7FQ2
 
 | | DHFR:NADP+:FOL complex at 300 K (multi-crystal) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 300 K
To Be Published
|
|
7FQ1
 | | DHFR:NADP+:FOL complex at 300 K (crystal 5) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 300 K
To Be Published
|
|
7FQ0
 | | DHFR:NADP+:FOL complex at 300 K (crystal 4) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 300 K
To Be Published
|
|
7FPZ
 | | DHFR:NADP+:FOL complex at 300 K (crystal 3) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 300 K
To Be Published
|
|
7FPY
 | | DHFR:NADP+:FOL complex at 300 K (crystal 2) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 300 K
To Be Published
|
|
7FPX
 | | DHFR:NADP+:FOL complex at 300 K (crystal 1) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 300 K
To Be Published
|
|
7FPW
 | | DHFR:NADP+:FOL complex at 290 K (multi-crystal) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 290 K
To Be Published
|
|
7FPV
 | | DHFR:NADP+:FOL complex at 290 K (crystal 5) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 290 K
To Be Published
|
|
7FPU
 | | DHFR:NADP+:FOL complex at 290 K (crystal 4) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 290 K
To Be Published
|
|
7FPT
 | | DHFR:NADP+:FOL complex at 290 K (crystal 3) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 290 K
To Be Published
|
|
7FPS
 | | DHFR:NADP+:FOL complex at 290 K (crystal 2) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 290 K
To Be Published
|
|
7FPR
 | | DHFR:NADP+:FOL complex at 290 K (crystal 1) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-10 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 290 K
To Be Published
|
|
7FPQ
 | | DHFR:NADP+:FOL complex at 280 K (multi-crystal) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-09 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 280 K
To Be Published
|
|
7FPP
 | | DHFR:NADP+:FOL complex at 280 K (crystal 5) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-09 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 280 K
To Be Published
|
|
7FPO
 | | DHFR:NADP+:FOL complex at 280 K (crystal 4) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-09 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 280 K
To Be Published
|
|
7FPN
 | | DHFR:NADP+:FOL complex at 280 K (crystal 3) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-09 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 280 K
To Be Published
|
|
7FPM
 | | DHFR:NADP+:FOL complex at 280 K (crystal 2) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-09 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 280 K
To Be Published
|
|
7FPL
 | | DHFR:NADP+:FOL complex at 280 K (crystal 1) | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | | 登録日 | 2022-09-09 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | DHFR:NADP+:FOL complex at 280 K
To Be Published
|
|
7FGY
 | | Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with P40, NADPH and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(3-chlorophenyl)-6-[2-(3-phenoxypropoxy)ethyl]pyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | | 著者 | Vanichtanankul, J, Yoomuang, A, Taweechai, S, Saeyang, T, Yuvaniyama, J, Tarnchompoo, B, Yuthavong, Y, Kamchonwongpaisan, S. | | 登録日 | 2021-07-28 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase.
Acs Chem.Biol., 17, 2022
|
|
7FGX
 | | Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with P39, NADPH and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 6-hexyl-5-phenyl-pyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | | 著者 | Vanichtanankul, J, Yoomuang, A, Taweechai, S, Saeyang, T, Yuvaniyama, J, Tarnchompoo, B, Yuthavong, Y, Kamchonwongpaisan, S. | | 登録日 | 2021-07-28 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase.
Acs Chem.Biol., 17, 2022
|
|
7FGW
 | | Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with pyrimethamine, NADPH and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, BENZAMIDINE, ... | | 著者 | Vanichtanankul, J, Yoomuang, A, Taweechai, S, Saeyang, T, Yuvaniyama, Y, Tarnchompoo, B, Yuthavong, Y, Kamchonwongpaisan, S. | | 登録日 | 2021-07-28 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase.
Acs Chem.Biol., 17, 2022
|
|
7F3Z
 | | Double mutant Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-K1, C59R+S108N) complexed with Trimethoprim (TOP), NADPH and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, GLYCEROL, ... | | 著者 | Vanichtanankul, J, Tanramluk, D, Chitnumsub, P, Yuvaniyama, J, Yuthavong, Y. | | 登録日 | 2021-06-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | MANORAA: A machine learning platform to guide protein-ligand design by anchors and influential distances.
Structure, 30, 2022
|
|
7F3Y
 | | Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with methotrexate (MTX), NADPH and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, GLYCEROL, ... | | 著者 | Vanichtanankul, J, Tanramluk, D, Yuvaniyama, J, Yuthavong, Y. | | 登録日 | 2021-06-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.252 Å) | | 主引用文献 | MANORAA: A machine learning platform to guide protein-ligand design by anchors and influential distances.
Structure, 30, 2022
|
|
7F3B
 | | cocrystallization of Escherichia coli dihydrofolate reductase (DHFR) and its pyrrolo[3,2-f]quinazoline inhibitor. | | 分子名称: | 7-[(2-fluorophenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine, Dihydrofolate reductase, GLYCEROL | | 著者 | Wang, H, You, X.F, Yang, X.Y, Li, Y, Hong, W. | | 登録日 | 2021-06-16 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates.
Eur.J.Med.Chem., 228, 2022
|
|
7ESE
 | | The Crystal Structure of human DHFR from Biortus | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, F, Cheng, W, Xu, C, Qi, J, Bao, X, Miao, Q. | | 登録日 | 2021-05-10 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Crystal Structure of human DHFR from Biortus
To Be Published
|
|
