PDB: 8880 resultsInfo pagesStatus searchChemie searchBIRD

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6EUX	Structure of the midlink and cap-binding domains of influenza B polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor Descriptor: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, Polymerase basic protein 2 Authors: Cusack, S, Gaudon, S. Deposit date: 2017-10-31 Release date: 2017-12-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018
2P3L	Crystal Structure of Dengue Methyltransferase in Complex with GpppA and S-Adenosyl-L-Homocysteine Descriptor: CITRIC ACID, GLYCEROL, GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ... Authors: Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP) Deposit date: 2007-03-09 Release date: 2007-08-28 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5 J.Mol.Biol., 372, 2007
2P3O	Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppA and S-Adenosyl-L-homocysteine Descriptor: CITRIC ACID, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, ... Authors: Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP) Deposit date: 2007-03-09 Release date: 2007-08-28 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.756 Å) Cite: Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5 J.Mol.Biol., 372, 2007
2P41	Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppG2'OMe and S-Adenosyl-L-homocysteine Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-GUANOSINE, CITRIC ACID, GLYCEROL, ... Authors: Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP) Deposit date: 2007-03-11 Release date: 2007-08-28 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.801 Å) Cite: Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5 J.Mol.Biol., 372, 2007
2K7L	NMR structure of a complex formed by the C-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 Descriptor: General transcription factor IIF subunit 1, centFCP1-T584PO4 peptide Authors: Yang, A, Abbott, K.L, Desjardins, A, Di Lello, P, Omichinski, J.G, Legault, P. Deposit date: 2008-08-13 Release date: 2009-06-02 Last modified: 2020-02-19 Method: SOLUTION NMR Cite: NMR structure of a complex formed by the carboxyl-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 phosphatase Biochemistry, 48, 2009
2P3Q	Crystal Structure of Dengue Methyltransferase in Complex with GpppG and S-Adenosyl-L-homocysteine Descriptor: DIGUANOSINE-5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... Authors: Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP) Deposit date: 2007-03-09 Release date: 2007-08-28 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5 J.Mol.Biol., 372, 2007
3SPZ	DNA Polymerase(L415A/L561A/S565G/Y567A) Ternary Complex with dUpCpp Opposite dA (Ca2+) Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]uridine, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3', 5'-D(P*GP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ... Authors: Xia, S, Konigsberg, W.H, Wang, J. Deposit date: 2011-07-04 Release date: 2011-10-12 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase. Biochemistry, 50, 2011
6E3N	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-4-oxo-6-(o-tolyl)-1,4-dihydropyridine-2-carboxylic acid Descriptor: 3-hydroxy-6-(2-methylphenyl)-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein Authors: Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. Deposit date: 2018-07-14 Release date: 2019-07-17 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.19 Å) Cite: SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
4FJL	RB69 DNA polymerase ternary complex with dGTP/dA Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.87 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJG	RB69 DNA polymerase ternary complex with dATP/dC Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.02 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FK0	RB69 DNA polymerase ternary complex with dCTP/dG Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-12 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.18 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJJ	RB69 DNA polymerase ternary complex with dTTP/dC Descriptor: CALCIUM ION, DNA polymerase, DNA primer, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.99 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJH	RB69 DNA polymerase ternary complex with dGTP/dC Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.11 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJ5	RB69 DNA polymerase ternary complex with dATP/dT Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.05 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJK	RB69 DNA polymerase ternary complex with dATP/dA Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJM	RB69 DNA polymerase ternary complex with dCTP/dA Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.02 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJN	RB69 DNA polymerase ternary complex with dTTP/dA Descriptor: CALCIUM ION, DNA polymerase, DNA primer, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.98 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
6E3O	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid Descriptor: 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein Authors: Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. Deposit date: 2018-07-14 Release date: 2019-07-17 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.19 Å) Cite: SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
6E3P	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(3-(1H-tetrazol-5-yl)phenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid Descriptor: 3-hydroxy-4-oxo-6-[3-(1H-tetrazol-5-yl)phenyl]-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein Authors: Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. Deposit date: 2018-07-14 Release date: 2019-07-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.8 Å) Cite: SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
3UIQ	RB69 DNA Polymerase Ternary Complex containing dUpNpp Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3', 5'-D(*TP*CP*GP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ... Authors: Xia, S, Konigsberg, W.H, Wang, J. Deposit date: 2011-11-05 Release date: 2012-04-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.879 Å) Cite: Bidentate and tridentate metal-ion coordination states within ternary complexes of RB69 DNA polymerase. Protein Sci., 21, 2012
4FJI	RB69 DNA polymerase ternary complex with dcTP/dC Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJ9	RB69 DNA polymerase ternary complex with dTTP/dT Descriptor: CALCIUM ION, DNA polymerase, DNA primer, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.97 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJX	RB69 DNA polymerase ternary complex with dATP/dG Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-12 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.11 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FJ7	RB69 DNA polymerase ternary complex with dGTP/dT Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-11 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
4FK4	RB69 DNA polymerase ternary complex with dGTP/dG Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-06-12 Release date: 2012-12-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013

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