PDB: 117 件ウェブページステータス検索Chemie searchBIRD

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1SKM	HhaI methyltransferase in complex with DNA containing an abasic south carbocyclic sugar at its target site 分子名称: 5'-D(*T*GP*TP*CP*AP*GP*(HCX)P*GP*CP*AP*TP*GP*G)-3', 5'-D(*TP*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', Modification methylase HhaI, ... 著者 Horton, J.R, Ratner, G, Banavali, N, Huang, N, Marquez, V.E, MacKerell, A.D, Cheng, X. 登録日 2004-03-05 公開日 2004-08-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferase Nucleic Acids Res., 32, 2004
1SVU	Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions 分子名称: Modification methylase HhaI, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... 著者 Dong, A, Zhou, L, Zhang, X, Stickel, S, Roberts, R.J, Cheng, X. 登録日 2004-03-30 公開日 2004-06-29 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions Biol.Chem., 385, 2004
1M0E	ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASE 分子名称: 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(Z)P*GP*CP*AP*TP*GP*G)-3', Modification methylase HhaI, ... 著者 Zhou, L, Cheng, X, Connolly, B.A, Dickman, M.J, Hurd, P.J, Hornby, D.P. 登録日 2002-06-12 公開日 2002-09-18 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASES J.MOL.BIOL., 321, 2002
1G55	Structure of human DNMT2, an enigmatic DNA methyltransferase homologue 分子名称: BETA-MERCAPTOETHANOL, DNA CYTOSINE METHYLTRANSFERASE DNMT2, GLYCEROL, ... 著者 Dong, A, Yoder, J.A, Zhang, X, Zhou, L, Bestor, T.H, Cheng, X. 登録日 2000-10-30 公開日 2001-01-17 最終更新日 2018-06-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA. Nucleic Acids Res., 29, 2001
1FJX	STRUCTURE OF TERNARY COMPLEX OF HHAI METHYLTRANSFERASE MUTANT (T250G) IN COMPLEX WITH DNA AND ADOHCY 分子名称: DNA (5'-D(*TP*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), HHAI DNA METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Vilkaitis, G, Dong, A, Weinhold, E, Cheng, X, Klimasauskas, S. 登録日 2000-08-08 公開日 2000-12-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Functional roles of the conserved threonine 250 in the target recognition domain of HhaI DNA methyltransferase. J.Biol.Chem., 275, 2000
2HMY	BINARY COMPLEX OF HHAI METHYLTRANSFERASE WITH ADOMET FORMED IN THE PRESENCE OF A SHORT NONPSECIFIC DNA OLIGONUCLEOTIDE 分子名称: PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI), S-ADENOSYLMETHIONINE 著者 O'Gara, M, Zhang, X, Roberts, R.J, Cheng, X. 登録日 1999-02-08 公開日 1999-03-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structure of a binary complex of HhaI methyltransferase with S-adenosyl-L-methionine formed in the presence of a short non-specific DNA oligonucleotide. J.Mol.Biol., 287, 1999
10MH	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND HEMIMETHYLATED DNA CONTAINING 5,6-DIHYDRO-5-AZACYTOSINE AT THE TARGET 分子名称: DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*5NCP*GP*CP*AP*TP*GP*G)-3'), PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI), ... 著者 Sheikhnejad, G, Brank, A, Christman, J.K, Goddard, A, Alvarez, E, Ford Junior, H, Marquez, V.E, Marasco, C.J, Sufrin, J.R, O'Gara, M, Cheng, X. 登録日 1998-08-10 公開日 1999-02-09 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine. J.Mol.Biol., 285, 1999
9MHT	CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX 分子名称: 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ... 著者 O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X. 登録日 1998-08-07 公開日 1998-12-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base. Nat.Struct.Biol., 5, 1998
7MHT	CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX 分子名称: 5'-D(P*CP*CP*AP*TP*GP*AP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ... 著者 O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X. 登録日 1998-08-05 公開日 1998-11-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base. Nat.Struct.Biol., 5, 1998
8MHT	CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX 分子名称: 5'-D(P*CP*CP*AP*TP*GP*UP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ... 著者 O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X. 登録日 1998-08-06 公開日 1998-11-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base. Nat.Struct.Biol., 5, 1998
6MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND DNA CONTAINING 4'-THIO-2'DEOXYCYTIDINE AT THE TARGET 分子名称: CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(4SC)P*GP*CP*AP*TP*GP*G)-3'), ... 著者 Cheng, X. 登録日 1998-08-05 公開日 1998-08-12 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase. Nucleic Acids Res., 25, 1997
5MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH HEMIMETHYLATED DNA AND ADOHCY 分子名称: DNA (5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3'), PROTEIN (HHAI METHYLTRANSFERASE), ... 著者 Cheng, X. 登録日 1996-10-22 公開日 1997-07-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A structural basis for the preferential binding of hemimethylated DNA by HhaI DNA methyltransferase. J.Mol.Biol., 263, 1996
3MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH UNMODIFIED DNA AND ADOHCY 分子名称: DNA (5'-D(*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ... 著者 O'Gara, M, Klimasauskas, S, Roberts, R.J, Cheng, X. 登録日 1996-07-24 公開日 1997-01-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes. J.Mol.Biol., 261, 1996
4MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH NATIVE DNA AND ADOHCY 分子名称: DNA (5'-D(*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ... 著者 Cheng, X. 登録日 1996-07-24 公開日 1997-01-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes. J.Mol.Biol., 261, 1996
1DCT	DNA (CYTOSINE-5) METHYLASE FROM HAEIII COVALENTLY BOUND TO DNA 分子名称: CALCIUM ION, DNA (5'-D(*AP*CP*CP*AP*GP*CP*AP*GP*GP*(C49)P*CP*AP*CP*CP*AP*GP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*CP*TP*GP*GP*TP*GP*GP*(C5M)P*CP*TP*GP*CP*TP*GP*G)-3'), ... 著者 Reinisch, K.M, Chen, L, Verdine, G.L, Lipscomb, W.N. 登録日 1995-05-17 公開日 1995-09-15 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing. Cell(Cambridge,Mass.), 82, 1995
1MHT	COVALENT TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE, DNA AND S-ADENOSYL-L-HOMOCYSTEINE 分子名称: DNA (5'-D(*TP*GP*AP*TP*AP*GP*(C36)P*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*AP*GP*(C36)P*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE), ... 著者 Cheng, X. 登録日 1994-12-08 公開日 1995-06-03 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 HhaI methyltransferase flips its target base out of the DNA helix. Cell(Cambridge,Mass.), 76, 1994
1HMY	CRYSTAL STRUCTURE OF THE HHAI DNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYL-L-METHIONINE 分子名称: HaeIII METHYLTRANSFERASE, S-ADENOSYLMETHIONINE 著者 Cheng, X. 登録日 1993-08-05 公開日 1993-10-31 最終更新日 2012-02-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine. Cell(Cambridge,Mass.), 74, 1993

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