PDB: 143 件ウェブページステータス検索Chemie searchBIRD

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7RMO	Yeast CTP Synthase (Ura7) Bundle bound to Products at low pH 分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE 著者 Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. 登録日 2021-07-27 公開日 2021-11-24 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RL0	Yeast CTP Synthase (URA8) Filament bound to ATP/UTP at low pH 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, MAGNESIUM ION, ... 著者 Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. 登録日 2021-07-22 公開日 2021-11-24 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RMV	Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, URIDINE 5'-TRIPHOSPHATE 著者 Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. 登録日 2021-07-28 公開日 2021-11-24 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RMK	Yeast CTP Synthase (Ura7) Bundle bound to substrates at low pH 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, URIDINE 5'-TRIPHOSPHATE 著者 Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. 登録日 2021-07-27 公開日 2021-11-24 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RNR	Yeast CTP Synthase (Ura8) Bundle Bound to Substrates at Low pH 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, MAGNESIUM ION, ... 著者 Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. 登録日 2021-07-29 公開日 2021-11-24 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7RNL	Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates 分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. 登録日 2021-07-29 公開日 2021-11-24 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
7MIF	Human CTPS1 bound to inhibitor R80 分子名称: CTP synthase 1, GLUTAMINE, MAGNESIUM ION, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-16 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIP	Mouse CTPS1 bound to inhibitor R80 分子名称: CTP synthase 1, GLUTAMINE, MAGNESIUM ION, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-17 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MGZ	Human CTPS1 bound to UTP, AMPPNP, and glutamine 分子名称: CTP synthase 1, GLUTAMINE, MAGNESIUM ION, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-14 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIV	Mouse CTPS2-I250T bound to inhibitor R80 分子名称: CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-17 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MII	Human CTPS2 bound to inhibitor T35 分子名称: 2-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}-2-methyl-N-{5-[6-(trifluoromethyl)pyrazin-2-yl]pyridin-2-yl}propanamide, CTP synthase 2, GLUTAMINE, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-16 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIG	Human CTPS1 bound to inhibitor T35 分子名称: 2-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}-2-methyl-N-{5-[6-(trifluoromethyl)pyrazin-2-yl]pyridin-2-yl}propanamide, CTP synthase 1, GLUTAMINE, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-16 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MH1	Human CTPS2 bound to CTP 分子名称: CTP synthase 2, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Lynch, E.M, Kollman, J.M. 登録日 2021-04-14 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MH0	Human CTPS1 bound to CTP 分子名称: CTP synthase 1, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Lynch, E.M, Kollman, J.M. 登録日 2021-04-14 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIU	Mouse CTPS2 bound to inhibitor R80 分子名称: CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-17 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIH	Human CTPS2 bound to inhibitor R80 分子名称: CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-16 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7SBC	Crystal structure of a GMP synthase from Acinetobacter baumannii AB5075-UW 分子名称: CHLORIDE ION, GMP synthase [glutamine-hydrolyzing], MAGNESIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-09-24 公開日 2021-10-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of a GMP synthase from Acinetobacter baumannii AB5075-UW To Be Published
7MO6	Guanosine Monophosphate Synthase from Aspergillus fumigatus Af293 分子名称: GMP synthase [glutamine-hydrolyzing] 著者 Nguyen, S, Bruning, J.B. 登録日 2021-05-01 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insights into the antifungal drug target guanosine monophosphate synthase from Aspergillus fumigatus. Acta Crystallogr D Struct Biol, 78, 2022

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