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8RM6
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BU of 8rm6 by Molmil
Crystal Structure of Human Androgen Receptor DNA Binding Domain Bound to its Response Element: C3(1)ARE
分子名称: C3(1)ARE_Chain C, C3(1)ARE_Chain D, Isoform 2 of Androgen receptor, ...
著者Lee, X.Y, Helsen, C, Van Eynde, W, Voet, A, Claessens, F.
登録日2024-01-05
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural mechanism underlying variations in DNA binding by the androgen receptor.
J.Steroid Biochem.Mol.Biol., 241, 2024
5VA0
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BU of 5va0 by Molmil
Glucocorticoid Receptor DNA Binding Domain in complex with AP-1 response element from VCAM-1 Promoter
分子名称: DNA (5'-D(*CP*GP*GP*CP*TP*GP*AP*CP*TP*CP*AP*TP*CP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*GP*AP*TP*GP*AP*GP*TP*CP*AP*GP*CP*CP*G)-3'), Glucocorticoid receptor, ...
著者Weikum, E.R, Ortlund, E.A.
登録日2017-03-24
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.295 Å)
主引用文献Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes.
Nucleic Acids Res., 45, 2017
5VA7
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BU of 5va7 by Molmil
Glucocorticoid Receptor DNA Binding Domain - IL11 AP-1 recognition element Complex
分子名称: DNA (5'-D(*AP*GP*GP*GP*TP*GP*AP*GP*TP*CP*AP*GP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*CP*TP*GP*AP*CP*TP*CP*AP*CP*CP*CP*T)-3'), Glucocorticoid receptor, ...
著者Weikum, E.R, Ortlund, E.A.
登録日2017-03-24
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes.
Nucleic Acids Res., 45, 2017
1CIT
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BU of 1cit by Molmil
DNA-BINDING MECHANISM OF THE MONOMERIC ORPHAN NUCLEAR RECEPTOR NGFI-B
分子名称: DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3'), PROTEIN (ORPHAN NUCLEAR RECEPTOR NGFI-B), ...
著者Meinke, G, Sigler, P.B.
登録日1999-04-05
公開日1999-05-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献DNA-binding mechanism of the monomeric orphan nuclear receptor NGFI-B.
Nat.Struct.Biol., 6, 1999
6BQU
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BU of 6bqu by Molmil
Human GR (418-507) in complex with monomeric DNA binding site
分子名称: DNA (5'-D(P*AP*AP*GP*CP*TP*AP*GP*TP*AP*CP*AP*TP*TP*TP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*AP*AP*TP*GP*TP*AP*CP*TP*AP*GP*CP*T)-3'), Glucocorticoid receptor, ...
著者Pufall, M.A.
登録日2017-11-28
公開日2018-12-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献General and sequence-specific roles for DNA in glucocorticoid receptor DNA-binding stoichiometry
To Be Published
6BSF
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BU of 6bsf by Molmil
Human GR (418-507) in complex with monomeric DNA binding site
分子名称: DNA (5'-D(P*AP*AP*GP*CP*TP*AP*GP*TP*AP*CP*AP*TP*TP*TP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*AP*AP*TP*GP*TP*AP*CP*TP*AP*GP*CP*T)-3'), Glucocorticoid receptor, ...
著者Pufall, M.A.
登録日2017-12-02
公開日2018-12-05
最終更新日2021-08-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献General and sequence-specific roles for DNA in glucocorticoid receptor DNA-binding stoichiometry
To Be Published
6BSE
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BU of 6bse by Molmil
Glucocorticoid receptor bound to high cooperativity monomer sequence
分子名称: DNA (5'-D(P*AP*CP*CP*AP*CP*GP*TP*GP*TP*AP*CP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*AP*GP*TP*AP*CP*AP*CP*GP*TP*GP*G)-3'), Glucocorticoid receptor, ...
著者Pufall, M.A.
登録日2017-12-02
公開日2018-12-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献General and sequence-specific roles for DNA in glucocorticoid receptor DNA-binding stoichiometry
To Be Published
6CFN
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BU of 6cfn by Molmil
Crystal Structure of the DNA-free Glucocorticoid Receptor DNA Binding Domain
分子名称: Glucocorticoid receptor, ZINC ION
著者Frank, F, Okafor, C.D, Ortlund, E.A.
登録日2018-02-15
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The first crystal structure of a DNA-free nuclear receptor DNA binding domain sheds light on DNA-driven allostery in the glucocorticoid receptor.
Sci Rep, 8, 2018
4CN3
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BU of 4cn3 by Molmil
Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Gde1SpA Response Element
分子名称: 5'-D(*CP*TP*AP*GP*TP*TP*CP*AP*AP*AP*GP*TP*TP*CP *AP*CP*A)-3', 5'-D(*TP*GP*TP*GP*AP*AP*CP*TP*TP*TP*GP*AP*AP*CP *TP*AP*G)-3', RETINOIC ACID RECEPTOR RXR-ALPHA, ...
著者McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N.
登録日2014-01-21
公開日2015-02-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor.
Sci.Rep., 5, 2015
4CN5
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BU of 4cn5 by Molmil
Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Nr1d1 Response Element
分子名称: 5'-D(*AP*TP*TP*GP*AP*AP*CP*TP*CP*TP*GP*AP*CP*CP *CP*CP*AP)-3', 5'-D(*TP*GP*GP*GP*GP*TP*CP*AP*GP*AP*GP*TP*TP*CP *AP*AP*TP)-3', CHLORIDE ION, ...
著者McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N.
登録日2014-01-21
公開日2015-02-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor.
Sci.Rep., 5, 2015
4CN2
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BU of 4cn2 by Molmil
Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Ramp2 Response Element
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*AP*TP*TP*GP*AP*CP*CP*CP*TP*TP*GP*AP*AP*DC *TP*CP*AP)-3', 5'-D(*TP*GP*AP*GP*TP*TP*CP*AP*AP*GP*GP*GP*TP*DC *AP*AP*TP)-3', ...
著者McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N.
登録日2014-01-21
公開日2015-02-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.069 Å)
主引用文献Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor.
Sci.Rep., 5, 2015
6XWG
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BU of 6xwg by Molmil
Crystal Structure of the Human RXR/RAR DNA-Binding Domain Heterodimer Bound to the Human RARb2 DR5 Response Element
分子名称: CHLORIDE ION, GLYCEROL, RARb2 DR5 Response Element, ...
著者McEwen, A.G, Poussin-Courmontagne, P, Peluso-Iltis, C, Rochel, N.
登録日2020-01-23
公開日2020-09-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
Nucleic Acids Res., 48, 2020
4CN7
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BU of 4cn7 by Molmil
Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to an idealized DR1 Response Element
分子名称: 5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP *AP*GP)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP *AP*GP)-3', CHLORIDE ION, ...
著者McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N.
登録日2014-01-21
公開日2015-02-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor.
Sci.Rep., 5, 2015
6XWH
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BU of 6xwh by Molmil
Crystal Structure of the Human RXR DNA-Binding Domain Homodimer Bound to the Human Hoxb13 DR0 Response Element
分子名称: Hoxb13 DR0 Response Element, 3'-5' strand, 5'-3' strand, ...
著者McEwen, A.G, Poussin-Courmontagne, P, Peluso-Iltis, C, Rochel, N.
登録日2020-01-23
公開日2020-09-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
Nucleic Acids Res., 48, 2020
6X6E
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BU of 6x6e by Molmil
Glucocorticoid Receptor DNA binding domain in complex with methylated precursor for a modern recognition element (methylated pre-GBS)
分子名称: DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*GP*GP*AP*GP*(5CM)P*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*GP*CP*TP*CP*(5CM)P*GP*TP*TP*CP*TP*G)-3'), Glucocorticoid receptor, ...
著者Liu, X, Ortlund, E.A.
登録日2020-05-28
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element.
Nucleic Acids Res., 49, 2021
6X6D
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BU of 6x6d by Molmil
Glucocorticoid Receptor DNA binding domain in complex with unmodified precursor for a modern recognition element (pre-GBS)
分子名称: CACODYLATE ION, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*GP*GP*AP*GP*CP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*GP*CP*TP*CP*CP*GP*TP*TP*CP*TP*G)-3'), ...
著者Liu, X, Ortlund, E.A.
登録日2020-05-28
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element.
Nucleic Acids Res., 49, 2021
6FBQ
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BU of 6fbq by Molmil
Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human MEp DR1 Response Element, pH 7.0
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, DNA (5'-D(*CP*TP*GP*GP*GP*TP*CP*AP*AP*AP*GP*TP*TP*CP*AP*TP*C)-3'), DNA (5'-D(*GP*AP*TP*GP*AP*AP*CP*TP*TP*TP*GP*AP*CP*CP*CP*AP*G)-3'), ...
著者McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N.
登録日2017-12-19
公開日2018-12-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Modulation of RXR-DNA complex assembly by DNA context.
Mol. Cell. Endocrinol., 481, 2019
6FBR
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BU of 6fbr by Molmil
Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human MEp DR1 Response Element, pH 4.2
分子名称: DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*TP*GP*GP*GP*TP*CP*AP*AP*AP*GP*TP*TP*CP*AP*TP*C)-3'), DNA (5'-D(*GP*AP*TP*GP*AP*AP*CP*TP*TP*TP*GP*AP*CP*CP*CP*AP*G)-3'), ...
著者McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N.
登録日2017-12-19
公開日2018-12-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Modulation of RXR-DNA complex assembly by DNA context.
Mol. Cell. Endocrinol., 481, 2019
1KB4
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BU of 1kb4 by Molmil
Crystal Structure of VDR DNA-binding Domain Bound to a Canonical Direct Repeat with Three Base Pair Spacer (DR3) Response Element
分子名称: 5'-D(*CP*AP*CP*AP*GP*GP*TP*CP*AP*CP*GP*AP*AP*GP*GP*TP*CP*A)-3', 5'-D(*TP*GP*AP*CP*CP*TP*TP*CP*GP*TP*GP*AP*CP*CP*TP*GP*TP*G)-3', Vitamin D3 Receptor, ...
著者Shaffer, P.L, Gewirth, D.T.
登録日2001-11-05
公開日2002-05-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of VDR-DNA interactions on direct repeat response elements.
EMBO J., 21, 2002
1KB6
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BU of 1kb6 by Molmil
Crystal Structure of VDR DNA-binding Domain Bound to Rat Osteocalcin (OC) Response Element
分子名称: 5'-D(*CP*AP*CP*GP*GP*GP*TP*GP*AP*AP*TP*GP*AP*GP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*CP*TP*CP*AP*TP*TP*CP*AP*CP*CP*CP*GP*TP*G)-3', Vitamin D3 Receptor, ...
著者Shaffer, P.L, Gewirth, D.T.
登録日2001-11-05
公開日2002-05-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of VDR-DNA interactions on direct repeat response elements.
EMBO J., 21, 2002
1KB2
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BU of 1kb2 by Molmil
Crystal Structure of VDR DNA-binding Domain Bound to Mouse Osteopontin (SPP) Response Element
分子名称: 5'-D(*CP*AP*CP*GP*GP*TP*TP*CP*AP*CP*GP*AP*GP*GP*TP*TP*CP*A)-3', 5'-D(*TP*GP*AP*AP*CP*CP*TP*CP*GP*TP*GP*AP*AP*CP*CP*GP*TP*G)-3', Vitamin D3 Receptor, ...
著者Shaffer, P.L, Gewirth, D.T.
登録日2001-11-05
公開日2002-05-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of VDR-DNA interactions on direct repeat response elements.
EMBO J., 21, 2002
1LAT
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BU of 1lat by Molmil
GLUCOCORTICOID RECEPTOR MUTANT/DNA COMPLEX
分子名称: DNA (5'-D(*TP*TP*CP*CP*AP*GP*AP*AP*CP*AP*TP*GP*TP*TP*CP*TP*G P*GP*A)-3'), GLUCOCORTICOID RECEPTOR, ZINC ION
著者Gewirth, D.T, Sigler, P.B.
登録日1995-12-18
公開日1996-04-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The basis for half-site specificity explored through a non-cognate steroid receptor-DNA complex.
Nat.Struct.Biol., 2, 1995
1LO1
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BU of 1lo1 by Molmil
ESTROGEN RELATED RECEPTOR 2 DNA BINDING DOMAIN IN COMPLEX WITH DNA
分子名称: 5'-D(*CP*GP*TP*GP*AP*CP*CP*TP*TP*GP*AP*GP*C)-3', 5'-D(*GP*CP*TP*CP*AP*AP*GP*GP*TP*CP*AP*CP*G)-3', Steroid hormone receptor ERR2, ...
著者Gearhart, M.D, Holmbeck, S.M.A, Evans, R.M, Dyson, H.J, Wright, P.E.
登録日2002-05-05
公開日2003-04-22
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Monomeric Complex of Human Orphan Estrogen Related Receptor-2 with DNA: A Pseudo-dimer Interface Mediates Extended Half-site Recognition
J.Mol.Biol., 327, 2003
7XV6
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BU of 7xv6 by Molmil
Crystal structure of the Human TR4 DNA-Binding Domain with C-terminal extension (DBD-CTE) Homodimer Bound to DR1 Response Element
分子名称: DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*AP*GP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3'), NR2C2 protein, ...
著者Liu, Y, Chen, Z.
登録日2022-05-21
公開日2022-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.
Nucleic Acids Res., 51, 2023
7XV9
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BU of 7xv9 by Molmil
Crystal structure of the Human TR4 DNA-Binding Domain
分子名称: Nuclear receptor subfamily 2 group C member 2, ZINC ION
著者Liu, Y, Chen, Z.
登録日2022-05-21
公開日2022-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.
Nucleic Acids Res., 51, 2023

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