PDB: 657 件ウェブページステータス検索Chemie searchBIRD

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6MMK	Diheteromeric NMDA receptor GluN1/GluN2A in the '1-Knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. 登録日 2018-09-30 公開日 2018-11-28 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (6.08 Å) 主引用文献 Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
6MMA	Diheteromeric NMDA receptor GluN1/GluN2A in the 'Extended' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 6.1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ... 著者 Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. 登録日 2018-09-29 公開日 2018-11-28 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (6.31 Å) 主引用文献 Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
6MMT	Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '1-Knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. 登録日 2018-10-01 公開日 2018-11-28 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (7.46 Å) 主引用文献 Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
3RT6	Fluorowillardiine bound to the ligand binding domain of GluA3 分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 3, ZINC ION 著者 Ahmed, A.H, Oswald, R.E. 登録日 2011-05-03 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.836 Å) 主引用文献 Mechanisms of Modal Activation of GluA3 Receptors. Mol.Pharmacol., 80, 2011
3RT8	Chlorowillardiine bound to the ligand binding domain of GluA3 分子名称: 3-(5-chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine, Glutamate receptor 3, ZINC ION 著者 Ahmed, A.H, Oswald, R.E. 登録日 2011-05-03 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.426 Å) 主引用文献 Mechanisms of Modal Activation of GluA3 Receptors. Mol.Pharmacol., 80, 2011
6MMP	Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 0.1 millimolar EDTA, and at pH 8.0 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. 登録日 2018-10-01 公開日 2018-11-28 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (6.88 Å) 主引用文献 Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
6MML	Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. 登録日 2018-09-30 公開日 2018-11-28 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (7.14 Å) 主引用文献 Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
6MMI	Diheteromeric NMDA receptor GluN1/GluN2A in the 'Splayed-Open' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar zinc chloride, and at pH 7.4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. 登録日 2018-09-30 公開日 2018-11-28 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (8.93 Å) 主引用文献 Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
6MMM	Diheteromeric NMDA receptor GluN1/GluN2A in the 'Extended-1' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. 登録日 2018-09-30 公開日 2018-11-28 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (6.84 Å) 主引用文献 Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
3RTW	Nitrowillardiine bound to the ligand binding domain of GluA2 分子名称: 3-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine, Glutamate receptor 2, ZINC ION 著者 Ahmed, A.H, Oswald, R.E. 登録日 2011-05-04 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.095 Å) 主引用文献 Mechanisms of Modal Activation of GluA3 Receptors. Mol.Pharmacol., 80, 2011
6MM9	Diheteromeric NMDA receptor GluN1/GluN2A in the '1-Knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 6.1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ... 著者 Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. 登録日 2018-09-29 公開日 2018-11-28 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (5.97 Å) 主引用文献 Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
6MMU	Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. 登録日 2018-10-01 公開日 2018-11-28 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (5.3 Å) 主引用文献 Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
3S2V	Crystal Structure of the Ligand Binding Domain of GluK1 in Complex with an Antagonist (S)-1-(2'-Amino-2'-carboxyethyl)-3-[(2-carboxythien-3-yl)methyl]thieno[3,4-d]pyrimidin-2,4-dione at 2.5 A Resolution 分子名称: (S)-1-(2'-AMINO-2'-CARBOXYETHYL)-3-[(2-CARBOXYTHIEN-3-YL)METHYL]THIENO[3,4-D]PYRIMIDIN-2,4-DIONE, CHLORIDE ION, GLYCEROL, ... 著者 Venskutonyte, R, Frydenvang, K, Kastrup, J.S. 登録日 2011-05-17 公開日 2011-06-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization. J.Med.Chem., 54, 2011
6NJM	Architecture and subunit arrangement of native AMPA receptors 分子名称: 15F1 Fab heavy chain, 15F1 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gouaux, E, Zhao, Y. 登録日 2019-01-03 公開日 2019-04-24 最終更新日 2021-05-05 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM. Science, 364, 2019
3S9E	Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with (S)-glutamate 分子名称: CHLORIDE ION, GLUTAMIC ACID, GLYCEROL, ... 著者 Venskutonyte, R, Frydenvang, K, Gajhede, M, Kastrup, J.S. 登録日 2011-06-01 公開日 2011-09-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate. J.Struct.Biol., 176, 2011
6NJL	Architecture and subunit arrangement of native AMPA receptors 分子名称: 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ... 著者 Gouaux, E, Zhao, Y. 登録日 2019-01-03 公開日 2019-04-24 最終更新日 2021-05-05 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM. Science, 364, 2019
6NJN	Architecture and subunit arrangement of native AMPA receptors 分子名称: 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ... 著者 Gouaux, E, Zhao, Y. 登録日 2019-01-03 公開日 2019-04-24 最終更新日 2021-05-05 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM. Science, 364, 2019
3T9V	CNQX bound to a reduced double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2 分子名称: 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile, Glutamate receptor 2, ZINC ION 著者 Ahmed, A.H, Oswald, R.E. 登録日 2011-08-03 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.975 Å) 主引用文献 Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS. J.Biol.Chem., 286, 2011
3T9X	Glutamate bound to a double cysteine mutant (V484C/E657C) of the ligand binding domain of GluA2 分子名称: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION 著者 Ahmed, A.H, Oswald, R.E. 登録日 2011-08-03 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.823 Å) 主引用文献 Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS. J.Biol.Chem., 286, 2011
3T96	Iodowillardiine bound to a double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2 分子名称: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2, ZINC ION 著者 Ahmed, A.H, Wang, S, Chuang, H.H, Oswald, R.E. 登録日 2011-08-02 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.872 Å) 主引用文献 Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS. J.Biol.Chem., 286, 2011
3T9H	Kainate bound to a double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2, ZINC ION 著者 Ahmed, A.H, Wang, S, Chuang, H.H, Oswald, R.E. 登録日 2011-08-02 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.015 Å) 主引用文献 Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS. J.Biol.Chem., 286, 2011
6O9G	Open state GluA2 in complex with STZ and blocked by AgTx-636, after micelle signal subtraction 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ... 著者 Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. 登録日 2019-03-13 公開日 2019-03-20 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors. Neuron, 99, 2018
3T93	Glutamate bound to a double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2 分子名称: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION 著者 Ahmed, A.H, Oswald, R.E. 登録日 2011-08-02 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.907 Å) 主引用文献 Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS. J.Biol.Chem., 286, 2011
3TDJ	Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and BPAM-97 at 1.95 A resolution 分子名称: 4-ethyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, CHLORIDE ION, GLUTAMIC ACID, ... 著者 Krintel, C, Frydenvang, K, Gajhede, M, Kastrup, J.S. 登録日 2011-08-11 公開日 2011-09-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. Biochem.J., 441, 2012
3T9U	CNQX bound to an oxidized double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2 分子名称: 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile, Glutamate receptor 2, ZINC ION 著者 Ahmed, A.H, Oswald, R.E. 登録日 2011-08-03 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS. J.Biol.Chem., 286, 2011

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