5GXH
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![BU of 5gxh by Molmil](/molmil-images/mine/5gxh) | The structure of the Gemin5 WD40 domain with AAUUUUUG | Descriptor: | GLYCEROL, Gem-associated protein 5, RNA (5'-R(*A*AP*UP*UP*UP*UP*UP*G)-3'), ... | Authors: | Xu, C, He, H, Li, Y, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2016-09-17 | Release date: | 2016-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly Genes Dev., 30, 2016
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5GXI
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![BU of 5gxi by Molmil](/molmil-images/mine/5gxi) | Structure of the Gemin5 WD40 domain in complex with AAUUUUUGAG | Descriptor: | Gem-associated protein 5, RNA (5'-R(*A*AP*UP*UP*UP*UP*UP*GP*AP*G)-3'), UNKNOWN ATOM OR ION | Authors: | Xu, C, He, H, Li, Y, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2016-09-18 | Release date: | 2016-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly Genes Dev., 30, 2016
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5NFV
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![BU of 5nfv by Molmil](/molmil-images/mine/5nfv) | Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CRISPR-associated endonuclease Cpf1, DNA non-target strand, ... | Authors: | Swarts, D.C, van der Oost, J, Jinek, M. | Deposit date: | 2017-03-16 | Release date: | 2017-06-14 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a. Mol. Cell, 66, 2017
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7Y9Y
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![BU of 7y9y by Molmil](/molmil-images/mine/7y9y) | Structure of the Cas7-11-Csx29-guide RNA-target RNA (no PFS) complex | Descriptor: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, RNA (27-MER), ... | Authors: | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | Deposit date: | 2022-06-26 | Release date: | 2022-11-09 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
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5WS2
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![BU of 5ws2 by Molmil](/molmil-images/mine/5ws2) | Crystal structure of mpy-RNase J (mutant S247A), an archaeal RNase J from Methanolobus psychrophilus R15, complex with RNA | Descriptor: | RNA (5'-R(P*AP*AP*AP*AP*A)-3'), Ribonuclease J, SULFATE ION, ... | Authors: | Li, D.F, Feng, N. | Deposit date: | 2016-12-05 | Release date: | 2017-12-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.398 Å) | Cite: | New molecular insights into an archaeal RNase J reveal a conserved processive exoribonucleolysis mechanism of the RNase J family Mol. Microbiol., 106, 2017
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7BKQ
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![BU of 7bkq by Molmil](/molmil-images/mine/7bkq) | CryoEM structure of MDA5-dsRNA filament in complex with ADP with 92-degree helical twist | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Isoform 2 of Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ... | Authors: | Yu, Q, Modis, Y. | Deposit date: | 2021-01-17 | Release date: | 2021-11-17 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA. Nat Commun, 12, 2021
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4WLW
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![BU of 4wlw by Molmil](/molmil-images/mine/4wlw) | CRYSTAL STRUCTURE OF THE AG(I) (ACTIVATOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA | Descriptor: | DNA NON-TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP *DTP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DGP*DCP*DTP*DGP*DGP*DAP *DAP*DGP*DGP*DTP*DC)-3, DNA TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP*DTP *DTP*DCP*DCP*DAP*DGP*DCP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DAP *DGP*DGP*DTP*DC)-3, HTH-type transcriptional regulator CueR, ... | Authors: | Philips, S.J, Canalizo-Hernandez, M, Mondragon, A, O'Halloran, T.V. | Deposit date: | 2014-10-08 | Release date: | 2015-09-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter. Science, 349, 2015
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7Y85
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![BU of 7y85 by Molmil](/molmil-images/mine/7y85) | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to self RNA target | Descriptor: | CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-06-22 | Release date: | 2022-12-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7Y81
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![BU of 7y81 by Molmil](/molmil-images/mine/7y81) | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to non-self RNA target | Descriptor: | MAGNESIUM ION, Non-self RNA target, RAMP superfamily protein, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-06-22 | Release date: | 2022-12-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7Y82
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![BU of 7y82 by Molmil](/molmil-images/mine/7y82) | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to self RNA target | Descriptor: | MAGNESIUM ION, RAMP superfamily protein, Self RNA target, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-06-22 | Release date: | 2022-12-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7Y83
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![BU of 7y83 by Molmil](/molmil-images/mine/7y83) | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to non-self RNA target | Descriptor: | CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-06-22 | Release date: | 2022-12-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7Y9X
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![BU of 7y9x by Molmil](/molmil-images/mine/7y9x) | Structure of the Cas7-11-Csx29-guide RNA complex | Descriptor: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, ZINC ION, ... | Authors: | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | Deposit date: | 2022-06-26 | Release date: | 2022-11-09 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.49 Å) | Cite: | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
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1EXD
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![BU of 1exd by Molmil](/molmil-images/mine/1exd) | CRYSTAL STRUCTURE OF A TIGHT-BINDING GLUTAMINE TRNA BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE | Descriptor: | ADENOSINE MONOPHOSPHATE, GLUTAMINE TRNA APTAMER, GLUTAMINYL-TRNA SYNTHETASE, ... | Authors: | Bullock, T.L, Sherlin, L.D, Perona, J.J. | Deposit date: | 2000-05-02 | Release date: | 2000-05-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Tertiary core rearrangements in a tight binding transfer RNA aptamer. Nat.Struct.Biol., 7, 2000
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6N5T
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![BU of 6n5t by Molmil](/molmil-images/mine/6n5t) | Structure of Human pir-miRNA-378a Apical Loop Fused to the YdaO Riboswitch Scaffold | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Shoffner, G.M, Peng, Z, Guo, F. | Deposit date: | 2018-11-22 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.787 Å) | Cite: | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography To Be Published
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6N5K
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![BU of 6n5k by Molmil](/molmil-images/mine/6n5k) | Structure of Human pir-miRNA-449c Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Shoffner, G.M, Peng, Z, Guo, F. | Deposit date: | 2018-11-22 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.098 Å) | Cite: | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography To Be Published
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6N5O
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![BU of 6n5o by Molmil](/molmil-images/mine/6n5o) | Structure of Human pir-miRNA-202 Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Shoffner, G.M, Peng, Z, Guo, F. | Deposit date: | 2018-11-22 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.708 Å) | Cite: | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography To Be Published
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6N5N
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![BU of 6n5n by Molmil](/molmil-images/mine/6n5n) | Structure of Human pir-miRNA-208a Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Shoffner, G.M, Peng, Z, Guo, F. | Deposit date: | 2018-11-22 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.951 Å) | Cite: | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography To Be Published
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6N5S
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![BU of 6n5s by Molmil](/molmil-images/mine/6n5s) | Structure of Human pir-miRNA-320b-2 Apical Loop and One-base-pair Stem Fused to the YdaO Riboswitch Scaffold | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | Authors: | Shoffner, G.M, Peng, Z, Guo, F. | Deposit date: | 2018-11-22 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography To Be Published
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6N5Q
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![BU of 6n5q by Molmil](/molmil-images/mine/6n5q) | Structure of Human pir-miRNA-378a Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Shoffner, G.M, Peng, Z, Guo, F. | Deposit date: | 2018-11-22 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.946 Å) | Cite: | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography To Be Published
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6GPG
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![BU of 6gpg by Molmil](/molmil-images/mine/6gpg) | Structure of the RIG-I Singleton-Merten syndrome variant C268F | Descriptor: | MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*CP*G)-3'), ... | Authors: | Laessig, C, Lammens, K, Hopfner, K.-P. | Deposit date: | 2018-06-05 | Release date: | 2018-08-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.894 Å) | Cite: | Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants. Elife, 7, 2018
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7NIC
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![BU of 7nic by Molmil](/molmil-images/mine/7nic) | |
7NGA
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![BU of 7nga by Molmil](/molmil-images/mine/7nga) | |
7NIQ
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![BU of 7niq by Molmil](/molmil-images/mine/7niq) | |
7Y80
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![BU of 7y80 by Molmil](/molmil-images/mine/7y80) | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA binary complex | Descriptor: | MAGNESIUM ION, RAMP superfamily protein, ZINC ION, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-06-22 | Release date: | 2022-12-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7Y84
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![BU of 7y84 by Molmil](/molmil-images/mine/7y84) | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease | Descriptor: | CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-06-22 | Release date: | 2022-12-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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