9C4G
 
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9C3U
 | | Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrate containing GTTTAC as recognition sequence | | Descriptor: | DNA1, DNA2, Methyltransferase, ... | | Authors: | Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K. | | Deposit date: | 2024-06-02 | | Release date: | 2024-09-11 | | Last modified: | 2024-09-25 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.
Nat Commun, 15, 2024
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9C3S
 | | Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrate containing GTATAC as recognition sequence | | Descriptor: | DNA1, DNA2, Methyltransferase, ... | | Authors: | Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K. | | Deposit date: | 2024-06-02 | | Release date: | 2024-09-11 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.
Nat Commun, 15, 2024
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9C3T
 | | Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrate containing GTAAAC as recognition sequence | | Descriptor: | DNA1, DNA2, Methyltransferase, ... | | Authors: | Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K. | | Deposit date: | 2024-06-02 | | Release date: | 2024-09-11 | | Last modified: | 2024-09-25 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.
Nat Commun, 15, 2024
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9FJN
 | | Solution NMR structure of a peptide encompassing residues 2-19 of the human formin INF2 | | Descriptor: | Inverted formin-2 | | Authors: | Jimenez, M.A, Comas, L, Labat-de-Hoz, L, Correas, I, Alonso, M.A. | | Deposit date: | 2024-05-31 | | Release date: | 2024-09-11 | | Method: | SOLUTION NMR | | Cite: | Structure and function of the N-terminal extension of the formin INF2.
Cell Mol Life Sci, 79, 2022
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9FJW
 | | Solution NMR structure of a peptide encompassing residues 2-36 of the human formin INF2 | | Descriptor: | Inverted formin-2 | | Authors: | Jimenez, M.A, Comas, L, Labat-de-Hoz, L, Correas, I, Alonso, M.A. | | Deposit date: | 2024-05-31 | | Release date: | 2024-09-11 | | Method: | SOLUTION NMR | | Cite: | Structure and function of the N-terminal extension of the formin INF2.
Cell Mol Life Sci, 79, 2022
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9C1U
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8ZNR
 | | Cryo-EM structure of Cas8-HNH system at ssDNA-bound state | | Descriptor: | DNA (35-MER), RNA (56-MER), protein structure | | Authors: | Zhang, H, Zhu, H, Li, X, Liu, Y. | | Deposit date: | 2024-05-28 | | Release date: | 2024-10-02 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis for the type I-F Cas8-HNH system.
Embo J., 2024
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9C0O
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9FH9
 | | Structure of CyclinB1 N-terminus bound to the NCP | | Descriptor: | DNA (145-MER), G2/mitotic-specific cyclin-B1, Histone H2A type 3, ... | | Authors: | Young, R.V.C, Muhammad, R, Alfieri, C. | | Deposit date: | 2024-05-27 | | Release date: | 2024-07-24 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Spatial control of the APC/C ensures the rapid degradation of cyclin B1.
Embo J., 43, 2024
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9C0I
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9C0J
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9FGQ
 | | Structure of human APC3loop 375-381 bound to the NCP | | Descriptor: | Cell division cycle protein 27 homolog, DNA (131-MER), DNA (132-MER), ... | | Authors: | Young, R.V.C, Muhammad, R, Alfieri, C. | | Deposit date: | 2024-05-24 | | Release date: | 2024-07-24 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Spatial control of the APC/C ensures the rapid degradation of cyclin B1.
Embo J., 43, 2024
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9FGP
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9BXA
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9FEH
 | | Crystal structure of SARS-CoV-2 nsp14 methyltransferase domain in complex with the STM957 inhibitor | | Descriptor: | Transcription factor ETV6,Guanine-N7 methyltransferase nsp14, ZINC ION, ~{N}-[[(2~{R},3~{S},4~{R},5~{R})-5-[4-azanyl-5-(2-pyridin-3-ylethynyl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-3-cyano-~{N}-ethyl-4-methoxy-benzenesulfonamide | | Authors: | Zilecka, E, Klima, M, Boura, E. | | Deposit date: | 2024-05-20 | | Release date: | 2024-08-28 | | Last modified: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39.
J Struct Biol X, 10, 2024
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9BVT
 | | RNA Pol II - High Mn(+2) concentration | | Descriptor: | DNA (5'-D(P*AP*CP*GP*TP*CP*CP*CP*TP*CP*TP*CP*GP*A)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | Authors: | Calero, G. | | Deposit date: | 2024-05-20 | | Release date: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Proc.Natl.Acad.Sci.USA, 121, 2024
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9BW0
 | | RNA Polymerase II - No ATP | | Descriptor: | DNA (5'-D(P*AP*CP*GP*TP*CP*CP*CP*TP*CP*TP*CP*GP*A)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | Authors: | Calero, G. | | Deposit date: | 2024-05-20 | | Release date: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (3.51 Å) | | Cite: | Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Proc.Natl.Acad.Sci.USA, 121, 2024
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9BW1
 | | TnsABCD-DNA transpososome | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Integrase, LE_polyA, ... | | Authors: | Chang, L, Wang, S. | | Deposit date: | 2024-05-20 | | Release date: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Structure of TnsABCD transpososome reveals mechanisms of targeted DNA transposition.
Cell, 2024
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9FEJ
 | | Structure of the RNA-dependent RNA polymerase P2 from the bacteriophage Phi8 | | Descriptor: | CALCIUM ION, RNA-directed RNA polymerase | | Authors: | Latimer-Smith, M, Salgado, P.S, Forsyth, I, Makeyev, E, Poranen, M, Stuart, D.I, Grimes, J.M, El Omari, K. | | Deposit date: | 2024-05-20 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the RNA-dependent RNA polymerase P2 from the bacteriophage Phi8
To Be Published
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9FEF
 | | Cryo-EM structure of Trypanosoma cruzi (MDH)4-PEX5 complex | | Descriptor: | Peroxisome targeting signal 1 receptor, malate dehydrogenase | | Authors: | Lipinski, O, Sonani, R.R, Blat, A, Jemiola-Rzeminska, M, Patel, S.N, Sood, T, Dubin, G. | | Deposit date: | 2024-05-19 | | Release date: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Cryo-EM structure of Trypanosoma cruzi (MDH)4-PEX5 complex
To Be Published
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8ZLD
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9BUN
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9BU5
 | | CC ProXp-ala apo solution structure | | Descriptor: | DNA-binding protein, putative | | Authors: | Duran, A.D, Foster, M.P. | | Deposit date: | 2024-05-16 | | Release date: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | NMR-based solution structure of the Caulobacter crescentus ProXp-ala trans-editing enzyme.
Biomol.Nmr Assign., 2024
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8ZJI
 | | Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 1) | | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | | Deposit date: | 2024-05-15 | | Release date: | 2024-06-26 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (4.23 Å) | | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.
J.Biol.Chem., 300, 2024
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