6PGC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pgc by Molmil](/molmil-images/mine/6pgc) | |
5XF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xf0 by Molmil](/molmil-images/mine/5xf0) | |
6PG7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pg7 by Molmil](/molmil-images/mine/6pg7) | |
6PGD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pgd by Molmil](/molmil-images/mine/6pgd) | WDR5delta32 bound to peptidomimetic | Descriptor: | N-acetyl-L-alanyl-5-[5-(hydroxymethyl)-1H-imidazol-2-yl]-L-norvalyl-L-valinamide, SULFATE ION, WD repeat-containing protein 5 | Authors: | Dennis, M.L, Peat, T.S. | Deposit date: | 2019-06-24 | Release date: | 2019-12-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Fragment screening for a protein-protein interaction inhibitor to WDR5. Struct Dyn., 6, 2019
|
|
6PGQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pgq by Molmil](/molmil-images/mine/6pgq) | |
6P05
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6p05 by Molmil](/molmil-images/mine/6p05) | Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with compound 27 | Descriptor: | Bromodomain-containing protein 4, GLYCEROL, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(1-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)-1H-indol-4-yl}ethanesulfonamide | Authors: | Ratia, K.M, Xiong, R, Li, Y, Zhao, J, Gutgesell, L.M, Shen, Z, Dye, K, Dubrovyskyii, O, Zhao, H, Huang, F, Tonetti, D.A, Thatcher, G.R. | Deposit date: | 2019-05-16 | Release date: | 2020-05-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib. J.Med.Chem., 63, 2020
|
|
8SHE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8she by Molmil](/molmil-images/mine/8she) | CCT-G beta 5 complex closed state 8 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-13 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SHD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8shd by Molmil](/molmil-images/mine/8shd) | CCT G beta 5 complex closed state 10 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-13 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SHP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8shp by Molmil](/molmil-images/mine/8shp) | CCT G beta 5 complex closed state 13 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-14 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
6PPT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ppt by Molmil](/molmil-images/mine/6ppt) | |
8SGL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sgl by Molmil](/molmil-images/mine/8sgl) | CCT G beta 5 complex closed state 15 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-12 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
6P5V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6p5v by Molmil](/molmil-images/mine/6p5v) | Structure of DCN1 bound to N-((4S,5S)-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-methylbenzamide | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Lysozyme,DCN1-like protein 1 fusion, N-[(4S,5S)-1-[(1S)-cyclohex-3-en-1-yl]-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-3-methylbenzamide | Authors: | Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A. | Deposit date: | 2019-05-31 | Release date: | 2019-09-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.398 Å) | Cite: | Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation. J.Med.Chem., 62, 2019
|
|
8SHA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sha by Molmil](/molmil-images/mine/8sha) | CCT-G beta 5 complex closed state 4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-13 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SHO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sho by Molmil](/molmil-images/mine/8sho) | CCT G beta 5 complex close state 11 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-14 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SFE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sfe by Molmil](/molmil-images/mine/8sfe) | Open state CCT-G beta 5 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-10 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SHT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sht by Molmil](/molmil-images/mine/8sht) | CCT G beta 5 complex closed state 14 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-14 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SHL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8shl by Molmil](/molmil-images/mine/8shl) | CCT G beta 5 complex closed state 5 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-14 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SH9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sh9 by Molmil](/molmil-images/mine/8sh9) | CCT G beta 5 complex best PhLP1 class | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-13 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SFF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sff by Molmil](/molmil-images/mine/8sff) | CCT G beta 5 complex closed state 0 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-11 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SG9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sg9 by Molmil](/molmil-images/mine/8sg9) | CCT G beta 5 complex closed state 3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-12 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SGQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sgq by Molmil](/molmil-images/mine/8sgq) | CCT G beta 5 complex intermediate state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-12 | Release date: | 2023-11-01 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SGC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sgc by Molmil](/molmil-images/mine/8sgc) | CCT G beta 5 complex closed state 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-12 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SHN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8shn by Molmil](/molmil-images/mine/8shn) | CCT-G beta 5 complex closed state 6 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-14 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SG8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sg8 by Molmil](/molmil-images/mine/8sg8) | CCT G beta 5 complex closed state 1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-11 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|
8SHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8shg by Molmil](/molmil-images/mine/8shg) | CCT G beta 5 complex closed state 9 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ... | Authors: | Wang, S, Sass, M, Willardson, B.M, Shen, P.S. | Deposit date: | 2023-04-14 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller. Mol.Cell, 83, 2023
|
|