PDB: 36 resultsInfo pagesStatus searchChemie searchBIRD

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2I0Y	cFMS tyrosine kinase (FGF KID) in complex with an arylamide inhibitor Descriptor: 5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE, cFMS Tyrosine Kinase Authors: Schubert, C, Schalk-Hihi, C. Deposit date: 2006-08-11 Release date: 2006-11-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors. J.Biol.Chem., 282, 2007
2I0V	c-FMS tyrosine kinase in complex with a quinolone inhibitor Descriptor: 6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE, SULFATE ION, cFMS tyrosine kinase Authors: Schubert, C, Schalk-Hihi, C. Deposit date: 2006-08-11 Release date: 2006-11-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors. J.Biol.Chem., 282, 2007
2PWL	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549H Mutation Responsible for Crouzon Syndrome. Descriptor: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-11 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2PVF	Crystal Structure of Tyrosine Phosphorylated Activated FGF Receptor 2 (FGFR2) Kinase Domain in Complex with ATP Analog and Substrate Peptide Descriptor: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-09 Release date: 2007-09-25 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2PZ5	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549T Mutation Responsible for Pfeiffer Syndrome Descriptor: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-17 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2PSQ	Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain Descriptor: Fibroblast growth factor receptor 2, SULFATE ION Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-07 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2PVY	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome. Descriptor: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-10 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2PZR	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome Descriptor: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-18 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2PY3	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565G Mutation Responsible for Pfeiffer Syndrome Descriptor: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-15 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2Q0B	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565A Mutation Responsible for Pfeiffer Syndrome Descriptor: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-21 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2PZP	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K526E Mutation Responsible for Crouzon Syndrome Descriptor: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... Authors: Chen, H, Mohammadi, M. Deposit date: 2007-05-18 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007

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