PDB: 117 resultsInfo pagesStatus searchChemie searchBIRD

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3AV5	Crystal structure of mouse DNA methyltransferase 1 with AdoHcy Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION Authors: Takeshita, K, Suetake, I, Yamashita, E, Suga, M, Narita, H, Nakagawa, A, Tajima, S. Deposit date: 2011-02-22 Release date: 2011-05-04 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). Proc.Natl.Acad.Sci.USA, 108, 2011
3AV6	Crystal structure of mouse DNA methyltransferase 1 with AdoMet Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYLMETHIONINE, ZINC ION Authors: Takeshita, K, Suetake, I, Yamashita, E, Suga, M, Narita, H, Nakagawa, A, Tajima, S. Deposit date: 2011-02-22 Release date: 2011-05-04 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.09 Å) Cite: Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). Proc.Natl.Acad.Sci.USA, 108, 2011
3EEO	M. HhaI co-crystallized with synthetic dsDNA containing a propane diol in place of the deoxycytidine residue targeted for methylation. Descriptor: 5'-D(P*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3', 5'-D(P*DGP*DTP*DCP*DAP*DGP*(PDI)P*DGP*DCP*DAP*DTP*DGP*DG)-3', Modification methylase HhaI, ... Authors: Porta, J.C, Christman, J.K, Borgstahl, G.E.O. Deposit date: 2008-09-05 Release date: 2010-03-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.94 Å) Cite: M. HhaI co-crystallized with synthetic dsDNA containing a propane diol in place of the deoxycytidine residue targeted for methylation. To be Published
3G7U	Crystal structure of putative DNA modification methyltransferase encoded within prophage Cp-933R (E.coli) Descriptor: CHLORIDE ION, Cytosine-specific methyltransferase, GLYCEROL Authors: Patskovsky, Y, Ramagopal, U.A, Toro, R, Gilmore, M, Iizuka, M, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2009-02-10 Release date: 2009-02-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal Structure of DNA Modification Methyltransferase Encoded within Prophage Cp-933R (E.coli) To be Published
3MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH UNMODIFIED DNA AND ADOHCY Descriptor: DNA (5'-D(*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ... Authors: O'Gara, M, Klimasauskas, S, Roberts, R.J, Cheng, X. Deposit date: 1996-07-24 Release date: 1997-01-27 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes. J.Mol.Biol., 261, 1996
3PT6	Crystal structure of mouse DNMT1(650-1602) in complex with DNA Descriptor: DNA (5'-D(*CP*CP*TP*GP*CP*GP*GP*AP*GP*GP*CP*TP*CP*AP*CP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*CP*CP*GP*CP*AP*GP*G)-3'), DNA (cytosine-5)-methyltransferase 1, ... Authors: Song, J, Patel, D.J. Deposit date: 2010-12-02 Release date: 2010-12-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science, 331, 2011
3PT9	Crystal structure of mouse DNMT1(731-1602) in the free state Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION Authors: Song, J, Patel, D.J. Deposit date: 2010-12-02 Release date: 2010-12-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science, 331, 2011
3PTA	Crystal structure of human DNMT1(646-1600) in complex with DNA Descriptor: DNA (5'-D(*CP*CP*TP*GP*CP*GP*GP*AP*GP*GP*CP*TP*CP*AP*CP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*CP*CP*GP*CP*AP*GP*G)-3'), DNA (cytosine-5)-methyltransferase 1, ... Authors: Song, J, Patel, D.J. Deposit date: 2010-12-02 Release date: 2010-12-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science, 331, 2011
3QV2	Structure Analysis of Entamoeba histolytica methyltransferase EhMeth Descriptor: 5-cytosine DNA methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION Authors: Schulz, E.C, Roth, H.M, Ankri, S, Ficner, R. Deposit date: 2011-02-25 Release date: 2012-04-11 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structure Analysis of Entamoeba histolytica Methyltransferase To be Published
3SWR	Structure of human DNMT1 (601-1600) in complex with Sinefungin Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (cytosine-5)-methyltransferase 1, ... Authors: Hashimoto, H, Cheng, X. Deposit date: 2011-07-14 Release date: 2011-08-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Structure of human DNMT1 (residues 600-1600) in complex with Sinefungin To be Published
3UBT	Crystal Structure of C71S Mutant of DNA Cytosine-5 Methyltransferase M.HaeIII Bound to DNA Descriptor: 5'-D(*TP*GP*GP*CP*CP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... Authors: Verdine, G.L, Didovyk, A. Deposit date: 2011-10-24 Release date: 2012-10-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.502 Å) Cite: Structural origins of DNA target selection and nucleobase extrusion by a DNA Cytosine methyltransferase. J.Biol.Chem., 287, 2012
4DA4	Structure of mouse DNMT1 (731-1602) bound to hemimethylated CpG DNA Descriptor: CITRIC ACID, DNA (cytosine-5)-methyltransferase 1, DNA_LOWER_STRAND, ... Authors: Song, J, Patel, D.J. Deposit date: 2012-01-12 Release date: 2012-02-22 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation. Science, 335, 2012
4DKJ	CpG specific methyltransferase in complex with target DNA Descriptor: Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(C37)P*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3'), ... Authors: Wojciechowski, M, Czapinska, H, Bochtler, M. Deposit date: 2012-02-03 Release date: 2012-12-05 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI. Proc.Natl.Acad.Sci.USA, 110, 2013
4FSX	crystal structure of Se-substituted Zea mays ZMET2 in complex with SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4FT2	crystal structure of Zea mays ZMET2 in complex H3(1-15)K9me2 peptide and SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, H3 peptide, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4FT4	crystal structure of Zea mays ZMET2 in complex H3(1-32)K9me2 peptide and SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, H3(1-32)K9me2 peptide, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4H0N	Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant Descriptor: CALCIUM ION, DNMT2, S-ADENOSYL-L-HOMOCYSTEINE Authors: Li, S, Du, J, Yang, H, Yin, J, Zhong, J, Ding, J. Deposit date: 2012-09-09 Release date: 2012-11-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.712 Å) Cite: Functional and structural characterization of DNMT2 from Spodoptera frugiperda. J Mol Cell Biol, 5, 2013
4MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH NATIVE DNA AND ADOHCY Descriptor: DNA (5'-D(*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ... Authors: Cheng, X. Deposit date: 1996-07-24 Release date: 1997-01-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes. J.Mol.Biol., 261, 1996
4ONJ	Crystal structure of the catalytic domain of ntDRM Descriptor: DNA methyltransferase, SINEFUNGIN Authors: Du, J, Patel, D.J. Deposit date: 2014-01-28 Release date: 2014-06-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.807 Å) Cite: Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell(Cambridge,Mass.), 157, 2014
4ONQ	Crystal structure of ntDRM E283S/R309S/F310S/Y590S/D591S mutant Descriptor: DNA methyltransferase, SINEFUNGIN Authors: Du, J, Patel, D.J. Deposit date: 2014-01-28 Release date: 2014-06-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.502 Å) Cite: Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell(Cambridge,Mass.), 157, 2014
4U7P	Crystal structure of DNMT3A-DNMT3L complex Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... Authors: Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y. Deposit date: 2014-07-31 Release date: 2014-11-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.821 Å) Cite: Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4U7T	Crystal structure of DNMT3A-DNMT3L in complex with histone H3 Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... Authors: Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y. Deposit date: 2014-07-31 Release date: 2014-11-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4WXX	The crystal structure of human DNMT1(351-1600) Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION Authors: Zhang, Z.M, Song, J. Deposit date: 2014-11-14 Release date: 2015-07-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.622 Å) Cite: Crystal Structure of Human DNA Methyltransferase 1. J.Mol.Biol., 427, 2015
4YOC	Crystal Structure of human DNMT1 and USP7/HAUSP complex Descriptor: DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION Authors: Cheng, J, Yang, H, Fang, J, Gong, R, Wang, P, Li, Z, Xu, Y. Deposit date: 2015-03-11 Release date: 2015-05-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.916 Å) Cite: Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation. Nat Commun, 6, 2015
5CIY	Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain Descriptor: DNA (5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3'), Modification methylase HhaI, ... Authors: Rondelet, G, DAL MASO, T, Willems, L, Wouters, J. Deposit date: 2015-07-13 Release date: 2016-03-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.594 Å) Cite: Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B. J.Struct.Biol., 194, 2016

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