PDB: 608 resultsInfo pagesStatus searchChemie searchBIRD

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7OQJ	Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ162 Descriptor: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), CHLORIDE ION, ... Authors: Centorrino, F, Ottmann, C. Deposit date: 2021-06-03 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQG	Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ136 Descriptor: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), BETA-MERCAPTOETHANOL, ... Authors: Centorrino, F, Ottmann, C. Deposit date: 2021-06-03 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQ9	Ternary complex of 14-3-3 sigma, Pin1pS72 phosphopeptide, and WQ136 Descriptor: 14-3-3 protein sigma, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... Authors: Centorrino, F, Ottmann, C. Deposit date: 2021-06-02 Release date: 2022-08-10 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQA	Ternary complex of 14-3-3 sigma, Pin1pS72 phosphopeptide, and WQ162 Descriptor: 14-3-3 protein sigma, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... Authors: Centorrino, F, Ottmann, C. Deposit date: 2021-06-02 Release date: 2022-08-10 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQ7	Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ162 Descriptor: 14-3-3 protein sigma, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... Authors: Centorrino, F, Ottmann, C. Deposit date: 2021-06-02 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OQ8	Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ178 Descriptor: 14-3-3 protein sigma, CHLORIDE ION, Estrogen receptor, ... Authors: Centorrino, F, Ottmann, C. Deposit date: 2021-06-02 Release date: 2022-06-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.43 Å) Cite: A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OPW	Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ136 Descriptor: 14-3-3 protein sigma, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... Authors: Centorrino, F, Ottmann, C. Deposit date: 2021-06-01 Release date: 2022-06-08 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.81 Å) Cite: A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7EXE	Crystal structure of mouse 14-3-3zeta in complex with doubly phosphorylated ADAM22 peptide Descriptor: 14-3-3 protein zeta/delta, Disintegrin and metalloproteinase domain-containing protein 22 Authors: Yan, L, Okatsu, K, Fukai, S. Deposit date: 2021-05-27 Release date: 2021-11-24 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.75 Å) Cite: LGI1-ADAM22 levels regulate seizure thresholds through 14-3-3 in mice Cell Rep, 2021
7OBY	Crystal structure of 14-3-3 sigma in complex with SSBP4 phosphopeptide and stabilizer Fusicoccin-A Descriptor: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-24 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OBX	Crystal structure of 14-3-3 sigma in complex with SSBP4 phosphopeptide Descriptor: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-23 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OBS	Crystal structure of 14-3-3 sigma in complex with RIPK2 phosphopeptide Descriptor: 14-3-3 protein sigma, CALCIUM ION, MAGNESIUM ION, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-23 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OBT	Crystal structure of 14-3-3 sigma in complex with RIPK2 phosphopeptide and stabilizer Fusicoccin-A Descriptor: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-23 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OBK	Crystal structure of 14-3-3 sigma in complex with PKR phosphopeptide Descriptor: 14-3-3 protein sigma, MAGNESIUM ION, PKR phosphopeptide Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-22 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OBG	Crystal structure of 14-3-3 sigma in complex with NPM1 phosphopeptide Descriptor: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-22 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OBL	Crystal structure of 14-3-3 sigma in complex with PKR phosphopeptide and stabilizer Fusicoccin-A Descriptor: 14-3-3 protein sigma, FUSICOCCIN, MAGNESIUM ION, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-22 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OBH	Crystal structure of 14-3-3 sigma in complex with NPM1 phosphopeptide and stabilizer Fusicoccin-A Descriptor: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-22 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OB5	Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide Descriptor: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-21 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OB8	Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide and stabilizer Fusicoccin-A Descriptor: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-21 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OBC	Crystal structure of 14-3-3 sigma in complex with Phosphorylated and Farnesylated Rnd3 peptide Descriptor: 14-3-3 protein sigma, CHLORIDE ION, FARNESYL, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-21 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7OBD	Crystal structure of 14-3-3 sigma in complex with Phosphorylated and Farnesylated Rnd3 peptide and stabilizer Fusicoccin-A Descriptor: 14-3-3 protein sigma, CHLORIDE ION, FARNESYL, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-21 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
7O6M	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-097 Descriptor: (5-methanoyl-2-nitro-phenyl) 1-methylpyrazole-4-sulfonate, 14-3-3 protein sigma, CALCIUM ION, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-04-11 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O6J	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-083 Descriptor: (5-methanoyl-2-nitro-phenyl) 2-(3-methoxyphenyl)ethanoate, 14-3-3 protein sigma, CHLORIDE ION, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-04-11 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O6K	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-080 Descriptor: (5-methanoyl-2-nitro-phenyl) 3-chloranylbenzoate, 14-3-3 protein sigma, CALCIUM ION, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-04-11 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O6F	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-178 Descriptor: 14-3-3 protein sigma, 4-[4-(2-hydroxyethyl)piperidin-1-yl]carbonylbenzaldehyde, CALCIUM ION, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-04-11 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O6G	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-176 Descriptor: 14-3-3 protein sigma, 4-[(3~{R})-3-oxidanylpiperidin-1-yl]carbonylbenzaldehyde, CALCIUM ION, ... Authors: Wolter, M, Ottmann, C. Deposit date: 2021-04-11 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021

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