PDB: 1333 件ウェブページステータス検索Chemie searchBIRD

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4WW6	Crystal structure of human carbonic anhydrase isozyme II with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide 分子名称: 2,3,5,6-tetrafluoro-4-(propylsulfanyl)benzenesulfonamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BICINE, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-11-10 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.06 Å) 主引用文献 Intrinsic thermodynamics of 4-substituted-2,3,5,6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry. Biophys.Chem., 205, 2015
4WR7	Crystal structure of human carbonic anhydrase isozyme I with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide. 分子名称: 1,2-ETHANEDIOL, 2,3,5,6-tetrafluoro-4-(propylsulfanyl)benzenesulfonamide, ACETATE ION, ... 著者 Manakova, E, Smirnov, A, Grazulis, S. 登録日 2014-10-23 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Intrinsic thermodynamics of 4-substituted-2,3,5,6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry. Biophys.Chem., 205, 2015
4WUQ	Crystal structure of human carbonic anhydrase isozyme I with 2,3,5,6-Tetrafluoro-4-piperidin-1-ylbenzenesulfonamide 分子名称: 2,3,5,6-tetrafluoro-4-(piperidin-1-yl)benzenesulfonamide, Carbonic anhydrase 1, DI(HYDROXYETHYL)ETHER, ... 著者 Manakova, E, Smirnov, A, Grazulis, S. 登録日 2014-11-03 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Intrinsic thermodynamics of 4-substituted-2,3,5,6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry. Biophys.Chem., 205, 2015
2Q1B	Carbonic Anhydrase II in Complex with Saccharin 分子名称: 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, BENZOIC ACID, Carbonic anhydrase 2, ... 著者 Klebe, G, Heine, A, Koehler, K. 登録日 2007-05-24 公開日 2007-09-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Saccharin Inhibits Carbonic Anhydrases: Possible Explanation for its Unpleasant Metallic Aftertaste. Angew.Chem.Int.Ed.Engl., 46, 2007
2POU	The crystal structure of the human carbonic anhydrase II in complex with 4,5-dichloro-benzene-1,3-disulfonamide 分子名称: 4,5-DICHLOROBENZENE-1,3-DISULFONAMIDE, Carbonic anhydrase 2, ZINC ION 著者 Alterio, V, De Simone, G. 登録日 2007-04-27 公開日 2007-07-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides-Solution and crystallographic studies. Bioorg.Med.Chem.Lett., 17, 2007
4WL4	Crystal structure of human carbonic anhydrase II in complex with the 6-hydroxy-chromene-2-thione inhibitor 分子名称: 1,2-ETHANEDIOL, 6-hydroxy-2H-chromene-2-thione, Carbonic anhydrase 2, ... 著者 Ferraroni, M. 登録日 2014-10-06 公開日 2015-10-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 New classes of carbonic anhydrase inhibitors to be published
4WW8	Crystal structure of human carbonic anhydrase isozyme XII with 4-Propylthiobenzenesulfonamide 分子名称: 1,2-ETHANEDIOL, 4-(propylsulfanyl)benzenesulfonamide, Carbonic anhydrase 12, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-11-10 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Intrinsic thermodynamics of 4-substituted-2,3,5,6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry. Biophys.Chem., 205, 2015
4WUP	Crystal structure of human carbonic anhydrase isozyme I with 4-[(2-Hydroxyethyl)thio]benzenesulfonamide 分子名称: 4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide, ACETATE ION, Carbonic anhydrase 1, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-11-03 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Intrinsic thermodynamics of 4-substituted-2,3,5,6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry. Biophys.Chem., 205, 2015
4X5S	The crystal structure of an alpha carbonic anhydrase from the extremophilic bacterium Sulfurihydrogenibium azorense. 分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase (Carbonate dehydratase), ... 著者 De Simone, G, Alterio, V, Di Fiore, A. 登録日 2014-12-05 公開日 2015-05-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense. Bioorg.Med.Chem.Lett., 25, 2015
2Q1Q	Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and X-Ray crystallographic studies 分子名称: Carbonic anhydrase 2, MERCURY (II) ION, SULTHIAME, ... 著者 Temperini, C, Innocenti, A, Mastrolorenzo, A, Scozzafava, A, Supuran, C.T. 登録日 2007-05-25 公開日 2007-09-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: Kinetic and X-ray crystallographic studies. Bioorg.Med.Chem.Lett., 17, 2007
2Q38	Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom 分子名称: 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, BENZOIC ACID, Carbonic anhydrase 2, ... 著者 Schulze Wischeler, J, Heine, A, Klebe, G. 登録日 2007-05-30 公開日 2007-10-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Saccharin Inhibits Carbonic Anhydrases: Possible Explanation for its Unpleasant Metallic Aftertaste. Angew.Chem.Int.Ed.Engl., 46, 2007
2POW	The crystal structure of the human carbonic anhydrase II in complex with 4-amino-6-trifluoromethyl-benzene-1,3-disulfonamide 分子名称: 4-AMINO-6-(TRIFLUOROMETHYL)BENZENE-1,3-DISULFONAMIDE, Carbonic anhydrase 2, ZINC ION 著者 Alterio, V, De Simone, G. 登録日 2007-04-27 公開日 2007-07-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides-Solution and crystallographic studies. Bioorg.Med.Chem.Lett., 17, 2007
4XIX	Carbonic anhydrase Cah3 from Chlamydomonas reinhardtii in complex with phosphate. 分子名称: Carbonic anhydrase, alpha type, DIHYDROGENPHOSPHATE ION, ... 著者 Hainzl, T, Grundstrom, C, Benlloch, R, Shevela, D, Shutova, T, Messinger, J, Samuelsson, G, Sauer-Eriksson, A.E. 登録日 2015-01-08 公開日 2015-02-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure and Functional Characterization of Photosystem II-Associated Carbonic Anhydrase CAH3 in Chlamydomonas reinhardtii. Plant Physiol., 167, 2015
4XZ5	Structure of the thermostable alpha-Carbonic Anydrase from Thiomicrospira crunogena XCL-2 gammaproteobacterium 分子名称: BICARBONATE ION, Carbonic anhydrase, alpha family, ... 著者 Mahon, B.P, Diaz-Torres, N.A, Pinard, M.A, McKenna, R. 登録日 2015-02-03 公開日 2015-07-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.596 Å) 主引用文献 Structural and biophysical characterization of the alpha-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2: insights into engineering thermostable enzymes for CO2 sequestration. Acta Crystallogr.,Sect.D, 71, 2015
2POV	The crystal structure of the human carbonic anhydrase II in complex with 4-amino-6-chloro-benzene-1,3-disulfonamide 分子名称: 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE, Carbonic anhydrase 2, ZINC ION 著者 Alterio, V, De Simone, G. 登録日 2007-04-27 公開日 2007-07-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides-Solution and crystallographic studies. Bioorg.Med.Chem.Lett., 17, 2007
4XIW	Carbonic anhydrase Cah3 from Chlamydomonas reinhardtii in complex with acetazolamide 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase, alpha type, ... 著者 Hainzl, T, Grundstrom, C, Benlloch, R, Shevela, D, Shutova, T, Messinger, J, Samuelsson, G, Sauer-Eriksson, A.E. 登録日 2015-01-07 公開日 2015-02-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure and Functional Characterization of Photosystem II-Associated Carbonic Anhydrase CAH3 in Chlamydomonas reinhardtii. Plant Physiol., 167, 2015
4XFW	Crystal structure of the monoclinic form of alpha-carbonic anhydrase from the human pathogen Helicobacter pylori 分子名称: ACETIC ACID, Alpha-carbonic anhydrase, CHLORIDE ION, ... 著者 Compostella, M.E, Vallese, F, Berto, P, Zanotti, G. 登録日 2014-12-29 公開日 2015-08-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.517 Å) 主引用文献 Structure of alpha-carbonic anhydrase from the human pathogen Helicobacter pylori. Acta Crystallogr.,Sect.F, 71, 2015
4Y0J	H/D exchanged human carbonic anhydrase II pH 6 room temperature neutron crystal structure. 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Fisher, S.Z. 登録日 2015-02-06 公開日 2015-04-22 最終更新日 2024-01-10 実験手法 NEUTRON DIFFRACTION (2 Å) 主引用文献 Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer. Proc.Natl.Acad.Sci.USA, 112, 2015
4XE1	Human carbonic anhydrase II in complex with 6-SULFAMOYL-SACCHARIN 分子名称: 3-oxo-2,3-dihydro-1,2-benzothiazole-6-sulfonamide 1,1-dioxide, 4-(HYDROXYMERCURY)BENZOIC ACID, Carbonic anhydrase 2, ... 著者 Alterio, V, De Simone, G. 登録日 2014-12-21 公開日 2015-03-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor. Org.Biomol.Chem., 13, 2015
2QO8	Crystal structure of the complex of hcaii with an indane-sulfonamide inhibitor 分子名称: Carbonic anhydrase 2, GLYCEROL, MERCURIBENZOIC ACID, ... 著者 D'Ambrosio, K, De Simone, G. 登録日 2007-07-20 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Carbonic Anhydrase Inhibitors: Binding of Indanesulfonamides to the Human Isoform II. Chemmedchem, 3, 2007
2QOA	Crystal structure of the complex of hcaii with an indane-sulfonamide inhibitor 分子名称: CHLORIDE ION, Carbonic anhydrase 2, GLYCEROL, ... 著者 D'Ambrosio, K, De Simone, G. 登録日 2007-07-20 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Carbonic Anhydrase Inhibitors: Binding of Indanesulfonamides to the Human Isoform II. Chemmedchem, 3, 2007
2QP6	The crystal structure of the complex of hcaII with a bioreductive antitumor derivative 分子名称: 2-chloro-5-nitrobenzenesulfonamide, CHLORIDE ION, Carbonic anhydrase 2, ... 著者 D'Ambrosio, K, De Simone, G. 登録日 2007-07-23 公開日 2008-06-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Carbonic Anhydrase Inhibitors: Bioreductive Nitro-Containing Sulfonamides with Selectivity for Targeting the Tumor Associated Isoforms IX and XII. J.Med.Chem., 51, 2008
4YGK	NaSCN--Interactions between Hofmeister Anions and the Binding Pocket of a Protein 分子名称: Carbonic anhydrase 2, HYDROXIDE ION, THIOCYANATE ION, ... 著者 Fox, J.M, Kang, K, Sherman, W, Heroux, A, Sastry, G.M, Baghbanzadeh, M, Lockett, M.R, Whitesides, G.M. 登録日 2015-02-26 公開日 2015-03-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Interactions between Hofmeister Anions and the Binding Pocket of a Protein. J.Am.Chem.Soc., 137, 2015
4YGF	Crystal structure of the complex of Helicobacter pylori alpha-Carbonic Anhydrase with acetazolamide 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Alpha-carbonic anhydrase, CHLORIDE ION, ... 著者 Roujeinikova, A, Modak, J.K. 登録日 2015-02-26 公開日 2015-07-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for the Inhibition of Helicobacter pylori alpha-Carbonic Anhydrase by Sulfonamides. Plos One, 10, 2015
4YGJ	NaBr--Interactions between Hofmeister Anions and the Binding Pocket of a Protein 分子名称: BROMIDE ION, Carbonic anhydrase 2, ZINC ION 著者 Fox, J.M, Kang, K, Sherman, W, Heroux, A, Sastry, G.M, Baghbanzadeh, M, Lockett, M.R, Whitesides, G.M. 登録日 2015-02-26 公開日 2015-03-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Interactions between Hofmeister Anions and the Binding Pocket of a Protein. J.Am.Chem.Soc., 137, 2015

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