBP	Propionyl-CoA carboxylase of Methylorubrum extorquens with bound CoA 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... 著者 Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J. 登録日 2020-03-17 公開日 2020-10-28 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (3.48 Å) 主引用文献 A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation Nat Catal, 2021
5MLK	Biotin dependent carboxylase AccA3 dimer from Mycobacterium tuberculosis (Rv3285) 分子名称: Acetyl-COA carboxylase 著者 Bennett, M.D, Hogbom, M. 登録日 2016-12-07 公開日 2017-03-08 最終更新日 2017-05-17 実験手法 X-RAY DIFFRACTION (1.939 Å) 主引用文献 Crystal structure of the essential biotin-dependent carboxylase AccA3 from Mycobacterium tuberculosis. FEBS Open Bio, 7, 2017
6YBQ	Engineered glycolyl-CoA carboxylase (quintuple mutant) with bound CoA 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... 著者 Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J. 登録日 2020-03-17 公開日 2020-10-28 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (1.96 Å) 主引用文献 A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation Nat Catal, 2021
4RCN	Structure and function of a single-chain, multi-domain long-chain acyl-coa carboxylase 分子名称: long-chain acyl-CoA carboxylase 著者 Tran, T.H, Tong, L. 登録日 2014-09-16 公開日 2014-11-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase. Nature, 518, 2015
3BG5	Crystal Structure of Staphylococcus Aureus Pyruvate Carboxylase 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Xiang, S, Tong, L. 登録日 2007-11-26 公開日 2008-02-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat.Struct.Mol.Biol., 15, 2008
4RZQ	Structural Analysis of Substrate, Reaction Intermediate and Product Binding in Haemophilus influenzae Biotin Carboxylase 分子名称: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, methyl (3aS,4S,6aR)-4-(5-methoxy-5-oxopentyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazole-1-carboxylate 著者 Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R, Waldrop, G.L. 登録日 2014-12-23 公開日 2015-06-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
2DZD	Crystal structure of the biotin carboxylase domain of pyruvate carboxylase 分子名称: pyruvate carboxylase 著者 Kondo, S, Nakajima, Y, Sugio, S, Sueda, S, Islam, M.N, Kondo, H. 登録日 2006-09-27 公開日 2007-09-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the biotin carboxylase domain of pyruvate carboxylase from Bacillus thermodenitrificans ACTA CRYSTALLOGR.,SECT.D, 63, 2007
3U9T	Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, free enzyme 分子名称: Methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit 著者 Huang, C.S, Tong, L. 登録日 2011-10-19 公開日 2011-12-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase Nature, 481, 2012

 

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