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6B2G
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BU of 6b2g by Molmil
P38A mutant of HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-20
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.407 Å)
主引用文献Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
6AYA
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BU of 6aya by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with Nup153 peptide
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ...
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
6AY9
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BU of 6ay9 by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide
分子名称: CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein, ...
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
6AXY
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BU of 6axy by Molmil
Structure of the V11I/T58A/I124A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6AXX
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BU of 6axx by Molmil
Structure of the T58A/I124A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6AXW
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BU of 6axw by Molmil
Structure of the I124A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation.
MBio, 9, 2018
6AXV
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BU of 6axv by Molmil
Structure of the T58S/T107I/P122A mutant of the HIV-1 capsid protein in complex with PF-3450074 (PF74)
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ...
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6AXT
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BU of 6axt by Molmil
Structure of the T58S/T107I/P122A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6AXS
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BU of 6axs by Molmil
Structure of the V11I/T58A/P122A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6AXR
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BU of 6axr by Molmil
Structure of the P122A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation.
MBio, 9, 2018
6ATE
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BU of 6ate by Molmil
SRC kinase bound to covalent inhibitor
分子名称: N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide, Proto-oncogene tyrosine-protein kinase Src
著者Gurbani, D, Westover, K.D.
登録日2017-08-28
公開日2019-02-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome.
Cell Chem Biol, 26, 2019
5YWC
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BU of 5ywc by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2018-06-13
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWA
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BU of 5ywa by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A)
分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2018-06-13
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW9
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BU of 5yw9 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A)
分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2018-06-13
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW8
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BU of 5yw8 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A)
分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2018-06-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YT3
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BU of 5yt3 by Molmil
Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 S218D and S222D mutant
分子名称: MAGNESIUM ION, Mitogen-activated protein kinase kinase 1, isoform CRA_d, ...
著者Nakae, S, Doko, K, Tada, T, Shirai, T.
登録日2017-11-16
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 S218D and S222D mutant
To Be Published
5YKG
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BU of 5ykg by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (Class2 at 4.57A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2018-06-13
実験手法ELECTRON MICROSCOPY (4.57 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YKF
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BU of 5ykf by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (3D class1 at 4.33A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.33 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YKE
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BU of 5yke by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2018-06-13
実験手法ELECTRON MICROSCOPY (4.11 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YI4
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BU of 5yi4 by Molmil
Solution Structure of the DISC1/Ndel1 complex
分子名称: Disrupted in schizophrenia 1 homolog,Nuclear distribution protein nudE-like 1
著者Ye, F, Yu, C, Yu, C, Zhang, M.
登録日2017-10-02
公開日2017-11-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis.
Neuron, 96, 2017
5WVC
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BU of 5wvc by Molmil
Structure of the CARD-CARD disk
分子名称: Apoptotic protease-activating factor 1, Caspase, IODIDE ION
著者Lin, S.C, Lo, Y.C, Su, T.W.
登録日2016-12-24
公開日2017-04-19
実験手法X-RAY DIFFRACTION (2.993 Å)
主引用文献Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome.
Structure, 25, 2017
5WUA
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BU of 5wua by Molmil
Structure of a Pancreatic ATP-sensitive Potassium Channel
分子名称: ATP-sensitive inward rectifier potassium channel 11,superfolder GFP, SUR1
著者Li, N, Wu, J.-X, Chen, L, Gao, N.
登録日2016-12-16
公開日2017-01-25
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Structure of a Pancreatic ATP-Sensitive Potassium Channel
Cell, 168, 2017
5WP1
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BU of 5wp1 by Molmil
Complex of ERK2 with 5,7-dihydroxychromone
分子名称: 5,7-dihydroxy-4H-1-benzopyran-4-one, BENZOIC ACID, Mitogen-activated protein kinase 1, ...
著者Kurinov, I, Malakhova, M.
登録日2017-08-03
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Multiple phytochemicals at low doses accumulatively inhibit one key protein in cancers
To Be Published
5W4Q
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BU of 5w4q by Molmil
Structure of the R18A/E28A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, Capsid protein p24, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-06-12
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.285 Å)
主引用文献Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket.
MBio, 10, 2019
5W4P
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BU of 5w4p by Molmil
Structure of the E28A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, Capsid protein p24, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-06-12
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket.
MBio, 10, 2019

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件を2024-05-15に公開中

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