7ZXN
| cryo-EM structure of Connexin 32 gap junction channel | Descriptor: | CHOLESTEROL, Gap junction beta-1 protein | Authors: | Qi, C, Korkhov, V.M. | Deposit date: | 2022-05-21 | Release date: | 2023-05-31 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels. Sci Adv, 9, 2023
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7ZXO
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7ZXQ
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7ZXP
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7ZXM
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7ZXT
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7QEQ
| human Connexin 26 dodecamer at 90mmHg PCO2, pH7.4 | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-03-30 | Last modified: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (1.9 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7QER
| human Connexin 26 dodecamer at 55mm Hg PCO2, pH7.4 | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-03-30 | Last modified: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7QEW
| human Connexin 26 class 2 hexamer at 90mmHg PCO2, pH7.4 | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-03-30 | Last modified: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7QET
| human Connexin 26 dodecamer at 20mmHg PCO2, pH7.4 | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-03-30 | Last modified: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7QEY
| human Connexin 26 class 1 hexamer at 90mmHg PCO2, pH7.4 | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-03-30 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7QEU
| human Connexin 26 at 55mmHg PCO2, pH7.4: two masked subunits, class B | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7QEO
| human Connexin 26 at 55mm Hg PCO2, pH7.4: two masked subunits, class C | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7QEV
| human Connexin 26 at 55mm Hg PCO2, pH7.4:two masked subunits, class D | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7QES
| human Connexin 26 at 55mm Hg PCO2, pH7.4: two masked subunits, class A | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7F94
| Structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel with two conformationally different hemichannels | Descriptor: | A C-terminal deletion mutant of gap junction alpha-1 protein (Cx43-M257) | Authors: | Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. | Deposit date: | 2021-07-03 | Release date: | 2022-07-06 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14, 2023
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7JMD
| Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 1 | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | Deposit date: | 2020-07-31 | Release date: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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7JN0
| Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 2 | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.A, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | Deposit date: | 2020-08-03 | Release date: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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7JKC
| Sheep Connexin-46 at 1.9 angstroms resolution by CryoEM | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | Deposit date: | 2020-07-28 | Release date: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (1.9 Å) | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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7JN1
| Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 3 | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | Deposit date: | 2020-08-03 | Release date: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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7XNH
| Human Cx36/GJD2 gap junction channel with pore-lining N-terminal helices in soybean lipids | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-04-28 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XNV
| Structurally hetero-junctional human Cx36/GJD2 gap junction channel in soybean lipids (C6 symmetry) | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-04-29 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XL8
| Human Cx36/GJD2 (N-terminal deletion mutant) gap junction channel in soybean lipids (D6 symmetry) | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-04-21 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XKK
| Human Cx36/GJD2 gap junction channel in detergents | Descriptor: | Gap junction delta-2 protein | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-04-19 | Release date: | 2023-04-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XQG
| Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (GCN conformation) | Descriptor: | CHOLESTEROL HEMISUCCINATE, Gap junction alpha-1 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. | Deposit date: | 2022-05-07 | Release date: | 2023-01-25 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14, 2023
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