PDB: 495 resultsInfo pagesStatus searchChemie searchBIRD

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4IZA	Structure of Dually Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain Descriptor: Astrocytic phosphoprotein PEA-15, Mitogen-activated protein kinase 1 Authors: Mace, P.D, Robinson, H, Riedl, S.J. Deposit date: 2013-01-29 Release date: 2013-04-10 Last modified: 2013-04-24 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nat Commun, 4, 2013
4IZ7	Structure of Non-Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain Descriptor: Astrocytic phosphoprotein PEA-15, Mitogen-activated protein kinase 1, SODIUM ION Authors: Mace, P.D, Robinson, H, Riedl, S.J. Deposit date: 2013-01-29 Release date: 2013-04-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nat Commun, 4, 2013
4IZ5	Structure of the complex between ERK2 phosphomimetic mutant and PEA-15 Descriptor: ADENOSINE-5'-DIPHOSPHATE, Astrocytic phosphoprotein PEA-15, Mitogen-activated protein kinase 1, ... Authors: Mace, P.D, Robinson, H, Riedl, S.J. Deposit date: 2013-01-29 Release date: 2013-04-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.19 Å) Cite: Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nat Commun, 4, 2013
4I5H	Crystal Structure of a Double Mutant Rat Erk2 Complexed With a Type II Quinazoline Inhibitor Descriptor: Mitogen-activated protein kinase 1, N-{3-[2-(cyclopropylamino)quinazolin-6-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide Authors: Hari, S.B, Maly, D.J, Merritt, E.A. Deposit date: 2012-11-28 Release date: 2013-07-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Sequence determinants of a specific inactive protein kinase conformation. Chem.Biol., 20, 2013
4H3Q	Crystal structure of human ERK2 complexed with a MAPK docking peptide Descriptor: Dual specificity mitogen-activated protein kinase kinase 2, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Gogl, G, Toeroe, I, Remenyi, A. Deposit date: 2012-09-14 Release date: 2013-02-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Protein-peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinase Acta Crystallogr.,Sect.D, 69, 2013
4H3P	Crystal structure of human ERK2 complexed with a MAPK docking peptide Descriptor: Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-1 Authors: Gogl, G, Toeroe, I, Remenyi, A. Deposit date: 2012-09-14 Release date: 2013-02-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Protein-peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinase Acta Crystallogr.,Sect.D, 69, 2013
4GVA	ADP-bound form of the ERK2 kinase Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Mitogen-activated protein kinase 1 Authors: Pozharski, E, Zhang, J, Shapiro, P. Deposit date: 2012-08-30 Release date: 2012-09-12 Method: X-RAY DIFFRACTION (1.83 Å) Cite: ADP-bound form of the ERK2 kinase TO BE PUBLISHED
4GT3	ATP-bound form of the ERK2 kinase Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Pozharski, E, Zhang, J, Shapiro, P. Deposit date: 2012-08-28 Release date: 2012-09-12 Method: X-RAY DIFFRACTION (1.68 Å) Cite: ATP-bound form of the ERK2 kinase TO BE PUBLISHED
4GSB	Monoclinic crystal form of the apo-ERK2 Descriptor: GLYCEROL, Mitogen-activated protein kinase 1, SULFATE ION, ... Authors: Pozharski, E, Zhang, J, Shapiro, P. Deposit date: 2012-08-27 Release date: 2012-09-12 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Monoclinic crystal form of the apo-ERK2 TO BE PUBLISHED
4G6O	Crystal Structure of the ERK2 Descriptor: 1,2-ETHANEDIOL, 4-{4-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide, Mitogen-activated protein kinase 1, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-07-19 Release date: 2012-09-19 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of the ERK2 complexed with E28 to be published
4G6N	Crystal Structure of the ERK2 Descriptor: 3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1H-indazole, Mitogen-activated protein kinase 1, SULFATE ION Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-07-19 Release date: 2012-09-19 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of the ERK2 complexed with EK0 to be published
4FV9	Crystal Structure of the ERK2 complexed with E71 Descriptor: 1,2-ETHANEDIOL, 3-[4-(2,3-difluorophenyl)-1,2-oxazol-5-yl]-5-(pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine, Mitogen-activated protein kinase 1, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Crystal Structure of the ERK2 complexed with E71 TO BE PUBLISHED
4FV8	Crystal Structure of the ERK2 complexed with E63 Descriptor: 1,2-ETHANEDIOL, 6-({4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]-5-(phenylamino)pyrimidin-2-yl}amino)-1,2-dihydro-3H-indazol-3-one, Mitogen-activated protein kinase 1, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of the ERK2 complexed with E63 TO BE PUBLISHED
4FV7	Crystal Structure of the ERK2 complexed with E94 Descriptor: 1,2-ETHANEDIOL, 4-(3-chlorophenyl)-5-{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}-2-{[2-(piperidin-1-yl)ethyl]amino}thiophene-3-carbonitrile, GLYCEROL, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structure of the ERK2 complexed with E94 TO BE PUBLISHED
4FV6	Crystal Structure of the ERK2 complexed with E57 Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-4-(2-{[(2S)-1-hydroxybutan-2-yl]amino}-5-methylpyrimidin-4-yl)-1H-pyrrole-2-carboxamide, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of the ERK2 complexed with E57 TO BE PUBLISHED
4FV5	Crystal Structure of the ERK2 complexed with EK9 Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, N-[(1S)-2-hydroxy-1-phenylethyl]-4-(5-methyl-2-phenylpyrimidin-4-yl)-1H-pyrrole-2-carboxamide, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal Structure of the ERK2 complexed with EK9 TO BE PUBLISHED
4FV4	Crystal Structure of the ERK2 complexed with EK7 Descriptor: 9-(dimethylamino)-2-[(3-hydroxyphenyl)amino]-5,6-dihydrothieno[3,4-h]quinazoline-7-carbonitrile, GLYCEROL, Mitogen-activated protein kinase 1, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of the ERK2 complexed with EK7 TO BE PUBLISHED
4FV3	Crystal Structure of the ERK2 complexed with EK6 Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of the ERK2 complexed with EK6 TO BE PUBLISHED
4FV2	Crystal Structure of the ERK2 complexed with EK5 Descriptor: 1,2-ETHANEDIOL, 4-[4-(3-chlorophenyl)-1H-pyrazol-5-yl]-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide, GLYCEROL, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of the ERK2 complexed with EK5 TO BE PUBLISHED
4FV1	Crystal Structure of the ERK2 complexed with EK4 Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Mitogen-activated protein kinase 1, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-28 Release date: 2012-08-22 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Crystal Structure of the ERK2 complexed with EK4 TO BE PUBLISHED
4FV0	Crystal Structure of the ERK2 complexed with EK3 Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Mitogen-activated protein kinase 1, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-28 Release date: 2012-08-22 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structure of the ERK2 complexed with EK3 TO BE PUBLISHED
4FUY	Crystal Structure of the ERK2 complexed with EK2 Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-28 Release date: 2012-08-22 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of the ERK2 complexed with EK2 TO BE PUBLISHED
4FUX	Crystal Structure of the ERK2 complexed with E75 Descriptor: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-28 Release date: 2012-08-22 Last modified: 2014-09-24 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of the ERK2 complexed with E75 TO BE PUBLISHED
4FMQ	Crystal structure of human ERK2 complexed with a MAPK docking peptide Descriptor: MAPK DOCKING PEPTIDE, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Gogl, G, Toeroe, I, Remenyi, A. Deposit date: 2012-06-18 Release date: 2012-10-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.098 Å) Cite: Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove. Sci.Signal., 5, 2012
4E92	Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With Inhibitor BM4 Descriptor: 3-{5-[3-ethyl-5-(5-methylfuran-2-yl)-1H-pyrazol-1-yl]-1-[(6-oxo-1,6-dihydropyridin-3-yl)methyl]-1H-benzimidazol-2-yl}-4-hydroxybenzoic acid, 4-{2-[5-(3-chlorophenyl)-1H-pyrazol-4-yl]-1-[3-(1H-imidazol-1-yl)propyl]-1H-benzimidazol-5-yl}benzoic acid, Gag protein Authors: Lemke, C.T. Deposit date: 2012-03-20 Release date: 2012-04-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein. J.Virol., 86, 2012

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