PDB: 79225 resultsInfo pagesStatus searchChemie searchBIRD

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4QGB	Crystal structure of mutant ribosomal protein G219V TthL1 Descriptor: 50S ribosomal protein L1, ACETATE ION, CHLORIDE ION Authors: Gabdulkhakov, A.G, Nevskaya, N.A, Nikonov, S.V. Deposit date: 2014-05-22 Release date: 2015-02-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions. Acta Crystallogr.,Sect.D, 71, 2015
5YDU	Crystal structure of Utp30 Descriptor: PHOSPHATE ION, Ribosome biogenesis protein UTP30 Authors: Hu, J, Zhu, X, Ye, K. Deposit date: 2017-09-14 Release date: 2017-11-01 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.646 Å) Cite: Structure and RNA recognition of ribosome assembly factor Utp30. RNA, 23, 2017
6MD3	Structure of T. brucei RRP44 PIN domain Descriptor: CHLORIDE ION, MANGANESE (II) ION, Rrp44p homologue, ... Authors: Guimaraes, B.G, Cesaro, G. Deposit date: 2018-09-03 Release date: 2019-01-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Trypanosoma brucei RRP44 is involved in an early stage of large ribosomal subunit RNA maturation. RNA Biol, 16, 2019
5LTA	Crystal structure of the Prp43-ADP-BeF3-U7-RNA complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CACODYLATE ION, ... Authors: Tauchert, M.J, Ficner, R. Deposit date: 2016-09-06 Release date: 2017-01-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.621 Å) Cite: Structural insights into the mechanism of the DEAH-box RNA helicase Prp43. Elife, 6, 2017
6QWL	Influenza B virus (B/Panama/45) polymerase Hetermotrimer in complex with 3'5' cRNA promoter Descriptor: 3' cRNA, 5' cRNA, Polymerase acidic protein, ... Authors: Keown, J.R, Carrique, L, Fan, H, Fodor, E, Grimes, J.M. Deposit date: 2019-03-05 Release date: 2019-09-04 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
6RR7	Influenza A virus (A/NT/60/1968) polymerase Heterotrimer bound to 3'5' vRNA promoter and capped RNA primer Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(M7G))-R(P*AP*AP*UP*CP*U)-3'), ... Authors: Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. Deposit date: 2019-05-17 Release date: 2019-09-04 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
8OST	Structure of human terminal uridylyltransferase 4 (TUT4, ZCCHC11) in complex with pre-let7g miRNA and Lin28A Descriptor: Protein lin-28 homolog A, Terminal uridylyltransferase 4, ZINC ION, ... Authors: Gilbert, R.J, Yi, G, Ye, M. Deposit date: 2023-04-20 Release date: 2024-07-17 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (3.69 Å) Cite: Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs. Nat.Struct.Mol.Biol., 31, 2024
6QX3	Influenza A virus (A/NT/60/1968) polymerase Hetermotrimer in complex with 3'5' cRNA promoter and Nb8205 Descriptor: Nb8205, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. Deposit date: 2019-03-07 Release date: 2019-09-04 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.79 Å) Cite: Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
3EPL	Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: Insight into tRNA recognition and reaction mechanism Descriptor: DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... Authors: Huang, R.H, Zhou, C. Deposit date: 2008-09-29 Release date: 2008-11-04 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: insight into tRNA recognition and reaction mechanism. Proc.Natl.Acad.Sci.Usa, 105, 2008
3EPJ	Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: Insight into tRNA recognition and reaction mechanism Descriptor: MAGNESIUM ION, ZINC ION, tRNA, ... Authors: Huang, R.H, Zhou, C. Deposit date: 2008-09-29 Release date: 2008-11-04 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: insight into tRNA recognition and reaction mechanism. Proc.Natl.Acad.Sci.Usa, 105, 2008
3EPK	Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: Insight into tRNA recognition and reaction mechanism Descriptor: DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, PYROPHOSPHATE, ... Authors: Huang, R.H, Zhou, C. Deposit date: 2008-09-29 Release date: 2008-11-04 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: insight into tRNA recognition and reaction mechanism. Proc.Natl.Acad.Sci.Usa, 105, 2008
3EPH	Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: Insight into tRNA recognition and reaction mechanism Descriptor: MAGNESIUM ION, PYROPHOSPHATE, ZINC ION, ... Authors: Huang, R.H, Zhou, C. Deposit date: 2008-09-29 Release date: 2008-11-04 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: insight into tRNA recognition and reaction mechanism. Proc.Natl.Acad.Sci.Usa, 105, 2008
6QX8	Influenza A virus (A/NT/60/1968) polymerase dimer of heterotrimer in complex with 5' cRNA promoter Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*CP*AP*AP*AP*AP*GP*CP*AP*GP*A)-3'), ... Authors: Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. Deposit date: 2019-03-07 Release date: 2019-09-04 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.07 Å) Cite: Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
9C7A	Crystal structure of R149W neurodevelopmental disease-associated U2AF2 variant Descriptor: DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), GLYCEROL, SODIUM ION, ... Authors: Maji, D, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2024-06-10 Release date: 2024-10-02 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Recurrent Neurodevelopmentally Associated Variants of the Pre-mRNA Splicing Factor U2AF2 Alter RNA Binding Affinities and Interactions. Biochemistry, 63, 2024
9C7B	Crystal structure of R150H neurodevelopmental disease-associated U2AF2 variant Descriptor: DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit Authors: Maji, D, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2024-06-10 Release date: 2024-10-02 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Recurrent Neurodevelopmentally Associated Variants of the Pre-mRNA Splicing Factor U2AF2 Alter RNA Binding Affinities and Interactions. Biochemistry, 63, 2024
6QXE	Influenza A virus (A/NT/60/1968) polymerase dimer of hetermotrimer in complex with 3'5' cRNA promoter and Nb8205 Descriptor: Nb8205, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. Deposit date: 2019-03-07 Release date: 2019-09-04 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (4.15 Å) Cite: Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
1VQ7	The structure of the transition state analogue "DCA" bound to the large ribosomal subunit of haloarcula marismortui Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(5AA)P*(2OP)P*(PAE)P*AP*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ... Authors: Schmeing, T.M, Steitz, T.A. Deposit date: 2004-12-16 Release date: 2005-11-29 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.5 Å) Cite: An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA. Nature, 438, 2005
1VQN	The structure of CC-HPMN AND CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(LOF))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ... Authors: Schmeing, T.M, Steitz, T.A. Deposit date: 2004-12-16 Release date: 2005-11-29 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.4 Å) Cite: An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA. Nature, 438, 2005
1VQ6	The structure of c-hpmn and CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui Descriptor: 23S ribosomal rna, 5'-R(*CP*(5AA)*(HFA))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ... Authors: Schmeing, T.M, Steitz, T.A. Deposit date: 2004-12-16 Release date: 2005-11-29 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.7 Å) Cite: An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA. Nature, 438, 2005
4WYK	Structure of the LRR and NTF2-like domains of NXF1 complexed with NXT1 Descriptor: NTF2-related export protein 1, Nuclear RNA export factor 1 Authors: Aibara, S, Valkov, E, Stewart, M. Deposit date: 2014-11-17 Release date: 2015-02-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.4 Å) Cite: The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA. Nucleic Acids Res., 43, 2015
8UAU	human ATE1 in complex with Arg-tRNA and a peptide substrate Descriptor: Isoform ATE1-2 of Arginyl-tRNA--protein transferase 1, RNA (76-MER), ZINC ION, ... Authors: Huang, W, Zhang, Y, Taylor, D.J. Deposit date: 2023-09-22 Release date: 2024-08-14 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (5.7 Å) Cite: Oligomerization and a distinct tRNA-binding loop are important regulators of human arginyl-transferase function. Nat Commun, 15, 2024
7NK1	1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201 Descriptor: Nanobody8201, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... Authors: Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. Deposit date: 2021-02-17 Release date: 2021-12-01 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (4.22 Å) Cite: Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
5DTO	Dengue virus full length NS5 complexed with viral Cap 0-RNA and SAH Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, ACETATE ION, MAGNESIUM ION, ... Authors: Zhao, Y, Soh, T.S, Lim, S.P, Chung, K.Y, Swaminathan, K, Vasudevan, S.G, Shi, P.-Y, Lescar, J, Luo, D. Deposit date: 2015-09-18 Release date: 2015-11-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.603 Å) Cite: Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5) Proc.Natl.Acad.Sci.USA, 112, 2015
5M52	Crystal structure of yeast Brr2 full-lenght in complex with Prp8 Jab1 domain Descriptor: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2 Authors: Wollenhaupt, J, Absmeier, E, Becke, C, Santos, K.F, Wahl, M.C. Deposit date: 2016-10-20 Release date: 2016-12-07 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2. Cell Cycle, 16, 2017
7NYB	TrmB complex with SAM Descriptor: S-ADENOSYLMETHIONINE, tRNA (guanine-N(7)-)-methyltransferase Authors: Blersch, K.F, Ficner, R, Neumann, P. Deposit date: 2021-03-22 Release date: 2021-09-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA. Rna Biol., 18, 2021

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