4BHP
 
 | |
4BH9
 | |
4N9H
 | | Crystal structure of Transcription regulation Protein CRP | | 分子名称: | Catabolite gene activator | | 著者 | Lee, B.J, Seok, S.H, Im, H, Yoon, H.J. | | 登録日 | 2013-10-21 | | 公開日 | 2014-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of inactive CRP species reveal the atomic details of the allosteric transition that discriminates cyclic nucleotide second messengers.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
4MX3
 | | Crystal Structure of PKA RIalpha Homodimer | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit | | 著者 | Bruystens, J.G.H, Wu, J, Fortezzo, A, Kornev, A.P, Blumenthal, D.A, Taylor, S.S. | | 登録日 | 2013-09-25 | | 公開日 | 2014-01-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.88 Å) | | 主引用文献 | PKA RI alpha Homodimer Structure Reveals an Intermolecular Interface with Implications for Cooperative cAMP Binding and Carney Complex Disease.
Structure, 22, 2014
|
|
4N9I
 | | Crystal Structure of Transcription regulation protein CRP complexed with cGMP | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, Catabolite gene activator | | 著者 | Lee, B.-J, Seok, S.-H, Im, H, Yoon, H.-J. | | 登録日 | 2013-10-21 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structures of inactive CRP species reveal the atomic details of the allosteric transition that discriminates cyclic nucleotide second messengers.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
6GYN
 | | Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | | 著者 | Shintre, C.A, Pike, A.C.W, Tessitore, A, Young, M, Bushell, S.R, Strain-Damerell, C, Mukhopadhyay, S, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2018-06-30 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
To Be Published
|
|
6GYO
 | | Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | | 著者 | Shintre, C.A, Pike, A.C.W, Tessitore, A, Young, M, Bushell, S.R, Strain-Damerell, C, Mukhopadhyay, S, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2018-06-30 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
To Be Published
|
|
4BYY
 | | Apo GlxR | | 分子名称: | GLYCEROL, PHOSPHATE ION, TRANSCRIPTIONAL REGULATOR, ... | | 著者 | Pohl, E, Cann, M.J, Townsend, P.D, Money, V.A. | | 登録日 | 2013-07-21 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors.
Plos One, 9, 2014
|
|
4CHW
 | | The electron crystallography structure of the cAMP-free potassium channel MloK1 | | 分子名称: | CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION | | 著者 | Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H. | | 登録日 | 2013-12-04 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7 Å) | | 主引用文献 | Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
Nat Commun, 5, 2014
|
|
6H7E
 | | GEF regulatory domain | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cDNA FLJ56134, ... | | 著者 | Ferrandez, Y, Cherfils, J, Peurois, F. | | 登録日 | 2018-07-31 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Membranes prime the RapGEF EPAC1 to transduce cAMP signaling.
Nat Commun, 14, 2023
|
|
4CHV
 | | The electron crystallography structure of the cAMP-bound potassium channel MloK1 | | 分子名称: | CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION | | 著者 | Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H. | | 登録日 | 2013-12-04 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7 Å) | | 主引用文献 | Ligand-Induced Structural Changes in the Cyclic Nucleotide-Modulated Potassium Channel Mlok1
Nat.Commun., 5, 2014
|
|
6HQ7
 | |
4CYD
 | | GlxR bound to cAMP | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, PROBABLE EXPRESSION TAG, ... | | 著者 | Townsend, P.D, Bott, M, Cann, M.J, Pohl, E. | | 登録日 | 2014-04-10 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors.
Plos One, 9, 2014
|
|
6HQ4
 | |
4DIN
 | | Novel Localization and Quaternary Structure of the PKA RI beta Holoenzyme | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... | | 著者 | Ilouz, R, Bubis, J, Wu, J, Yim, Y.Y, Deal, M.S, Kornev, A.P, Ma, Y, Blumenthal, D.K, Taylor, S.S. | | 登録日 | 2012-01-31 | | 公開日 | 2012-07-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Localization and quaternary structure of the PKA RI Beta holoenzyme
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
6HQ5
 | | Structure of EAL Enzyme Bd1971 - cAMP and cyclic-di-GMP bound form | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CALCIUM ION, ... | | 著者 | Lovering, A.L, Cadby, I.T. | | 登録日 | 2018-09-24 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Nucleotide signaling pathway convergence in a cAMP-sensing bacterial c-di-GMP phosphodiesterase.
Embo J., 38, 2019
|
|
4ONU
 | |
4ORF
 | |
4OLL
 | |
6I9D
 | | MloK1 consensus structure from single particle analysis of 2D crystals | | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | | 登録日 | 2018-11-23 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
|
|
6IAX
 | | MloK1 model from single particle analysis of 2D crystals, class 1 (extended conformation) | | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | | 登録日 | 2018-11-27 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
|
|
4EV0
 | | Crystal Structure of Thermus thermophilus Catabolite Activator Protein | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Hudson, B.P, Turo, K, Birktoft, J.J, Lawson, C.L. | | 登録日 | 2012-04-25 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | | 主引用文献 | Crystal Structure of T. thermophilius Catabolite Activator Protein
To be Published
|
|
4F7Z
 | | Conformational dynamics of exchange protein directly activated by cAMP | | 分子名称: | GLYCEROL, Rap guanine nucleotide exchange factor 4 | | 著者 | White, M.A, Tsalkova, T.N, Mei, F.C, Liu, T, Woods, V.L, Cheng, X. | | 登録日 | 2012-05-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP.
Plos One, 7, 2012
|
|
4R8H
 | | The role of protein-ligand contacts in allosteric regulation of the Escherichia coli Catabolite Activator Protein | | 分子名称: | 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, GLYCEROL, cAMP-activated global transcriptional regulator CRP | | 著者 | Townsend, P.D, Pohl, E, McLeish, T.C.B, Rodgers, T.L, Glover, L.C, Korhonen, H.J, Wilson, M.R, Hodgson, D.R.W, Cann, M.J. | | 登録日 | 2014-09-02 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein.
J.Biol.Chem., 290, 2015
|
|
3H3Z
 | |
