5OOW
| Crystal structure of lobe II from the nucleotide binding domain of DnaK in complex with AMPPCP | 分子名称: | Chaperone protein DnaK, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Jakob, R.P, Bauer, D, Meinhold, S, Stigler, J, Merkel, U, Maier, T, Rief, M, Zoldak, G. | 登録日 | 2017-08-09 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A folding nucleus and minimal ATP binding domain of Hsp70 identified by single-molecule force spectroscopy. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2KHO
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1BPR
| NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, MINIMIZED AVERAGE STRUCTURE | 分子名称: | DNAK | 著者 | Wang, H, Kurochkin, A.V, Pang, Y, Hu, W, Flynn, G.C, Zuiderweg, E.R.P. | 登録日 | 1998-08-11 | 公開日 | 1999-03-02 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction. Biochemistry, 37, 1998
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6HAB
| Crystal structure of BiP V461F (apo) | 分子名称: | DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP | 著者 | Yan, Y, Ron, D. | 登録日 | 2018-08-07 | 公開日 | 2019-02-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP. Nat Commun, 10, 2019
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1DKZ
| THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 1 NATIVE CRYSTALS | 分子名称: | SUBSTRATE BINDING DOMAIN OF DNAK, SUBSTRATE PEPTIDE (7 RESIDUES) | 著者 | Zhu, X, Zhao, X, Burkholder, W.F, Gragerov, A, Ogata, C.M, Gottesman, M.E, Hendrickson, W.A. | 登録日 | 1996-06-03 | 公開日 | 1996-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural analysis of substrate binding by the molecular chaperone DnaK. Science, 272, 1996
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4R5K
| Crystal structure of the DnaK C-terminus (Dnak-SBD-B) | 分子名称: | CALCIUM ION, Chaperone protein DnaK, SULFATE ION | 著者 | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | 登録日 | 2014-08-21 | 公開日 | 2014-09-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7469 Å) | 主引用文献 | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
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4R5J
| Crystal structure of the DnaK C-terminus (Dnak-SBD-A) | 分子名称: | CALCIUM ION, Chaperone protein DnaK, PHOSPHATE ION | 著者 | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | 登録日 | 2014-08-21 | 公開日 | 2014-09-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.361 Å) | 主引用文献 | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
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4R5L
| Crystal structure of the DnaK C-terminus (Dnak-SBD-C) | 分子名称: | CALCIUM ION, Chaperone protein DnaK, PHOSPHATE ION, ... | 著者 | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | 登録日 | 2014-08-21 | 公開日 | 2014-09-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.9701 Å) | 主引用文献 | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
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4R5I
| Crystal structure of the DnaK C-terminus with the substrate peptide NRLLLTG | 分子名称: | Chaperone protein DnaK, HSP70/DnaK Substrate Peptide: NRLLLTG, PHOSPHATE ION, ... | 著者 | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | 登録日 | 2014-08-21 | 公開日 | 2014-09-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9702 Å) | 主引用文献 | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
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4R5G
| Crystal structure of the DnaK C-terminus with the inhibitor PET-16 | 分子名称: | Chaperone protein DnaK, triphenyl(phenylethynyl)phosphonium | 著者 | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | 登録日 | 2014-08-21 | 公開日 | 2014-09-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.4501 Å) | 主引用文献 | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
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1U00
| HscA substrate binding domain complexed with the IscU recognition peptide ELPPVKIHC | 分子名称: | Chaperone protein hscA, IscU recognition peptide | 著者 | Cupp-Vickery, J.R, Peterson, J.C, Ta, D.T, Vickery, L.E. | 登録日 | 2004-07-12 | 公開日 | 2004-10-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of the Molecular Chaperone HscA Substrate Binding Domain Complexed with the IscU Recognition Peptide ELPPVKIHC. J.Mol.Biol., 342, 2004
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6NHK
| Mortalin nucleotide binding domain in the ADP-bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Page, R.C, Moseng, M.A, Nix, J.C. | 登録日 | 2018-12-23 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.777 Å) | 主引用文献 | Biophysical Consequences of EVEN-PLUS Syndrome Mutations for the Function of Mortalin. J.Phys.Chem.B, 123, 2019
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7Q4R
| Crystal structure of human HSP72-NBD in complex with fragment 1 | 分子名称: | 4-(4-phenyl-1,3-thiazol-2-yl)piperazine-1-carboxamide, Heat shock 70 kDa protein 1A, MAGNESIUM ION, ... | 著者 | Le Bihan, Y.V, Westwood, I.M, van Montfort, R.L.M. | 登録日 | 2021-11-02 | 公開日 | 2022-02-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70. Molecules, 27, 2022
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7PLK
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6S02
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6RZQ
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6P2U
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7RAX
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6PMT
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6SR6
| Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein, ... | 著者 | Valentin Gese, G, Lapouge, K, Kopp, J, Sinning, I. | 登録日 | 2019-09-05 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb. Nat Commun, 11, 2020
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1YUW
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5TKY
| Crystal structure of the co-translational Hsp70 chaperone Ssb in the ATP-bound, open conformation | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein | 著者 | Gumiero, A, Gese, G.V, Weyer, F.A, Lapouge, K, Sinning, I. | 登録日 | 2016-10-10 | 公開日 | 2016-11-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain. Nat Commun, 7, 2016
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2BUP
| T13G Mutant of the ATPASE fragment of Bovine HSC70 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | 著者 | Sousa, M.C, Mckay, D.B. | 登録日 | 1998-09-08 | 公開日 | 1998-09-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change. Biochemistry, 37, 1998
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5UMB
| Crystal structure of ATPase domain of Malaria GRP78 with ADP bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone DnaK, MAGNESIUM ION, ... | 著者 | Chen, Y, Antoshchenko, T, Pizarro, J.C, Song, J.H, Park, H. | 登録日 | 2017-01-26 | 公開日 | 2022-07-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Repurposing drugs to target the malaria parasite unfolding protein response. Sci Rep, 8, 2018
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2BPR
| NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES | 分子名称: | DNAK | 著者 | Wang, H, Kurochkin, A.V, Pang, Y, Hu, W, Flynn, G.C, Zuiderweg, E.R.P. | 登録日 | 1998-08-11 | 公開日 | 1999-03-02 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction. Biochemistry, 37, 1998
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