PDB: 143 resultsInfo pagesStatus searchChemie searchBIRD

---

7RMO	Yeast CTP Synthase (Ura7) Bundle bound to Products at low pH Descriptor: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-27 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (7 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RKH	Yeast CTP Synthase (URA8) tetramer bound to ATP/UTP at neutral pH Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, MAGNESIUM ION, ... Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-22 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RMV	Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, URIDINE 5'-TRIPHOSPHATE Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-28 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (6.7 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RL0	Yeast CTP Synthase (URA8) Filament bound to ATP/UTP at low pH Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, MAGNESIUM ION, ... Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-22 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RMC	Yeast CTP Synthase (Ura7) filament bound to CTP at low pH Descriptor: CTP synthase 1, CYTIDINE-5'-TRIPHOSPHATE Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-27 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RNL	Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates Descriptor: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION Authors: Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. Deposit date: 2021-07-29 Release date: 2021-11-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7SBC	Crystal structure of a GMP synthase from Acinetobacter baumannii AB5075-UW Descriptor: CHLORIDE ION, GMP synthase [glutamine-hydrolyzing], MAGNESIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-09-24 Release date: 2021-10-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of a GMP synthase from Acinetobacter baumannii AB5075-UW To Be Published
7MIH	Human CTPS2 bound to inhibitor R80 Descriptor: CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... Authors: Lynch, E.M, Dimattia, M.A, Kollman, J.M. Deposit date: 2021-04-16 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIG	Human CTPS1 bound to inhibitor T35 Descriptor: 2-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}-2-methyl-N-{5-[6-(trifluoromethyl)pyrazin-2-yl]pyridin-2-yl}propanamide, CTP synthase 1, GLUTAMINE, ... Authors: Lynch, E.M, Dimattia, M.A, Kollman, J.M. Deposit date: 2021-04-16 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MH0	Human CTPS1 bound to CTP Descriptor: CTP synthase 1, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION Authors: Lynch, E.M, Kollman, J.M. Deposit date: 2021-04-14 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIV	Mouse CTPS2-I250T bound to inhibitor R80 Descriptor: CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... Authors: Lynch, E.M, Dimattia, M.A, Kollman, J.M. Deposit date: 2021-04-17 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MII	Human CTPS2 bound to inhibitor T35 Descriptor: 2-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}-2-methyl-N-{5-[6-(trifluoromethyl)pyrazin-2-yl]pyridin-2-yl}propanamide, CTP synthase 2, GLUTAMINE, ... Authors: Lynch, E.M, Dimattia, M.A, Kollman, J.M. Deposit date: 2021-04-16 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MH1	Human CTPS2 bound to CTP Descriptor: CTP synthase 2, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION Authors: Lynch, E.M, Kollman, J.M. Deposit date: 2021-04-14 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIF	Human CTPS1 bound to inhibitor R80 Descriptor: CTP synthase 1, GLUTAMINE, MAGNESIUM ION, ... Authors: Lynch, E.M, Dimattia, M.A, Kollman, J.M. Deposit date: 2021-04-16 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MGZ	Human CTPS1 bound to UTP, AMPPNP, and glutamine Descriptor: CTP synthase 1, GLUTAMINE, MAGNESIUM ION, ... Authors: Lynch, E.M, Dimattia, M.A, Kollman, J.M. Deposit date: 2021-04-14 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIU	Mouse CTPS2 bound to inhibitor R80 Descriptor: CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... Authors: Lynch, E.M, Dimattia, M.A, Kollman, J.M. Deposit date: 2021-04-17 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIP	Mouse CTPS1 bound to inhibitor R80 Descriptor: CTP synthase 1, GLUTAMINE, MAGNESIUM ION, ... Authors: Lynch, E.M, Dimattia, M.A, Kollman, J.M. Deposit date: 2021-04-17 Release date: 2021-10-13 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MO6	Guanosine Monophosphate Synthase from Aspergillus fumigatus Af293 Descriptor: GMP synthase [glutamine-hydrolyzing] Authors: Nguyen, S, Bruning, J.B. Deposit date: 2021-05-01 Release date: 2022-02-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural insights into the antifungal drug target guanosine monophosphate synthase from Aspergillus fumigatus. Acta Crystallogr D Struct Biol, 78, 2022

<123456