6ALI
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3O6T
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7WGE
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![BU of 7wge by Molmil](/molmil-images/mine/7wge) | Human NLRP1 complexed with thioredoxin | Descriptor: | MAGNESIUM ION, NACHT, LRR and PYD domains-containing protein 1, ... | Authors: | Zhang, Z, Ohto, U, Shimizu, T. | Deposit date: | 2021-12-28 | Release date: | 2023-07-05 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for thioredoxin-mediated suppression of NLRP1 inflammasome. Nature, 622, 2023
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5DQY
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![BU of 5dqy by Molmil](/molmil-images/mine/5dqy) | A fully oxidized human thioredoxin | Descriptor: | BENZOIC ACID, CHLORIDE ION, GLYCEROL, ... | Authors: | Hwang, J. | Deposit date: | 2015-09-15 | Release date: | 2015-12-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of fully oxidized human thioredoxin. Biochem.Biophys.Res.Commun., 467, 2015
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5NYL
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1TXX
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7XAO
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![BU of 7xao by Molmil](/molmil-images/mine/7xao) | Crystal structure of thioredoxin 1 | Descriptor: | Thioredoxin | Authors: | Chang, Y.J, Park, H.H. | Deposit date: | 2022-03-18 | Release date: | 2022-06-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High-resolution crystal structure of Acinetobacter baumannii thioredoxin 1. Biochem.Biophys.Res.Commun., 608, 2022
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7P0X
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![BU of 7p0x by Molmil](/molmil-images/mine/7p0x) | Crystal structure of Thioredoxin reductase from Brugia Malayi | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Fata, F, Ardini, M, Silvestri, I, Gabriele, F, Cheng, Q, Arner, E.S.J, Williams, D.L. | Deposit date: | 2021-06-30 | Release date: | 2022-04-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus. Redox Biol, 51, 2022
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7PVJ
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![BU of 7pvj by Molmil](/molmil-images/mine/7pvj) | Crystal structure of Thioredoxin Reductase from Brugia Malayi in complex with auranofin | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Fata, F, Ardini, M, Silvestri, I, Gabriele, F, Ippoliti, R, Gencheva, R, Cheng, Q, Arner, E.S.J, Angelucci, F, Williams, D.L. | Deposit date: | 2021-10-04 | Release date: | 2022-04-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus. Redox Biol, 51, 2022
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7PUT
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![BU of 7put by Molmil](/molmil-images/mine/7put) | Crystal structure of Thioredoxin Reductase from Brugia Malayi in complex with NADP(H) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Fata, F, Ardini, M, Silvestri, I, Gabriele, F, Ippoliti, R, Gencheva, R, Cheng, Q, Arner, E.S.J, Angelucci, F, Williams, D.L. | Deposit date: | 2021-09-30 | Release date: | 2022-04-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus. Redox Biol, 51, 2022
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1XWC
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![BU of 1xwc by Molmil](/molmil-images/mine/1xwc) | Drosophila thioredoxin, reduced, P6522 | Descriptor: | thioredoxin | Authors: | Wahl, M.C, Irmler, A, Hecker, B, Schirmer, R.H, Becker, K. | Deposit date: | 2004-10-29 | Release date: | 2004-11-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster J.Mol.Biol., 345, 2005
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1XWB
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![BU of 1xwb by Molmil](/molmil-images/mine/1xwb) | Drospohila thioredoxin, oxidized, P42212 | Descriptor: | CADMIUM ION, thioredoxin | Authors: | Wahl, M.C, Irmler, A, Hecker, B, Schirmer, R.H, Becker, K. | Deposit date: | 2004-10-29 | Release date: | 2004-11-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster J.Mol.Biol., 345, 2005
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1XWA
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![BU of 1xwa by Molmil](/molmil-images/mine/1xwa) | Drospohila thioredoxin, oxidized, P41212 | Descriptor: | CADMIUM ION, CHLORIDE ION, thioredoxin | Authors: | Wahl, M.C, Irmler, A, Hecker, B, Schirmer, R.H, Becker, K. | Deposit date: | 2004-10-29 | Release date: | 2004-11-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster J.Mol.Biol., 345, 2005
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1H6V
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![BU of 1h6v by Molmil](/molmil-images/mine/1h6v) | Mammalian thioredoxin reductase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, THIOREDOXIN REDUCTASE | Authors: | Sandalova, T, Zhong, L, Lindqvist, Y, Holmgren, A, Schneider, G. | Deposit date: | 2001-06-27 | Release date: | 2001-08-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Three-Dimensional Structure of a Mammalian Thioredoxin Reductase: Implication for Mechanism and Evolution of a Selenocysteine Dependent Enzyme Proc.Natl.Acad.Sci.USA, 98, 2001
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3PIL
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![BU of 3pil by Molmil](/molmil-images/mine/3pil) | Crystal structure of Mxr1 from Saccharomyces cerevisiae in reduced form | Descriptor: | ACETATE ION, Peptide methionine sulfoxide reductase | Authors: | Ma, X.X, Guo, P.C, Shi, W.W, Luo, M, Tan, X.F, Chen, Y, Zhou, C.Z. | Deposit date: | 2010-11-07 | Release date: | 2011-02-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural plasticity of the thioredoxin recognition site of yeast methionine S-sulfoxide reductase Mxr1 J.Biol.Chem., 286, 2011
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2Q7V
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![BU of 2q7v by Molmil](/molmil-images/mine/2q7v) | Crystal Structure of Deinococcus Radiodurans Thioredoxin Reductase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase | Authors: | Sanders, D.A.R, Obiero, J, Bonderoff, S.A, Goertzen, M.M. | Deposit date: | 2007-06-07 | Release date: | 2008-07-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Thioredoxin system from Deinococcus radiodurans. J.Bacteriol., 192, 2010
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3KH7
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![BU of 3kh7 by Molmil](/molmil-images/mine/3kh7) | Crystal structure of the periplasmic soluble domain of reduced CcmG from Pseudomonas aeruginosa | Descriptor: | Thiol:disulfide interchange protein dsbE | Authors: | Di Matteo, A, Calosci, N, Gianni, S, Jemth, P, Brunori, M, Travaglini Allocatelli, C. | Deposit date: | 2009-10-30 | Release date: | 2010-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus. Proteins, 78, 2010
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3KH9
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![BU of 3kh9 by Molmil](/molmil-images/mine/3kh9) | Crystal structure of the periplasmic soluble domain of oxidized CcmG from Pseudomonas aeruginosa | Descriptor: | Thiol:disulfide interchange protein dsbE | Authors: | Di Matteo, A, Calosci, N, Gianni, S, Jemth, P, Brunori, M, Travaglini Allocatelli, C. | Deposit date: | 2009-10-30 | Release date: | 2010-04-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus. Proteins, 78, 2010
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7SCE
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![BU of 7sce by Molmil](/molmil-images/mine/7sce) | Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-2 octasaccharide substrate and co-factor product PAP | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5 | Authors: | Wander, R, Kaminski, A.M, Krahn, J.M, Liu, J, Pedersen, L.C. | Deposit date: | 2021-09-27 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate Acs Catalysis, 11, 2021
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7SCD
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![BU of 7scd by Molmil](/molmil-images/mine/7scd) | Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-1 octasaccharide substrate and co-factor product PAP | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5 | Authors: | Wander, R, Kaminski, A.M, Krahn, J.M, Liu, J, Pedersen, L.C. | Deposit date: | 2021-09-27 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate Acs Catalysis, 11, 2021
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2IPA
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![BU of 2ipa by Molmil](/molmil-images/mine/2ipa) | solution structure of Trx-ArsC complex | Descriptor: | Protein arsC, Thioredoxin | Authors: | Jin, C, Hu, Y, Li, Y, Zhang, X. | Deposit date: | 2006-10-12 | Release date: | 2007-02-13 | Last modified: | 2021-11-10 | Method: | SOLUTION NMR | Cite: | Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis. J.Biol.Chem., 282, 2007
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2O85
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![BU of 2o85 by Molmil](/molmil-images/mine/2o85) | S. Aureus thioredoxin P31T mutant | Descriptor: | Thioredoxin | Authors: | Roos, G, Loris, R, Messens, J. | Deposit date: | 2006-12-12 | Release date: | 2007-07-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin J.Mol.Biol., 368, 2007
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2O7K
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![BU of 2o7k by Molmil](/molmil-images/mine/2o7k) | S. aureus thioredoxin | Descriptor: | Thioredoxin | Authors: | Roos, G, Garcia-Pino, A, Van Belle, K, Brosens, E, Wahni, K, Vandenbussche, G, Wyns, L, Loris, R, Messens, J. | Deposit date: | 2006-12-11 | Release date: | 2007-07-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin J.Mol.Biol., 368, 2007
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3DIE
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2O89
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![BU of 2o89 by Molmil](/molmil-images/mine/2o89) | S. aureus thioredoxin P31T/C32S mutant | Descriptor: | Thioredoxin | Authors: | Roos, G, Loris, R, Messens, J. | Deposit date: | 2006-12-12 | Release date: | 2007-07-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin J.Mol.Biol., 368, 2007
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