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6ZMP
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BU of 6zmp by Molmil
Crystal structure of Chaetomium thermophilum Naa20 in complex with a bisubstrate analogue
Descriptor: CARBOXYMETHYL COENZYME *A, CMC-MET-ASP-GLU-LEU, N-terminal acetyltransferase-like protein
Authors:Layer, D, Kopp, J, Sinning, I.
Deposit date:2020-07-03
Release date:2020-12-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural basis of Naa20 activity towards a canonical NatB substrate.
Commun Biol, 4, 2021
5W4O
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BU of 5w4o by Molmil
Structure of the R18A mutant of the HIV-1 capsid protein
Descriptor: CHLORIDE ION, Capsid protein p24, IODIDE ION
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-06-12
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket.
MBio, 10, 2019
6ZZ6
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BU of 6zz6 by Molmil
Cryo-EM structure of S.cerevisiae cohesin-Scc2-DNA complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (34-MER), MAGNESIUM ION, ...
Authors:Lee, B.-G, Gonzalez Llamazares, A, Collier, J, Nasmyth, K.A, Lowe, J.
Deposit date:2020-08-04
Release date:2020-09-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3.
Elife, 9, 2020
7A0V
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BU of 7a0v by Molmil
Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody
Descriptor: GLYCEROL, MAGNESIUM ION, Nanobody 13015, ...
Authors:Paesmans, J, Galicia, C, Martin, E, Versees, W.
Deposit date:2020-08-11
Release date:2020-12-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations.
Elife, 9, 2020
7A65
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BU of 7a65 by Molmil
Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6E
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BU of 7a6e by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A7A
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BU of 7a7a by Molmil
Cryo-EM structure of W107R after heme uptake (2heme molecules) KatG from M. tuberculosis
Descriptor: Catalase-peroxidase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Blundell, T.L, Chaplin, A.K, Munir, A.
Deposit date:2020-08-27
Release date:2021-01-27
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Using cryo-EM to understand antimycobacterial resistance in the catalase-peroxidase (KatG) from Mycobacterium tuberculosis.
Structure, 29, 2021
7ABA
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BU of 7aba by Molmil
The structure of the Bottromycin biosynthetic protein SalCYP
Descriptor: HEME C, SalCYP
Authors:Adam, S, Koehnke, J.
Deposit date:2020-09-07
Release date:2020-12-02
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.85002315 Å)
Cite:Characterization of the Stereoselective P450 Enzyme BotCYP Enables the In Vitro Biosynthesis of the Bottromycin Core Scaffold.
J.Am.Chem.Soc., 142, 2020
7AD9
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BU of 7ad9 by Molmil
Structure of the Lifeact-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Belyy, A, Merino, F, Sitsel, O, Raunser, S.
Deposit date:2020-09-14
Release date:2020-10-28
Last modified:2025-04-09
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Lifeact-F-actin complex.
Plos Biol., 18, 2020
5W7B
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BU of 5w7b by Molmil
Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorelik, A, Illes, K, Nagar, B.
Deposit date:2017-06-19
Release date:2018-01-03
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6ZSE
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BU of 6zse by Molmil
Human mitochondrial ribosome in complex with mRNA, A/P-tRNA and P/E-tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-09-16
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
6ZQD
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BU of 6zqd by Molmil
Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
Authors:Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R.
Deposit date:2020-07-09
Release date:2020-09-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:90 S pre-ribosome transformation into the primordial 40 S subunit.
Science, 369, 2020
6ZU5
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BU of 6zu5 by Molmil
Structure of the Paranosema locustae ribosome in complex with Lso2
Descriptor: 18S rRNA, 25S rRNA, 5S rRNA, ...
Authors:Ehrenbolger, K, Jespersen, N, Sharma, H, Sokolova, Y.Y, Tokarev, Y.S, Vossbrinck, C.R, Barandun, J.
Deposit date:2020-07-21
Release date:2020-11-04
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome.
Plos Biol., 18, 2020
6ZXX
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BU of 6zxx by Molmil
Catabolic reductive dehalogenase NpRdhA, N-terminally tagged.
Descriptor: 3 bromo 4 hydroxybenzoic acid, 3,5-bis(bromanyl)-4-oxidanyl-benzoic acid, BROMIDE ION, ...
Authors:Leys, D, Halliwell, T.
Deposit date:2020-07-30
Release date:2020-09-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope.
Microorganisms, 8, 2020
6ZYD
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BU of 6zyd by Molmil
YnaI
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Low conductance mechanosensitive channel YnaI,Low conductance mechanosensitive channel YnaI
Authors:Flegler, V.J, Rasmussen, A, Rao, S, Wu, N, Zenobi, R, Sansom, M.S.P, Hedrich, R, Rasmussen, T, Boettcher, B.
Deposit date:2020-07-31
Release date:2020-11-25
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The MscS-like channel YnaI has a gating mechanism based on flexible pore helices.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZYM
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BU of 6zym by Molmil
Human C Complex Spliceosome - High-resolution CORE
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Corepressor interacting with RBPJ 1, ...
Authors:Bertram, K, Kastner, B.
Deposit date:2020-08-02
Release date:2020-10-14
Last modified:2025-10-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Mol.Cell, 80, 2020
7A24
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BU of 7a24 by Molmil
Assembly intermediate of the plant mitochondrial complex I
Descriptor: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 13kDa, 15kDa, ...
Authors:Soufari, H, Waltz, F, Hashem, Y.
Deposit date:2020-08-16
Release date:2020-10-28
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM.
Nat Commun, 11, 2020
3J6Y
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BU of 3j6y by Molmil
S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I)
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
Authors:Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A.
Deposit date:2014-04-16
Release date:2014-06-11
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
7A69
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BU of 7a69 by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and vincristine
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-21
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6F
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BU of 7a6f by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A76
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BU of 7a76 by Molmil
Bacillithiol Disulfide Reductase Bdr (YpdA) from Bacillus cereus
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SODIUM ION, THIOREDOXIN REDUCTASE
Authors:Hammerstad, M, Gudim, I, Hersleth, H.-P.
Deposit date:2020-08-27
Release date:2020-12-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Crystal Structures of Bacillithiol Disulfide Reductase Bdr (YpdA) Provide Structural and Functional Insight into a New Type of FAD-Containing NADPH-Dependent Oxidoreductase.
Biochemistry, 59, 2020
7A5I
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BU of 7a5i by Molmil
Structure of the human mitoribosome with A- P-and E-site mt-tRNAs
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ...
Authors:Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V.
Deposit date:2020-08-21
Release date:2020-12-23
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020
7ADD
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BU of 7add by Molmil
Transcription termination intermediate complex IIIa
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
Authors:Said, N, Hilal, T, Loll, B, Wahl, C.M.
Deposit date:2020-09-14
Release date:2020-11-25
Last modified:2025-10-01
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
5W90
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BU of 5w90 by Molmil
FEZ-1 metallo-beta-lactamase from Legionella gormanii modelled with unknown ligand
Descriptor: FEZ-1 protein, GLYCEROL, SULFATE ION, ...
Authors:Garcia-Saez, I, Mercuri, P.S, Kahn, R, Shabalin, I.G, Raczynska, J.E, Jaskolski, M, Minor, W, Papamicael, C, Frere, J.M, Galleni, M, Dideberg, O.
Deposit date:2017-06-22
Release date:2018-06-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril.
J. Mol. Biol., 325, 2003
6ZNM
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BU of 6znm by Molmil
The pointed end complex of dynactin bound to BICDR1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ...
Authors:Lau, C.K, Lacey, S.E, Carter, A.P.
Deposit date:2020-07-06
Release date:2020-07-29
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM reveals the complex architecture of dynactin's shoulder region and pointed end.
Embo J., 40, 2021

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