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8XK5
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BU of 8xk5 by Molmil
SNB1G11 Fab bound to SFTSV glycoprotein Gn
Descriptor: Envelopment polyprotein, mAb SNB1G11 Fab heavy chain, mAb SNB1G11 Fab light chain
Authors:Deng, Z.
Deposit date:2023-12-22
Release date:2024-07-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:A broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
Nat Commun, 15, 2024
5YM3
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BU of 5ym3 by Molmil
CYP76AH1-4pi from salvia miltiorrhiza
Descriptor: 4-PHENYL-1H-IMIDAZOLE, Ferruginol synthase, MANGANESE (II) ION, ...
Authors:Chang, Z.
Deposit date:2017-10-20
Release date:2018-10-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Crystal structure of CYP76AH1 in 4-PI-bound state from Salvia miltiorrhiza.
Biochem.Biophys.Res.Commun., 511, 2019
8XK6
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BU of 8xk6 by Molmil
S2A5 Fab bound to SFTSV glycoprotein Gn
Descriptor: Envelopment polyprotein, mAb S2A5 Fab heavy chain, mAb S2A5 Fab light chain
Authors:Deng, Z.
Deposit date:2023-12-22
Release date:2024-07-10
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
Nat Commun, 15, 2024
3QOB
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BU of 3qob by Molmil
Mechanical Coupling Controls Cooperative Ligand Binding in a Homodimeric Hemoglobin
Descriptor: CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ren, Z.
Deposit date:2011-02-09
Release date:2020-06-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UT6
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BU of 3ut6 by Molmil
Crystal structure of E. Coli PNP complexed with PO4 and formycin A
Descriptor: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type
Authors:Stefanic, Z.
Deposit date:2011-11-25
Release date:2012-05-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A.
Febs Lett., 586, 2012
7DRG
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BU of 7drg by Molmil
Pseudomonas aeruginosa T6SS protein PA0821
Descriptor: PA0821
Authors:She, Z.
Deposit date:2020-12-28
Release date:2021-06-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Pseudomonas aeruginosa PAAR2 cluster encodes a putative VRR-NUC domain-containing effector.
Febs J., 288, 2021
6JDP
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BU of 6jdp by Molmil
the imm52 family protein TsiT (PA3908) from Pseudomonas aeruginosa
Descriptor: Imm52 family protein, PHOSPHATE ION, SODIUM ION
Authors:She, Z.
Deposit date:2019-02-02
Release date:2019-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural characterization of the Imm52 family protein TsiT in Pseudomonas aeruginosa.
Protein Sci., 28, 2019
7DYM
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BU of 7dym by Molmil
Pseudomonas aeruginosa TseT-TsiT complex
Descriptor: Imm52 domain-containing protein, Tox-REase-5 domain-containing protein
Authors:She, Z.
Deposit date:2021-01-22
Release date:2021-08-25
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure and SAXS studies unveiled a novel inhibition mechanism of the Pseudomonas aeruginosa T6SS TseT-TsiT complex.
Int.J.Biol.Macromol., 188, 2021
4U74
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BU of 4u74 by Molmil
Crystal structure of 4-phenylimidazole bound form of human indoleamine 2,3-dioxygenase (G262A mutant)
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 4-PHENYL-1H-IMIDAZOLE, Indoleamine 2,3-dioxygenase 1, ...
Authors:Sugimoto, H, Horitani, M, Kometani, E, Shiro, Y.
Deposit date:2014-07-30
Release date:2015-09-02
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Conformation and Mobility of Active Site Loop is Critical for Substrate Binding and Inhibition in Human Indoleamine 2,3-Dioxygenase
to be published
4U82
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BU of 4u82 by Molmil
Structure of S. aureus undecaprenyl diphosphate synthase in complex with FSPP and sulfate
Descriptor: Isoprenyl transferase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ...
Authors:Zhu, W, Oldfield, E.
Deposit date:2014-07-31
Release date:2015-02-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Antibacterial drug leads: DNA and enzyme multitargeting.
J.Med.Chem., 58, 2015
4U8A
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BU of 4u8a by Molmil
Crystal structure of D(CGCGAATTCGCG)2 complexed with BPH-1503
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, N,N'-bis[3-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]biphenyl-4,4'-dicarboxamide
Authors:Zhu, W, Oldfield, E.
Deposit date:2014-08-01
Release date:2015-02-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Antibacterial drug leads: DNA and enzyme multitargeting.
J.Med.Chem., 58, 2015
4TX4
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BU of 4tx4 by Molmil
Crystal Structure of a Single-Domain Cysteine Protease Inhibitor from Cowpea (Vigna unguiculata)
Descriptor: Cysteine proteinase inhibitor, SULFATE ION
Authors:Pereira, H.M, Valadares, N, Monteiro-Junior, J.E, Carvalho, C.P.S, Grangeiro, T.B.
Deposit date:2014-07-02
Release date:2015-10-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Expression in Escherichia coli of cysteine protease inhibitors from cowpea (Vigna unguiculata): The crystal structure of a single-domain cystatin gives insights on its thermal and pH stability.
Int. J. Biol. Macromol., 102, 2017
4U21
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BU of 4u21 by Molmil
GluA2flip sLBD complexed with FW and (R,R)-2b crystal form E
Descriptor: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.3908 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
7MMD
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BU of 7mmd by Molmil
Crystal structure of HCV NS3/4A D168A protease in complex with JZ01-19
Descriptor: 1,2-ETHANEDIOL, NS3/4A protease, SULFATE ION, ...
Authors:Zephyr, J, Schiffer, C.A.
Deposit date:2021-04-29
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance.
J.Mol.Biol., 434, 2022
4UY3
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BU of 4uy3 by Molmil
Cytoplasmic domain of bacterial cell division protein ezra
Descriptor: SEPTATION RING FORMATION REGULATOR EZRA
Authors:Cleverley, R.M, Barrett, J.R, Basle, A, Khai-Bui, N, Hewitt, L, Solovyova, A, Xu, Z, Daniela, R.A, Dixon, N.E, Harry, E.J, Oakley, A.J, Vollmer, W, Lewis, R.J.
Deposit date:2014-08-28
Release date:2014-10-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and Function of a Spectrin-Like Regulator of Bacterial Cytokinesis.
Nat.Commun., 5, 2014
4V4T
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BU of 4v4t by Molmil
Crystal structure of the whole ribosomal complex with a stop codon in the A-site.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
Deposit date:2005-10-12
Release date:2014-07-09
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (6.46 Å)
Cite:Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
3JZU
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BU of 3jzu by Molmil
Crystal structure of Dipeptide Epimerase from Enterococcus faecalis V583 complexed with Mg and dipeptide L-Leu-L-Tyr
Descriptor: Dipeptide Epimerase, LEUCINE, MAGNESIUM ION, ...
Authors:Fedorov, A.A, Fedorov, E.V, Imker, H.J, Sakai, A, Gerlt, J.A, Almo, S.C.
Deposit date:2009-09-24
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V6A
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BU of 4v6a by Molmil
Structure of EF-P bound to the 70S ribosome.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Stanley, R.E, Blaha, G.
Deposit date:2009-06-15
Release date:2014-07-09
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome.
Science, 325, 2009
3JXW
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BU of 3jxw by Molmil
Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors
Descriptor: 8-[(E)-2-cyclopropylethenyl]-2-[(dimethylamino)methyl][1]benzothieno[3,2-d]pyrimidin-4(3H)-one, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Stoll, V.S.
Deposit date:2009-09-21
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors
TO BE PUBLISHED
3JAK
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BU of 3jak by Molmil
Cryo-EM structure of GTPgammaS-microtubule co-polymerized with EB3 (merged dataset with and without kinesin bound)
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Zhang, R, Nogales, E.
Deposit date:2015-06-16
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
7NHQ
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BU of 7nhq by Molmil
Structure of PSII-I prime (PSII with Psb28, and Psb34)
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ...
Authors:Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M.
Deposit date:2021-02-11
Release date:2021-05-05
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structural insights into photosystem II assembly.
Nat.Plants, 7, 2021
7NHP
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BU of 7nhp by Molmil
Structure of PSII-I (PSII with Psb27, Psb28, and Psb34)
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ...
Authors:Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M.
Deposit date:2021-02-11
Release date:2021-05-05
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Structural insights into photosystem II assembly.
Nat.Plants, 7, 2021
7NHO
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BU of 7nho by Molmil
Structure of PSII-M
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ...
Authors:Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M.
Deposit date:2021-02-11
Release date:2021-05-05
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Structural insights into photosystem II assembly.
Nat.Plants, 7, 2021
4LF8
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BU of 4lf8 by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S rRNA, MAGNESIUM ION, PAROMOMYCIN, ...
Authors:Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T.
Deposit date:2013-06-26
Release date:2014-07-02
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (3.1484 Å)
Cite:Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
to be published, 2013
3J78
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BU of 3j78 by Molmil
Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class I - non-rotated ribosome with 2 tRNAs)
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
Authors:Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A.
Deposit date:2014-05-29
Release date:2014-08-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014

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