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6UY9
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BU of 6uy9 by Molmil
Crystal structure of the STAC3 tandem SH3 domains - P269R, W284S
Descriptor: 1,2-ETHANEDIOL, SH3 and cysteine-rich domain-containing protein 3, SODIUM ION
Authors:Rufenach, B, Van Petegem, F.
Deposit date:2019-11-12
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
Structure, 28, 2020
1ZX6
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BU of 1zx6 by Molmil
High-resolution crystal structure of yeast Pin3 SH3 domain
Descriptor: Ypr154wp
Authors:Kursula, P, Kursula, I, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M.
Deposit date:2005-06-07
Release date:2006-10-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural genomics of yeast SH3 domains
To be Published
2VVK
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BU of 2vvk by Molmil
Grb2 SH3C (1)
Descriptor: GLYCEROL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Harkiolaki, M, Tsirka, T, Feller, S.M.
Deposit date:2008-06-09
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
3CQT
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BU of 3cqt by Molmil
N53I V55L MUTANT of FYN SH3 DOMAIN
Descriptor: Proto-oncogene tyrosine-protein kinase Fyn
Authors:Neculai, A.M, Zarrine-Afsar, A, Howell, P.L, Davidson, A, Chan, H.S.
Deposit date:2008-04-03
Release date:2008-07-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3TVT
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BU of 3tvt by Molmil
Structural basis for Discs Large interaction with Pins
Descriptor: Disks large 1 tumor suppressor protein, Partner of Inscuteable
Authors:Johnston, C.A, Doe, C.Q, Prehoda, K.E.
Deposit date:2011-09-20
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for Discs Large interaction with Pins
To be Published
4OML
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BU of 4oml by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128R
Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-01-27
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4JJD
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BU of 4jjd by Molmil
Crystal structure of the N114A Abl-SH3 domain mutant at pH4
Descriptor: DI(HYDROXYETHYL)ETHER, SODIUM ION, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A, Martin-Garcia, J.M.
Deposit date:2013-03-07
Release date:2014-03-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the Abl-SH3 domain at pH5
To be Published
4EIK
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BU of 4eik by Molmil
Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12
Descriptor: SODIUM ION, Tyrosine-protein kinase Fyn, VSL12 peptide
Authors:Camara-Artigas, A.
Deposit date:2012-04-05
Release date:2013-04-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex.
Acta Crystallogr F Struct Biol Commun, 72, 2016
4JJC
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BU of 4jjc by Molmil
Crystal structure of the Abl-SH3 domain at pH5
Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A, Martin-Garcia, J.M.
Deposit date:2013-03-07
Release date:2014-03-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the Abl-SH3 domain at pH5
To be Published
7A38
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BU of 7a38 by Molmil
Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 6.0
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
Authors:Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
Deposit date:2020-08-18
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 6.0
To be published
2O9V
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BU of 2o9v by Molmil
The second SH3 domain from Ponsin in complex with the paxillin proline rich region
Descriptor: Paxillin, Ponsin
Authors:Pinotsis, N, Wilmanns, M.
Deposit date:2006-12-14
Release date:2007-10-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Paxillin and ponsin interact in nascent costameres of muscle cells
J.Mol.Biol., 369, 2007
6UY8
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BU of 6uy8 by Molmil
Crystal structure of the STAC3 tandem SH3 domains - P269R, K329N
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SH3 and cysteine-rich domain-containing protein 3
Authors:Rufenach, B, Van Petegem, F.
Deposit date:2019-11-12
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
Structure, 28, 2020
7PVR
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BU of 7pvr by Molmil
Crystal structure of the Abl SH3 domain V73E-A74S-S75R-G76T-D77E-G92N-Y93N-N94T-H95E mutant in the space group P41
Descriptor: Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A, Salinas Garcia, M.C.
Deposit date:2021-10-05
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The effect of the hinge loops composition in the domain swapping of the SH3 domain
To be published
1BBZ
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BU of 1bbz by Molmil
CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH A DESIGNED HIGH-AFFINITY PEPTIDE LIGAND: IMPLICATIONS FOR SH3-LIGAND INTERACTIONS
Descriptor: ABL TYROSINE KINASE, PEPTIDE P41, SULFATE ION
Authors:Pisabarro, M.T, Serrano, L, Wilmanns, M.
Deposit date:1998-04-28
Release date:1998-11-25
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions.
J.Mol.Biol., 281, 1998
5EC7
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BU of 5ec7 by Molmil
Crystal structure of a chimeric c-Src-SH3 domain with the sequence of the RT-loop from the Abl-SH3 domain at pH 5.0
Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2015-10-20
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of a chimeric c-Src-SH3 domain with the sequence of the RT-loop from the Abl-SH3 domain at pH 5.0
to be published
7A39
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BU of 7a39 by Molmil
Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 7.0
Descriptor: Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
Authors:Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
Deposit date:2020-08-18
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 7.0
To be published
4JJB
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BU of 4jjb by Molmil
Crystal structure of the Abl-SH3 domain at pH3
Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A, Martin-Garcia, J.M.
Deposit date:2013-03-07
Release date:2014-03-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the Abl-SH3 domain at pH3
To be Published
3FJ5
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BU of 3fj5 by Molmil
Crystal structure of the c-src-SH3 domain
Descriptor: ACETATE ION, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
Authors:Camara-Artigas, A.
Deposit date:2008-12-14
Release date:2009-03-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Intertwined dimeric structure for the SH3 domain of the c-Src tyrosine kinase induced by polyethylene glycol binding
Febs Lett., 583, 2009
5H0B
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BU of 5h0b by Molmil
Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor (S)-2-(((1r,4S)-4-(4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-4-methylpentanoic acid
Descriptor: (2~{S})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]azaniumyl]-4-methyl-pentanoate, Tyrosine-protein kinase HCK
Authors:Tomabechi, Y, Kukimoto-Niino, M, Shirouzu, M.
Deposit date:2016-10-04
Release date:2017-10-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.
Bioorg. Med. Chem., 25, 2017
7A30
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BU of 7a30 by Molmil
Intertwined dimer of the c-Src SH3 domain mutant Q128E
Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ...
Authors:Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
Deposit date:2020-08-18
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Intertwined dimer of the c-Src SH3 domain mutant Q128E
To be published
1YP5
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BU of 1yp5 by Molmil
Yeast Myo5 SH3 domain, tetragonal crystal form
Descriptor: Myosin-5 isoform
Authors:Gonfloni, S, Kursula, P, Sacco, R, Cesareni, G, Wilmanns, M.
Deposit date:2005-01-29
Release date:2006-01-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Yeast Myo5 SH3 domain, tetragonal crystal form
To be Published
1GCQ
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BU of 1gcq by Molmil
CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE
Authors:Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F.
Deposit date:2000-08-08
Release date:2001-08-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
6XVN
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BU of 6xvn by Molmil
Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 1
Descriptor: Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Plaza-Garrido, M.
Deposit date:2020-01-22
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XVO
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BU of 6xvo by Molmil
Crystal structure of the intertwined dimer of the c-Src SH3 domain without ATCUN motif
Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
Authors:Camara-Artigas, A, Plaza-Garrido, M.
Deposit date:2020-01-22
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
1NG2
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BU of 1ng2 by Molmil
Structure of autoinhibited p47phox
Descriptor: Neutrophil cytosolic factor 1
Authors:Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K.
Deposit date:2002-12-16
Release date:2003-05-20
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Cell(Cambridge,Mass.), 113, 2003

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