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5LBF
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BU of 5lbf by Molmil
HIF prolyl hydroxylase 2 (PHD2/EGLN1) K293K/G294E variant in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/FG2216)
Descriptor: BICARBONATE ION, Egl nine homolog 1, MANGANESE (II) ION, ...
Authors:Chowdhury, R, Schofield, C.J.
Deposit date:2016-06-16
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8995 Å)
Cite:Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Nat Commun, 7, 2016
5L6L
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BU of 5l6l by Molmil
Structure of Caulobacter crescentus VapBC1 bound to operator DNA
Descriptor: DNA (27-MER), Ribonuclease VapC, VapB family protein
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
2MFF
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BU of 2mff by Molmil
Csr/Rsm protein-RNA recognition - A molecular affinity ruler: RsmZ(SL3)/RsmE(dimer) 2:1 complex
Descriptor: Carbon storage regulator homolog, SL3(RsmZ) RNA
Authors:Duss, O, Diarra Dit Konte, N, Michel, E, Schubert, M, Allain, F.H.-T.
Deposit date:2013-10-11
Release date:2014-02-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition.
Nucleic Acids Res., 42, 2014
6QV7
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BU of 6qv7 by Molmil
Crystal structure of a CHAD domain from Chlorobium tepidum
Descriptor: 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, SULFATE ION, ...
Authors:Lorenzo-Orts, L, Hothorn, M.
Deposit date:2019-03-01
Release date:2019-05-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Molecular characterization of CHAD domains as inorganic polyphosphate-binding modules.
Life Sci Alliance, 2, 2019
6QWV
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BU of 6qwv by Molmil
SARM1 SAM1-2 domains
Descriptor: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Sporny, M, Isupov, N.M, Opatowsky, Y.
Deposit date:2019-03-06
Release date:2019-07-03
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural Evidence for an Octameric Ring Arrangement of SARM1.
J.Mol.Biol., 431, 2019
5LAT
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BU of 5lat by Molmil
HIF prolyl hydroxylase 2 (PHD2/EGLN1) P317R variant in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9)
Descriptor: BICARBONATE ION, Egl nine homolog 1, GLYCEROL, ...
Authors:Chowdhury, R, Schofield, C.J.
Deposit date:2016-06-15
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Nat Commun, 7, 2016
6QXA
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BU of 6qxa by Molmil
Structure of membrane bound pyrophosphatase from Thermotoga maritima in complex with imidodiphosphate and N-[(2-amino-6-benzothiazolyl)methyl]-1H-indole-2-carboxamide (ATC)
Descriptor: (4S,5S)-1,2-DITHIANE-4,5-DIOL, IMIDODIPHOSPHORIC ACID, K(+)-stimulated pyrophosphate-energized sodium pump, ...
Authors:Vidilaseris, K, Goldman, A.
Deposit date:2019-03-07
Release date:2019-04-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Asymmetry in catalysis byThermotoga maritimamembrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor.
Sci Adv, 5, 2019
5L9B
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BU of 5l9b by Molmil
HIF PROLYL HYDROXYLASE 2 (PHD2/ EGLN1) IN COMPLEX WITH 2-OXOGLUTARATE (2OG) AND HIF-1ALPHA CODD (556-574)
Descriptor: 2-OXOGLUTARIC ACID, Egl nine homolog 1, Hypoxia-inducible factor 1-alpha, ...
Authors:Chowdhury, R, Schofield, C.J.
Deposit date:2016-06-10
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Nat Commun, 7, 2016
2MFH
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BU of 2mfh by Molmil
Csr/Rsm protein-RNA recognition - A molecular affinity ruler: RsmZ(36-44)/RsmE(dimer) 2:1 complex
Descriptor: Carbon storage regulator homolog, RsmZ(36-44) RNA
Authors:Duss, O, Diarra Dit Konte, N, Michel, E, Schubert, M, Allain, F.H.-T.
Deposit date:2013-10-11
Release date:2014-02-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition.
Nucleic Acids Res., 42, 2014
6QS6
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BU of 6qs6 by Molmil
ClpB (DWB and K476C mutant) bound to casein in presence of ATPgammaS - state KC-1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Deville, C, Saibil, H.R.
Deposit date:2019-02-20
Release date:2019-07-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Cell Rep, 27, 2019
5LA9
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BU of 5la9 by Molmil
HIF prolyl hydroxylase 2 (PHD2-R281C/V314C) cross-linked to HIF-1alpha NODD-L397C/D412C and N-oxalylglycine (NOG) (complex-2)
Descriptor: Egl nine homolog 1, Hypoxia-inducible factor 1-alpha, MANGANESE (II) ION, ...
Authors:Chowdhury, R, Schofield, C.J.
Deposit date:2016-06-14
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.813 Å)
Cite:Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Nat Commun, 7, 2016
6RG5
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BU of 6rg5 by Molmil
Human Carbonic Anhydrase II in complex with 4-(2-hydroxyethyl)benzenesulfonamide
Descriptor: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-(2-hydroxyethyl)benzenesulfonamide, Carbonic anhydrase 2, ...
Authors:Gloeckner, S, Heine, A, Klebe, G.
Deposit date:2019-04-16
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.089 Å)
Cite:Human Carbonic Anhydrase II in complex with 4-(2-hydroxyethyl)benzenesulfonamide
To Be Published
6QP9
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BU of 6qp9 by Molmil
Drosophila Semaphorin 1a, extracellular domains 1-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin-1A
Authors:Rozbesky, D, Robinson, R.A, Harlos, K, Siebold, C, Jones, E.Y.
Deposit date:2019-02-13
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning.
Nat Commun, 10, 2019
6QPI
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BU of 6qpi by Molmil
Cryo-EM structure of calcium-free mTMEM16F lipid scramblase in nanodisc
Descriptor: Anoctamin-6
Authors:Alvadia, C, Lim, N.K, Clerico Mosina, V, Oostergetel, G.T, Dutzler, R, Paulino, C.
Deposit date:2019-02-14
Release date:2019-03-06
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F.
Elife, 8, 2019
6RIG
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BU of 6rig by Molmil
Human Carbonic Anhydrase II in complex with 4-Hydroxybenzenesulfonamide
Descriptor: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-oxidanylbenzenesulfonamide, Carbonic anhydrase 2, ...
Authors:Gloeckner, S, Heine, A, Klebe, G.
Deposit date:2019-04-24
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (0.999 Å)
Cite:Human Carbonic Anhydrase II in complex with 4-Hydroxybenzenesulfonamide
To Be Published
2M5E
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BU of 2m5e by Molmil
Structure of the C-domain of Calcium-saturated Calmodulin bound to the IQ motif of NaV1.2
Descriptor: CALCIUM ION, Calmodulin, Sodium channel protein type 2 subunit alpha
Authors:Fowler, C.A, Feldkamp, M.D, Yu, L, Shea, M.A.
Deposit date:2013-02-21
Release date:2014-07-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1.2.
Biophys. Chem., 224, 2017
5L6M
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BU of 5l6m by Molmil
Structure of Caulobacter crescentus VapBC1 (VapB1deltaC:VapC1 form)
Descriptor: GLYCEROL, MALONATE ION, Ribonuclease VapC, ...
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
6QVM
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BU of 6qvm by Molmil
Undecaheme cytochrome from S-layer of Carboxydothermus ferrireducens
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ...
Authors:Osipov, E.M, Dergousova, N.I, Boyko, K.M, Tikhonova, T.V, Gavrilov, S.F, Popov, V.O.
Deposit date:2019-03-04
Release date:2020-03-25
Last modified:2023-02-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Extracellular Fe(III) reductase structure reveals a modular organization enabling S-layer insertion and electron transfer to insoluble substrates
Structure, 2023
5L6V
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BU of 5l6v by Molmil
Crystal structure of E. coli ADP-glucose pyrophosphorylase (AGPase) in complex with a negative allosteric regulator adenosine monophosphate (AMP) - AGPase*AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Glucose-1-phosphate adenylyltransferase, PHOSPHATE ION, ...
Authors:Cifuente, J.O, Albesa-Jove, D, Comino, N, Madariaga-Marcos, J, Agirre, J, Lopez-Fernandez, S, Garcia-Alija, M, Guerin, M.E.
Deposit date:2016-05-31
Release date:2016-09-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.667 Å)
Cite:Structural Basis of Glycogen Biosynthesis Regulation in Bacteria.
Structure, 24, 2016
6QW4
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BU of 6qw4 by Molmil
Engineered streptavidin variant (ACGR) in complex with the Strep-tag II peptide
Descriptor: Strep-tag II peptide, Streptavidin
Authors:Skerra, A, Eichinger, A.
Deposit date:2019-03-05
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide.
J.Mol.Biol., 433, 2021
2MJ9
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BU of 2mj9 by Molmil
Designed Exendin-4 analogues
Descriptor: Exendin-4
Authors:Rovo, P, Farkas, V, Straner, P, Szabo, M, Jermendy, A, Hegyi, O, Toth, G.K, Perczel, A.
Deposit date:2013-12-30
Release date:2014-06-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Rational design of alpha-helix-stabilized exendin-4 analogues.
Biochemistry, 53, 2014
6S2F
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BU of 6s2f by Molmil
Cryo-EM structure of Ctf18-1-8 in complex with the catalytic domain of DNA polymerase epsilon (Class 2)
Descriptor: Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, DNA polymerase epsilon catalytic subunit A, ...
Authors:Grabarczyk, D.B, Song, B.
Deposit date:2019-06-20
Release date:2020-07-08
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication.
Nucleic Acids Res., 48, 2020
6QUA
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BU of 6qua by Molmil
The complex structure of hsRosR-SG (vng0258/RosR-SG)
Descriptor: DNA (28-MER), MANGANESE (II) ION, SULFATE ION, ...
Authors:Shaanan, B, Kutnowski, N.
Deposit date:2019-02-27
Release date:2019-07-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.681 Å)
Cite:Specificity of protein-DNA interactions in hypersaline environment: structural studies on complexes of Halobacterium salinarum oxidative stress-dependent protein hsRosR.
Nucleic Acids Res., 47, 2019
2MJN
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BU of 2mjn by Molmil
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
Descriptor: Nucleolysin TIA-1 isoform p40
Authors:Sattler, M, Wang, I.
Deposit date:2014-01-13
Release date:2014-04-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
Nucleic Acids Res., 42, 2014
6QXT
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BU of 6qxt by Molmil
Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system
Descriptor: CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ...
Authors:Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B.
Deposit date:2019-03-08
Release date:2019-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019

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PDB entries from 2024-08-14

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