PDB: 451 件ウェブページステータス検索Chemie searchBIRD

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7U0S	Crystal Structure of FK506-binding protein 1A from Aspergillus fumigatus Bound to Ascomycin 分子名称: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,22R,26aS)-8-ethyl-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone, ACETATE ION, FK506-binding protein 1A, ... 著者 DeBouver, N.D, Fox III, D, Hoy, M.J, Heitman, J, Lorimer, D.D, Horanyi, P.S, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-02-18 公開日 2022-07-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus. Mbio, 13, 2022
7U8D	FKBP12 mutant V55G bound to Rapa*-3Z 分子名称: (3S,5Z,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5-(ethoxyimino)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone, GLYCEROL, Peptidyl-prolyl cis-trans isomerase FKBP1A 著者 Wassarman, D.R, Shokat, K.M. 登録日 2022-03-08 公開日 2022-09-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Tissue-restricted inhibition of mTOR using chemical genetics. Proc.Natl.Acad.Sci.USA, 119, 2022
5HWB	Aspergillus fumigatus FKBP12 apo protein in P212121 space group 分子名称: FK506-binding protein 1A, SULFATE ION 著者 Tonthat, N.K, Schumacher, M.A. 登録日 2016-01-28 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.306 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
5HW6	Candida albicans FKBP12 apo protein in C2 space group 分子名称: ACETATE ION, FK506-binding protein 1 著者 Tonthat, N.K, Schumacher, M.A. 登録日 2016-01-28 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
5HKG	Total chemical synthesis, refolding and crystallographic structure of a fully active immunophilin: calstabin 2 (FKBP12.6). 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Sirigu, S, Huet, T, Bacchi, M, Jullian, M, Fould, B, Ferry, G, Vuillard, L, Chavas, L, Puget, K, Nosjean, O, Boutin, J.A. 登録日 2016-01-14 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6). Protein Sci., 25, 2016
5HT1	Structure of apo C. glabrata FKBP12 分子名称: FK506-binding protein 1 著者 Schumacher, M.A. 登録日 2016-01-26 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.651 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
5HW8	Candida albicans FKBP12 P104G protein bound with FK506 in C2 space group 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506-binding protein 1 著者 Tonthat, N.K, Schumacher, M.A. 登録日 2016-01-28 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
5HUA	Structure of C. glabrata FKBP12-FK506 complex 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506-binding protein 1 著者 Schumacher, M.A. 登録日 2016-01-27 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
5HW7	Candida albicans FKBP12 apo protein in P21212 space group 分子名称: FK506-binding protein 1 著者 Tonthat, N.K, Schumacher, M.A. 登録日 2016-01-28 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.291 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
5HTG	Structure of apo P1 form of Candida albicans FKBP12 分子名称: FK506-binding protein 1 著者 Schumacher, M.A. 登録日 2016-01-26 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
5HWC	Aspergillus fumigatus FKBP12 P90G protein bound with FK506 in P212121 space group 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506-binding protein 1A 著者 Tonthat, N.K, Schumacher, M.A. 登録日 2016-01-29 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
5I98	Structure of apo FKBP12(P104G) from C. albicans 分子名称: FK506-binding protein 1 著者 Schumacher, M.A. 登録日 2016-02-19 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
5I7P	Crystal structure of Fkbp12-IF(SlyD), a chimeric protein of human Fkbp12 and the insert in flap domain of Ecoli SlyD 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1A,FKBP-type peptidyl-prolyl cis-trans isomerase SlyD,Peptidyl-prolyl cis-trans isomerase FKBP1A 著者 Jakob, R.P, Knappe, T.A, Dobbek, H, Schmid, F.X. 登録日 2016-02-18 公開日 2017-03-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 Structural and Functional Analysis of Chaperone Domain Insertion in Fkbp12 To Be Published
5I7Q	Crystal structure of Fkbp12-IF(SlpA), a chimeric protein of human Fkbp12 and the insert in flap domain of Ecoli SlpA 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1A,FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase,Peptidyl-prolyl cis-trans isomerase FKBP1A 著者 Jakob, R.P, Dobbek, H, Schmid, F.X. 登録日 2016-02-18 公開日 2017-03-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Functional Analysis of Chaperone Domain Insertion in Fkbp12 To Be Published
5J6E	Structure of disulfide crosslinked A. fumigatus FKBP12(V91C) 分子名称: FK506-binding protein 1A 著者 Schumacher, M. 登録日 2016-04-04 公開日 2016-09-14 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
3IHZ	Crystal structure of the FK506 binding domain of Plasmodium vivax FKBP35 in complex with FK506 分子名称: 70 kDa peptidylprolyl isomerase, putative, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN 著者 Qureshi, I.A, Alag, R, Yoon, H.S, Lescar, J. 登録日 2009-07-31 公開日 2010-06-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35 Protein Sci., 19, 2010
3JYM	Crystal Structure of the 3 FKBP domains of wheat FKBP73 分子名称: FK506-binding protein (FKBP) from wheat 著者 Dym, O, Breiman, A, Israel Structural Proteomics Center (ISPC) 登録日 2009-09-22 公開日 2010-06-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Crystal structure of the three FK506 binding protein domains of wheat FKBP73: evidence for a unique wFK73_2 domain J.STRUCT.FUNCT.GENOM., 11, 2010
4IPX	Analyzing the visible conformational substates of the FK506 binding protein FKBP12 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Peptidyl-prolyl cis-trans isomerase FKBP1A 著者 Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G. 登録日 2013-01-10 公開日 2013-06-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Analysing the visible conformational substates of the FK506-binding protein FKBP12. Biochem.J., 453, 2013
4IQ2	P21 crystal form of FKBP12.6 分子名称: MALONIC ACID, Peptidyl-prolyl cis-trans isomerase FKBP1B 著者 Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G. 登録日 2013-01-10 公開日 2014-01-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6. Acta Crystallogr.,Sect.D, 70, 2014
3JXV	Crystal Structure of the 3 FKBP domains of wheat FKBP73 分子名称: 70 kDa peptidyl-prolyl isomerase 著者 Dym, O, Breiman, A, Israel Structural Proteomics Center (ISPC) 登録日 2009-09-21 公開日 2010-06-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Crystal structure of the three FK506 binding protein domains of wheat FKBP73: evidence for a unique wFK73_2 domain. J Struct Funct Genomics, 11, 2010
4IQC	P3121 crystal form of FKBP12.6 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B 著者 Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G. 登録日 2013-01-11 公開日 2014-01-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6. Acta Crystallogr.,Sect.D, 70, 2014
4ITZ	Crystal structure of the FK506 binding domain of Plasmodium vivax FKBP35 in complex with a tetrapeptide substrate 分子名称: 70 kDa peptidylprolyl isomerase, SULFATE ION, substrate peptide 著者 Sreekanth, R, Yoon, H.S. 登録日 2013-01-19 公開日 2013-03-20 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural insights into substrate binding by PvFKBP35, a peptidylprolyl cis-trans isomerase from the human malarial parasite Plasmodium vivax. Eukaryot Cell, 12, 2013
4J4O	Crystal structure of FK506 binding domain of plasmodium VIVAX FKBP35 in complex with D44 分子名称: 70 kDa peptidylprolyl isomerase, putative, GLYCEROL, ... 著者 Sreekanth, R, Harikishore, A, Yoon, H.S. 登録日 2013-02-07 公開日 2013-09-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent. Sci Rep, 3, 2013
4J4N	Crystal structure of FK506 binding domain of plasmodium falciparum FKBP35 in complex with D44 分子名称: FK506-binding protein (FKBP)-type peptidyl-propyl isomerase, N-(2-ethylphenyl)-2-(3H-imidazo[4,5-b]pyridin-2-ylsulfanyl)acetamide 著者 Sreekanth, R, Harikishore, A, Yoon, H.S. 登録日 2013-02-07 公開日 2013-09-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent. Sci Rep, 3, 2013
4JFJ	Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with compound (1S,6R)-10-(1,3-benzothiazol-6-ylsulfonyl)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-3,10-diazabicyclo[4.3.1]decan-2-one 分子名称: (1S,6R)-10-(1,3-benzothiazol-6-ylsulfonyl)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-3,10-diazabicyclo[4.3.1]decan-2-one, Peptidyl-prolyl cis-trans isomerase FKBP5 著者 Wang, Y, Kirschner, A, Fabian, A, Gopalakrishnan, R, Kress, C, Hoogeland, B, Koch, U, Kozany, C, Bracher, A, Hausch, F. 登録日 2013-02-28 公開日 2013-08-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control. J.Med.Chem., 56, 2013

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