PDB: 198 件ウェブページステータス検索Chemie searchBIRD

---

6CXW	Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function 分子名称: Synaptotagmin 1 C2A beta4 chimera 著者 Sutton, R.B. 登録日 2018-04-04 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.832 Å) 主引用文献 Engineering a C2-domain to bind PIP2 To Be Published
5T0R	Synaptotagmin 1 C2A domain, cadmium-bound 分子名称: CADMIUM ION, Synaptotagmin-1 著者 Taylor, A.B, Hart, P.J, Igumenova, T.I. 登録日 2016-08-16 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Non-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions. Biochemistry, 56, 2017
5T0S	Synaptotagmin 1 C2B domain, cadmium-bound 分子名称: CADMIUM ION, SODIUM ION, Synaptotagmin-1 著者 Taylor, A.B, Hart, P.J, Igumenova, T.I. 登録日 2016-08-16 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Non-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions. Biochemistry, 56, 2017
6EEL	Crystal Structure of Myoferlin C2A with divalent cation 分子名称: Myoferlin, STRONTIUM ION 著者 Sutton, R.B, Harsini, F.M, Rice, A.M. 登録日 2018-08-14 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structural Basis for the Distinct Membrane Binding Activity of the Homologous C2A Domains of Myoferlin and Dysferlin. J.Mol.Biol., 431, 2019
5UG6	Perforin C2 Domain - T431D 分子名称: IODIDE ION, Perforin-1 著者 Law, R.H.P, Conroy, P.J, Voskoboinik, I, Whisstock, J.C. 登録日 2017-01-07 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death Differ., 25, 2018
6EI6	CC2D1B coordinates ESRCT-III activity during the mitotic reformation of the nuclear envelope 分子名称: Coiled-coil and C2 domain-containing protein 1-like, DI(HYDROXYETHYL)ETHER, SULFATE ION 著者 Ventimiglia, L.N, Cuesta-Geijo, M.A, Martinelli, N, Caballe, A, Macheboeuf, P, Miguet, N, Parnham, I.M, Olmos, Y, Carlton, J.G, Weissehorn, W, martin-Serrano, J. 登録日 2017-09-18 公開日 2018-10-10 最終更新日 2018-12-19 実験手法 X-RAY DIFFRACTION (2.461 Å) 主引用文献 CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope. Dev. Cell, 47, 2018
6EWP	Mus musculus CEP120 third C2 domain (C2C) 分子名称: Centrosomal protein of 120 kDa, HEXAETHYLENE GLYCOL 著者 van Breugel, M, al-Jassar, C. 登録日 2017-11-06 公開日 2018-05-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis. Cell Rep, 23, 2018
5UG7	Calcium bound Perforin C2 Domain - T431D 分子名称: CALCIUM ION, Perforin-1 著者 Law, R.H.P, Conroy, P.J, Voskoboinik, I, Whisstock, J.C. 登録日 2017-01-07 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death Differ., 25, 2018
6FB4	human KIBRA C2 domain mutant C771A 分子名称: GLYCEROL, PHOSPHATE ION, Protein KIBRA 著者 Crennell, S.J, Posner, M.G, Bagby, S. 登録日 2017-12-18 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.415631 Å) 主引用文献 Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
6FJC	Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 3,4,5-trisphosphate 分子名称: (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, GLYCEROL, Protein KIBRA, ... 著者 Crennell, S.J, Posner, M.G, Bagby, S. 登録日 2018-01-22 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.598 Å) 主引用文献 Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
6FJD	Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 4,5-bisphosphate 分子名称: (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, GLYCEROL, Protein KIBRA, ... 著者 Crennell, S.J, Posner, M.G, Bagby, S. 登録日 2018-01-22 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.898 Å) 主引用文献 Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
6FD0	Human KIBRA C2 domain mutant M734I S735A 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Protein KIBRA 著者 Crennell, S.J, Posner, M.G, Bagby, S. 登録日 2017-12-21 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.64215851 Å) 主引用文献 Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
6FLK	Crystal structure of Cep120 C2C domain 分子名称: Cep120 著者 Sharma, A, Gerard, S.F, Olieric, N, Steinmetz, M.O. 登録日 2018-01-26 公開日 2018-02-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Cep120 promotes microtubule formation through a unique tubulin binding C2 domain. J. Struct. Biol., 203, 2018
6FLJ	Crystal structure of Cep120 C2A_K76A mutant 分子名称: Centrosomal protein of 120 kDa 著者 Sharma, A, Gerard, S.F, Olieric, N, Steinmetz, M.O. 登録日 2018-01-26 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Cep120 promotes microtubule formation through a unique tubulin binding C2 domain. J. Struct. Biol., 203, 2018
5VFF	Synaptotagmin 1 C2B domain, lead-bound (low occupancy) 分子名称: LEAD (II) ION, Synaptotagmin-1 著者 Taylor, A.B, Hart, P.J, Igumenova, T.I. 登録日 2017-04-07 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.413 Å) 主引用文献 High affinity interactions of Pb2+with synaptotagmin I. Metallomics, 10, 2018
5VFG	Synaptotagmin 1 C2B domain, lead-bound (high occupancy) 分子名称: LEAD (II) ION, Synaptotagmin-1 著者 Taylor, A.B, Hart, P.J, Igumenova, T.I. 登録日 2017-04-07 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 High affinity interactions of Pb2+with synaptotagmin I. Metallomics, 10, 2018
5VFE	Synaptotagmin 1 C2A domain, lead-bound 分子名称: LEAD (II) ION, SULFATE ION, Synaptotagmin-1 著者 Taylor, A.B, Hart, P.J, Igumenova, T.I. 登録日 2017-04-07 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 High affinity interactions of Pb2+with synaptotagmin I. Metallomics, 10, 2018
5W4S	Solution structure of C2 domain from protein kinase C alpha in ternary complex with calcium and V5-pHM peptide 分子名称: CALCIUM ION, Protein kinase C alpha type, V5-pHM peptide 著者 Yang, Y, Igumenova, T.I. 登録日 2017-06-12 公開日 2018-04-25 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural Basis of Protein Kinase C alpha Regulation by the C-Terminal Tail. Biophys. J., 114, 2018
2K3H	Structural determinants for Ca2+ and PIP2 binding by the C2A domain of rabphilin-3A 分子名称: CALCIUM ION, Rabphilin-3A 著者 Coudevylle, N, Montaville, P, Leonov, A, Zweckstetter, M, Becker, S. 登録日 2008-05-08 公開日 2008-10-21 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structural Determinants for Ca2+ and Phosphatidylinositol 4,5-Bisphosphate Binding by the C2A Domain of Rabphilin-3A. J.Biol.Chem., 283, 2008
2K45	C2A domain of synaptototagmin I solution structure in the FGF-1-C2A binary complex: key component in the fibroblast growthfactor non-classical pathway 分子名称: Synaptotagmin-1 著者 Mohan, S.K, Yu, C. 登録日 2008-05-28 公開日 2009-06-02 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release To be Published
2JQZ	Solution Structure of the C2 domain of human Smurf2 分子名称: E3 ubiquitin-protein ligase SMURF2 著者 Wiesner, S, Ogunjimi, A.A, Wang, H, Rotin, D, Sicheri, F, Wrana, J.L, Forman-Kay, J.D. 登録日 2007-06-15 公開日 2007-09-11 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain Cell(Cambridge,Mass.), 130, 2007
2LHA	Solution structure of C2B with IP6 分子名称: INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-1 著者 Joung, M, Mohan, S.K, Yu, C. 登録日 2011-08-08 公開日 2012-05-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Molecular Level Interaction of Inositol Hexaphosphate with the C2B Domain of Human Synaptotagmin I Biochemistry, 2012
2NQ3	Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase 分子名称: CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2006-10-30 公開日 2006-11-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase To be Published
2NCE	Solution Structure of Ca2+-bound C2 domain from Protein Kinase C alpha in the form of complex with V5-pHM peptide 分子名称: CALCIUM ION, Protein kinase C alpha type 著者 Yang, Y, Igumenova, T.I. 登録日 2016-03-28 公開日 2017-03-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Ca2+-sensing domain contributes to auto-inhibition of protein kinase Calpha through interactions with C-terminal tail To be Published
2NSQ	Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein 分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2006-11-06 公開日 2006-12-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein To be Published

<12345678>