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4AVC
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BU of 4avc by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP
Descriptor: 1,2-ETHANEDIOL, ACETYL COENZYME *A, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
Authors:Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
Deposit date:2012-05-24
Release date:2012-07-11
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
4AVA
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BU of 4ava by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 from Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ...
Authors:Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
Deposit date:2012-05-24
Release date:2012-07-11
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
4BH9
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BU of 4bh9 by Molmil
A structural model of CAP mutant (T127L and S128I) in the apo state
Descriptor: cAMP-activated global transcriptional regulator CRP
Authors:Tzeng, S.R, Kalodimos, C.G.
Deposit date:2013-03-30
Release date:2013-05-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Allosteric inhibition through suppression of transient conformational states.
Nat. Chem. Biol., 9, 2013
4BHP
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BU of 4bhp by Molmil
A structural model of CAP mutant (T127L and S128I) in cGMP-bound state
Descriptor: CAMP RECEPTOR PROTEIN
Authors:Tzeng, S.R, Kalodimos, C.G.
Deposit date:2013-04-04
Release date:2013-05-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Allosteric Inhibition Through Suppression of Transient Conformational States.
Nat.Chem.Biol., 9, 2013
5I2D
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BU of 5i2d by Molmil
Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo
Descriptor: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Feng, Y, Zhang, Y, Ebright, R.H.
Deposit date:2016-02-08
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.405 Å)
Cite:Structural basis of transcription activation.
Science, 352, 2016
3TNQ
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BU of 3tnq by Molmil
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein kinase, ...
Authors:Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
Deposit date:2011-09-01
Release date:2012-02-01
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (3.097 Å)
Cite:Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
4BYY
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BU of 4byy by Molmil
Apo GlxR
Descriptor: GLYCEROL, PHOSPHATE ION, TRANSCRIPTIONAL REGULATOR, ...
Authors:Pohl, E, Cann, M.J, Townsend, P.D, Money, V.A.
Deposit date:2013-07-21
Release date:2014-07-30
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors.
Plos One, 9, 2014
3TNP
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BU of 3tnp by Molmil
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
Authors:Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
Deposit date:2011-09-01
Release date:2012-02-01
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
4CHW
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BU of 4chw by Molmil
The electron crystallography structure of the cAMP-free potassium channel MloK1
Descriptor: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
Authors:Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
Deposit date:2013-12-04
Release date:2014-01-15
Last modified:2019-04-24
Method:ELECTRON CRYSTALLOGRAPHY (7 Å)
Cite:Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
Nat Commun, 5, 2014
4CHV
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BU of 4chv by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1
Descriptor: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
Authors:Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
Deposit date:2013-12-04
Release date:2014-01-15
Last modified:2019-04-24
Method:ELECTRON CRYSTALLOGRAPHY (7 Å)
Cite:Ligand-Induced Structural Changes in the Cyclic Nucleotide-Modulated Potassium Channel Mlok1
Nat.Commun., 5, 2014
5K7L
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BU of 5k7l by Molmil
Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calmodulin, ...
Authors:Whicher, J.R, MacKinnon, R.
Deposit date:2016-05-26
Release date:2016-08-17
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structure of the voltage-gated K+ channel Eag1 reveals an alternative voltage sensing mechanism.
Science, 353, 2016
4CYD
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BU of 4cyd by Molmil
GlxR bound to cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, PROBABLE EXPRESSION TAG, ...
Authors:Townsend, P.D, Bott, M, Cann, M.J, Pohl, E.
Deposit date:2014-04-10
Release date:2014-12-17
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors.
Plos One, 9, 2014
5JON
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BU of 5jon by Molmil
Crystal structure of the unliganded form of HCN2 CNBD
Descriptor: Maltose-binding periplasmic protein,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, NITRATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Klenchin, V.A, Chanda, B.
Deposit date:2016-05-02
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.042 Å)
Cite:Structure and dynamics underlying elementary ligand binding events in human pacemaking channels.
Elife, 5, 2016
7LFY
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BU of 7lfy by Molmil
Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, SODIUM ION, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-19
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
7LFT
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BU of 7lft by Molmil
Cryo-EM structure of human Apo CNGA1 channel in K+/Ca2+
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, POTASSIUM ION, ...
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-18
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
7LFX
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BU of 7lfx by Molmil
Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+/Ca2+
Descriptor: CALCIUM ION, CYCLIC GUANOSINE MONOPHOSPHATE, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-19
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
7LFW
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BU of 7lfw by Molmil
Cryo-EM structure of human cGMP-bound open CNGA1 channel in K+/Ca2+
Descriptor: CALCIUM ION, CYCLIC GUANOSINE MONOPHOSPHATE, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-18
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
7LG1
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BU of 7lg1 by Molmil
Cryo-EM structure of human cGMP-bound CNGA1_E365Q channel in Na+/Ca2+
Descriptor: CALCIUM ION, CYCLIC GUANOSINE MONOPHOSPHATE, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-19
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
4DIN
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BU of 4din by Molmil
Novel Localization and Quaternary Structure of the PKA RI beta Holoenzyme
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Ilouz, R, Bubis, J, Wu, J, Yim, Y.Y, Deal, M.S, Kornev, A.P, Ma, Y, Blumenthal, D.K, Taylor, S.S.
Deposit date:2012-01-31
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Localization and quaternary structure of the PKA RI Beta holoenzyme
Proc.Natl.Acad.Sci.USA, 109, 2012
6CJU
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BU of 6cju by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cAMP
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel
Authors:Nimigean, C.M, Rheinberger, J.
Deposit date:2018-02-26
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
6CJQ
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BU of 6cjq by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, SthK cyclic nucleotide-gated potassium channel
Authors:Nimigean, C.M, Rheinberger, J.
Deposit date:2018-02-26
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
6DT4
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BU of 6dt4 by Molmil
1.8 Angstrom Resolution Crystal Structure of cAMP-Regulatory Protein from Yersinia pestis in Complex with cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, Cyclic AMP receptor protein
Authors:Minasov, G, Shuvalova, L, Kiryukhina, O, Ritzert, J.T.H, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-06-15
Release date:2018-06-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Cyclic AMP Receptor Protein Regulates Quorum Sensing and Global Gene Expression in Yersinia pestis during Planktonic Growth and Growth in Biofilms.
Mbio, 10, 2019
6EO1
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BU of 6eo1 by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1 (PCO-refined)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Kowal, J, Biyani, N, Chami, M, Scherer, S, Rzepiela, A, Baumgartner, P, Upadhyay, V, Nimigean, C, Stahlberg, H.
Deposit date:2017-10-08
Release date:2017-12-27
Last modified:2018-01-10
Method:ELECTRON CRYSTALLOGRAPHY (4.5 Å)
Cite:High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer.
Structure, 26, 2018
6GYN
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BU of 6gyn by Molmil
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Authors:Shintre, C.A, Pike, A.C.W, Tessitore, A, Young, M, Bushell, S.R, Strain-Damerell, C, Mukhopadhyay, S, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2018-06-30
Release date:2019-05-08
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
To Be Published
6GYO
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BU of 6gyo by Molmil
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, ...
Authors:Shintre, C.A, Pike, A.C.W, Tessitore, A, Young, M, Bushell, S.R, Strain-Damerell, C, Mukhopadhyay, S, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2018-06-30
Release date:2019-05-01
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
To Be Published

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数据于2024-04-24公开中

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