PDB: 48062 resultsInfo pagesStatus searchChemie searchBIRD

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1H9K	Two crystal structures of the cytoplasmic molybdate-binding protein ModG suggest a novel cooperative binding mechanism and provide insights into ligand-binding specificity. Phosphate-grown form with tungstate and phosphate bound Descriptor: MOLYBDENUM-BINDING-PROTEIN, PHOSPHATE ION, TUNGSTATE(VI)ION Authors: Delarbre, L, Stevenson, C.E.M, White, D.J, Mitchenall, L.A, Pau, R.N, Lawson, D.M. Deposit date: 2001-03-13 Release date: 2001-05-11 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Two Crystal Structures of the Cytoplasmic Molybdate-Binding Protein Modg Suggest a Novel Cooperative Binding Mechanism and Provide Insights Into Ligand-Binding Specificity J.Mol.Biol., 308, 2001
6BH3	LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR (S)-N-(1-(3-isopropyl-1H-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropanecarboxamide (Compound N55) Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Horton, J.R, Cheng, X. Deposit date: 2017-10-29 Release date: 2018-03-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.701 Å) Cite: Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A. J. Med. Chem., 61, 2018
6BHR	HIV-1 immature CTD-SP1 hexamer in complex with IP6 Descriptor: Capsid protein p24,Spacer peptide 1, INOSITOL HEXAKISPHOSPHATE Authors: Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O. Deposit date: 2017-10-31 Release date: 2018-08-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.908 Å) Cite: Inositol phosphates are assembly co-factors for HIV-1. Nature, 560, 2018
1KT2	CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, ... Authors: Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J. Deposit date: 2002-01-15 Release date: 2002-05-01 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002
1KLO	CRYSTAL STRUCTURE OF THREE CONSECUTIVE LAMININ-TYPE EPIDERMAL GROWTH FACTOR-LIKE (LE) MODULES OF LAMININ GAMMA1 CHAIN HARBORING THE NIDOGEN BINDING SITE Descriptor: LAMININ Authors: Stetefeld, J, Mayer, U, Timpl, R, Huber, R. Deposit date: 1996-02-02 Release date: 1997-08-20 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of three consecutive laminin-type epidermal growth factor-like (LE) modules of laminin gamma1 chain harboring the nidogen binding site. J.Mol.Biol., 257, 1996
6BN3	CTX-M-151 class A extended-spectrum beta-lactamase apo crystal structure at 1.3 Angstrom resolution Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase Authors: Power, P, Ghiglione, B, Rodriguez, M.M, Gutkind, G, Ishii, Y, Bonomo, R.A, Klinke, S. Deposit date: 2017-11-16 Release date: 2018-11-21 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.278 Å) Cite: Structural and Biochemical Characterization of the Novel CTX-M-151 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam. Antimicrob.Agents Chemother., 65, 2021
6BNP	CryoEM structure of MyosinVI-actin complex in the rigor (nucleotide-free) state Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... Authors: Gurel, P.S, Alushin, G.A. Deposit date: 2017-11-17 Release date: 2018-01-10 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity. Elife, 6, 2017
7FV2	PanDDA analysis group deposition -- PHIP in complex with Z445899798 Descriptor: N-(2-methoxyethyl)-4-(thiophene-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
1GTP	GTP CYCLOHYDROLASE I Descriptor: GTP CYCLOHYDROLASE I, SULFATE ION Authors: Nar, H, Huber, R, Meining, W, Bacher, A. Deposit date: 1995-09-16 Release date: 1996-11-08 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Atomic structure of GTP cyclohydrolase I. Structure, 3, 1995
6BGW	LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid(Compound N41) Descriptor: 2-{(S)-(2-chlorophenyl)[2-(4,4-difluoropiperidin-1-yl)ethoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Horton, J.R, Cheng, X. Deposit date: 2017-10-29 Release date: 2018-03-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.644 Å) Cite: Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A. J. Med. Chem., 61, 2018
7FV1	PanDDA analysis group deposition -- PHIP in complex with Z4912742920 Descriptor: PH-interacting protein, tert-butyl [3-({[4-(furan-2-carbonyl)piperazine-1-carbonyl]amino}methyl)phenyl]carbamate Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FVG	PanDDA analysis group deposition -- PHIP in complex with Z992453336 Descriptor: N-(4-methoxyphenyl)-4-(5-methylfuran-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FVI	PanDDA analysis group deposition -- PHIP in complex with Z183306756 Descriptor: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-(furan-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.18 Å) Cite: PanDDA analysis group deposition To Be Published
7FVJ	PanDDA analysis group deposition -- PHIP in complex with Z4913873236 Descriptor: (2S)-4-(furan-2-carbonyl)-2-methyl-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FV9	PanDDA analysis group deposition -- PHIP in complex with Z1004253138 Descriptor: 4-(5-methylfuran-2-carbonyl)-N-[(thiophen-2-yl)methyl]piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.17 Å) Cite: PanDDA analysis group deposition To Be Published
7FVM	PanDDA analysis group deposition -- PHIP in complex with Z1590917771 Descriptor: 4-(furan-2-carbonyl)-N-(1,2-oxazol-3-yl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.26 Å) Cite: PanDDA analysis group deposition To Be Published
7FVL	PanDDA analysis group deposition -- PHIP in complex with Z4140355932 Descriptor: N-{[(2S)-5,5-dimethyl-1,4-dioxan-2-yl]methyl}-4-(3-hydroxybenzoyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
1HDI	Pig muscle 3-PHOSPHOGLYCERATE KINASE complexed with 3-PG and MgADP. Descriptor: 3-PHOSPHOGLYCERIC ACID, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... Authors: Szilagyi, A.N, Ghosh, M, Garman, E, Vas, M. Deposit date: 2000-11-16 Release date: 2001-02-26 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A 1.8 A resolution structure of pig muscle 3-phosphoglycerate kinase with bound MgADP and 3-phosphoglycerate in open conformation: new insight into the role of the nucleotide in domain closure. J. Mol. Biol., 306, 2001
7FVA	PanDDA analysis group deposition -- PHIP in complex with Z4913872963 Descriptor: (2S)-N-(cyclopropylmethyl)-4-(furan-2-carbonyl)-2-methylpiperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.19 Å) Cite: PanDDA analysis group deposition To Be Published
7FVQ	PanDDA analysis group deposition -- PHIP in complex with Z68576046 Descriptor: N-butyl-4-(thiophene-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FVC	PanDDA analysis group deposition -- PHIP in complex with Z495704106 Descriptor: N-(cyclopropylmethyl)-4-(3,4-dichlorobenzoyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.18 Å) Cite: PanDDA analysis group deposition To Be Published
7FUT	PanDDA analysis group deposition -- PHIP in complex with Z44602357 Descriptor: 4-(furan-2-carbonyl)-N-propylpiperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.18 Å) Cite: PanDDA analysis group deposition To Be Published
7FVP	PanDDA analysis group deposition -- PHIP in complex with Z1004277578 Descriptor: N-butyl-4-(5-methylfuran-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
7FUS	PanDDA analysis group deposition -- PHIP in complex with Z44602363 Descriptor: N-(2-chlorophenyl)-4-(furan-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein Authors: Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. Deposit date: 2023-03-09 Release date: 2023-03-29 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: PanDDA analysis group deposition To Be Published
1M1G	Crystal Structure of Aquifex aeolicus N-utilization substance G (NusG), Space Group P2(1) Descriptor: Transcription antitermination protein nusG Authors: Steiner, T, Kaiser, J.T, Marinkovic, S, Huber, R, Wahl, M.C. Deposit date: 2002-06-19 Release date: 2003-02-04 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities Embo J., 21, 2002

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