PDB: 316 件ウェブページステータス検索Chemie searchBIRD

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6WPA	Structure of AvaR1 bound to DNA half-site 分子名称: AvaR1, PAL2-1-5'-GC 著者 Kapoor, I, Olivares, P.J, Nair, S.K. 登録日 2020-04-26 公開日 2020-07-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones. Elife, 9, 2020
4IVZ	A Y37F mutant of C.Esp1396I bound to its highest affinity operator site OM 分子名称: DNA (5'-D(*AP*TP*GP*TP*AP*GP*AP*CP*TP*AP*TP*AP*GP*TP*CP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*TP*GP*TP*CP*GP*AP*CP*TP*AP*TP*AP*GP*TP*CP*TP*AP*CP*A)-3'), Regulatory protein 著者 Martin, R.N.A, McGeehan, J.E, Kneale, G.G. 登録日 2013-01-23 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I. Plos One, 9, 2014
5W43	Structure of the two-component response regulator RcsB-DNA complex 分子名称: DNA (5'-D(*GP*AP*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*TP*CP*TP*TP*AP*GP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*CP*TP*AP*AP*GP*AP*TP*TP*TP*TP*TP*CP*CP*TP*AP*AP*AP*TP*C)-3'), Transcriptional regulatory protein RcsB 著者 Filippova, E.V, Warwzak, Z, Pshenychnyi, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-06-09 公開日 2018-03-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB. MBio, 9, 2018
5IUL	Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM) and BeF3 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... 著者 Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. 登録日 2016-03-18 公開日 2016-12-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.153 Å) 主引用文献 Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5, 2016
5IUM	Crystal structure of phosphorylated DesKC 分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... 著者 Trajtenberg, F, Buschiazzo, A. 登録日 2016-03-18 公開日 2016-12-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.162 Å) 主引用文献 Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5, 2016
4F2H	Structure of the minimal Ste5 VWA domain subject to autoinhibition by the Ste5 PH domain 分子名称: Protein STE5 著者 Coyle, S.M, Zalatan, J.G, Lim, W.A. 登録日 2012-05-07 公開日 2012-08-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.192 Å) 主引用文献 Conformational control of the Ste5 scaffold protein insulates against MAP kinase misactivation. Science, 337, 2012
4YWL	Pyrococcus furiosus MCM N-terminal domain F179A point mutant pentameric ring 分子名称: Cell division control protein 21, SULFATE ION, ZINC ION 著者 Froelich, C.A, Enemark, E.J. 登録日 2015-03-20 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 MCM ring hexamerization is a prerequisite for DNA-binding. Nucleic Acids Res., 43, 2015
5IUJ	Crystal structure of the DesK-DesR complex in the phosphotransfer state with low Mg2+ (20 mM) 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... 著者 Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. 登録日 2016-03-18 公開日 2016-12-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5, 2016
4EKW	Crystal structure of the NavAb voltage-gated sodium channel (wild-type, 3.2 A) 分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, PHOSPHATE ION 著者 Payandeh, J, Gamal El-Din, T.M, Scheuer, T, Zheng, N, Catterall, W.A. 登録日 2012-04-10 公開日 2012-05-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Crystal structure of a voltage-gated sodium channel in two potentially inactivated states. Nature, 486, 2012
6PH4	Full length LOV-PAS-HK construct from the LOV-HK sensory protein from Brucella abortus (light-adapted, construct 15-489) 分子名称: Blue-light-activated histidine kinase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... 著者 Rinaldi, J, Otero, L.H, Fernandez, I, Goldbaum, F.A, Shin, H, Yang, X, Klinke, S. 登録日 2019-06-25 公開日 2020-12-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase. Mbio, 12, 2021
4CB0	Crystal structure of CpxAHDC in complex with ATP (hexagonal form) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, SENSOR PROTEIN CPXA, SULFATE ION 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-10-09 公開日 2014-02-12 最終更新日 2017-07-12 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
6ZXM	Diguanylate cyclase DgcR in complex with c-di-GMP 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Putative GGDEF/response regulator receiver domain protein 著者 Teixeira, R.D, Schirmer, T. 登録日 2020-07-29 公開日 2021-03-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase. Nat Commun, 12, 2021
3V9F	Crystal Structure of the extracellular domain of the putative hybrid two component system BT3049 from B. thetaiotaomicron 分子名称: Two-component system sensor histidine kinase/response regulator, hybrid (One-component system) 著者 Zhang, Z, Liu, Q, Hendrickson, W.A. 登録日 2011-12-27 公開日 2012-03-14 最終更新日 2014-10-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structures of apparent saccharide sensors from histidine kinase receptors prevalent in a human gut symbiont. Febs J., 281, 2014
5GUX	Cytochrome c-dependent nitric oxide reductase (cNOR) from Pseudomonas aeruginosa in complex with xenon 分子名称: Antibody fab fragment heavy chain, Antibody fab fragment light chain, CALCIUM ION, ... 著者 Ishii, S, Terasaka, E, Sugimoto, H, Shiro, Y, Tosha, T. 登録日 2016-08-31 公開日 2017-08-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Dynamics of nitric oxide controlled by protein complex in bacterial system. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7QHS	S. cerevisiae CMGE nucleating origin DNA melting 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ... 著者 Lewis, J.S, Sousa, J.S, Costa, A. 登録日 2021-12-14 公開日 2022-06-15 最終更新日 2022-07-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Mechanism of replication origin melting nucleated by CMG helicase assembly. Nature, 606, 2022
4BIY	Crystal structure of CpxAHDC (monoclinic form 2) 分子名称: ADENOSINE-5'-DIPHOSPHATE, SENSOR PROTEIN CPXA, SULFATE ION 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-04-13 公開日 2014-02-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
4GZ8	Mouse Semaphorin 3A, domains Sema-PSI-IG 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 Janssen, B.J.C, Malinauskas, T, Siebold, C, Jones, E.Y. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex. Nat.Struct.Mol.Biol., 19, 2012
3UM7	Crystal structure of the human two pore domain K+ ion channel TRAAK (K2P4.1) 分子名称: POTASSIUM ION, Potassium channel subfamily K member 4 著者 Brohawn, S.G, MacKinnon, R. 登録日 2011-11-12 公開日 2012-02-08 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel. Science, 335, 2012
6CJE	Crystal Structure of Mnk2-D228G in complex with Inhibitor 分子名称: 4-[(9H-purin-6-yl)amino]benzamide, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION 著者 Han, Q. 登録日 2018-02-26 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.36 Å) 主引用文献 Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
6CJW	Crystal Structure of Mnk2-D228G in Complex With Inhibitor 分子名称: 3-(pyridin-4-yl)imidazo[1,2-b]pyridazine, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION 著者 Han, Q. 登録日 2018-02-27 公開日 2018-05-09 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
4BIV	Crystal structure of CpxAHDC (trigonal form) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, SENSOR PROTEIN CPXA 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-04-13 公開日 2014-02-12 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
3TPQ	Crystal structure of wild-type MAL RPEL domain in complex with five G-actins 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
4Q2A	WNK1: A chloride sensor via autophosphorylation 分子名称: BROMIDE ION, Serine/threonine-protein kinase WNK1 著者 Piala, A, Moon, T, Akella, R, He, H, Cobb, M.H, Goldsmith, E. 登録日 2014-04-07 公開日 2014-05-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Chloride Sensing by WNK1 Involves Inhibition of Autophosphorylation. Sci.Signal., 7, 2014
4AK3	Crystal structure of Human fibrillar procollagen type III C- propeptide trimer 分子名称: CALCIUM ION, COLLAGEN ALPHA-1(III) CHAIN 著者 Bourhis, J.M, Mariano, N, Zhao, Y, Harlos, K, Jones, E.Y, Moali, C, Aghajari, N, Hulmes, D.J.S. 登録日 2012-02-21 公開日 2012-09-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural Basis of Fibrillar Collagen Trimerization and Related Genetic Disorders. Nat.Struct.Mol.Biol., 19, 2012
6CJH	Co-crystal structure of MNK2 in complex with an inhibitor 分子名称: 3-phenyl-5-(pyridin-4-yl)-1H-indazole, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION 著者 Han, Q. 登録日 2018-02-26 公開日 2018-05-09 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018

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