5LAE
| Crystal structure of murine N1-acetylpolyamine oxidase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase,Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | Authors: | Sjogren, T, Aagaard, A, Snijder, A, Barlind, L. | Deposit date: | 2016-06-14 | Release date: | 2017-03-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Structure of Murine N(1)-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism. Biochemistry, 56, 2017
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5MRL
| Crystal structure of human monoamine oxidase B (MAO B) in complex with N(Furan2ylmethyl)Nmethylprop2yn1amine (F2MPA) | Descriptor: | (~{E})-~{N}-(furan-2-ylmethyl)-~{N}-methyl-prop-1-en-1-amine, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Binda, C, De Deurwaerdere, P, Corne, R, Leone, C, Valeri, A, Valoti, M, Ramsay, R.R, Fall, Y, Marco-Contelles, J. | Deposit date: | 2016-12-23 | Release date: | 2017-01-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine. ACS Chem Neurosci, 8, 2017
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5LFO
| Crystal structure of murine N1-acetylpolyamine oxidase in complex with N1-acetylspermine | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamide, ... | Authors: | Sjogren, T, Aagaard, A, Wassvik, C, Snijder, A, Barlind, L. | Deposit date: | 2016-07-04 | Release date: | 2017-03-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | The Structure of Murine N(1)-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism. Biochemistry, 56, 2017
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5LGB
| Crystal structure of murine N1-acetylpolyamine oxidase in complex with MDL72527 | Descriptor: | FAD-MDL72527 adduct, N,N'-BIS(2,3-BUTADIENYL)-1,4-BUTANE-DIAMINE, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase,Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | Authors: | Sjogren, T, Aagaard, A, Wassvik, C, Snijder, A, Barlind, L. | Deposit date: | 2016-07-06 | Release date: | 2017-08-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Structure of Murine N(1)-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism. Biochemistry, 56, 2017
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5MOG
| Oryza sativa phytoene desaturase inhibited by norflurazon | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Brausemann, A, Gemmecker, S, Koschmieder, J, Beyer, P, Einsle, O. | Deposit date: | 2016-12-14 | Release date: | 2017-07-12 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Structure of Phytoene Desaturase Provides Insights into Herbicide Binding and Reaction Mechanisms Involved in Carotene Desaturation. Structure, 25, 2017
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5MBX
| Crystal structure of reduced murine N1-acetylpolyamine oxidase in complex with N1-acetylspermine | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamide, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, ... | Authors: | Sjogren, T, Aagaard, A, Wassvik, C, Snijder, A, Barlind, L. | Deposit date: | 2016-11-09 | Release date: | 2017-01-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The Structure of Murine N(1)-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism. Biochemistry, 56, 2017
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2XFN
| Human monoamine oxidase B in complex with 2-(2-benzofuranyl)-2- imidazoline | Descriptor: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-05-26 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2XFU
| Human monoamine oxidase B with tranylcypromine | Descriptor: | 3-PHENYLPROPANAL, Amine oxidase [flavin-containing] B, [[(2R,3S,4S)-5-[(4AS)-7,8-DIMETHYL-2,4-DIOXO-4A,5-DIHYDROBENZO[G]PTERIDIN-10-YL]-2,3,4-TRIHYDROXY-PENTOXY]-HYDROXY-PHOSPHORYL] [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL HYDROGEN PHOSPHATE | Authors: | Binda, C, Li, M, Hubalek, F, Restelli, N, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-05-26 | Release date: | 2010-06-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2XFO
| tranylcypromine-inhibited human monoamine oxidase B Ile199Ala mutant in complex with 2-(2-benzofuranyl)-2-imidazoline | Descriptor: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, 3-PHENYLPROPANAL, Amine oxidase [flavin-containing] B, ... | Authors: | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-05-26 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2YG7
| Structure-based redesign of cofactor binding in Putrescine Oxidase: A394C-A396T-Q431G Triple mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PUTRESCINE OXIDASE | Authors: | Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure-Based Redesign of Cofactor Binding in Putrescine Oxidase. Biochemistry, 50, 2011
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2YG3
| Structure-based redesign of cofactor binding in Putrescine Oxidase: wild type enzyme | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, PUTRESCINE OXIDASE, ... | Authors: | Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Based Redesign of Cofactor Binding in Putrescine Oxidase. Biochemistry, 50, 2011
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2YG4
| Structure-based redesign of cofactor binding in Putrescine Oxidase: wild type bound to Putrescine | Descriptor: | 4-HYDROXYBUTAN-1-AMINIUM, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Based Redesign of Cofactor Binding in Putrescine Oxidase. Biochemistry, 50, 2011
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2XFP
| Isatin-inhibited human monoamine oxidase B in complex with 2-(2- benzofuranyl)-2-imidazoline | Descriptor: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-05-26 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2XCG
| Tranylcypromine-inhibited human monoamine oxidase B in complex with 2- (2-benzofuranyl)-2-imidazoline | Descriptor: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, 3-PHENYLPROPANAL, Amine oxidase [flavin-containing] B, ... | Authors: | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-04-23 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2XFQ
| Rasagiline-inhibited human monoamine oxidase B in complex with 2-(2- benzofuranyl)-2-imidazoline | Descriptor: | (1R)-N-(prop-2-en-1-yl)-2,3-dihydro-1H-inden-1-amine, 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, Amine oxidase [flavin-containing] B, ... | Authors: | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-05-26 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2YG5
| Structure-based redesign of cofactor binding in Putrescine Oxidase: A394C mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, PUTRESCINE OXIDASE, ... | Authors: | Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-Based Redesign of Cofactor Binding in Putrescine Oxidase. Biochemistry, 50, 2011
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2Z5Y
| Crystal Structure of Human Monoamine Oxidase A (G110A) with Harmine | Descriptor: | 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, Amine oxidase [flavin-containing] A, DECYL(DIMETHYL)PHOSPHINE OXIDE, ... | Authors: | Son, S.Y, Ma, J, Yoshimura, M, Tsukihara, T. | Deposit date: | 2007-07-20 | Release date: | 2008-04-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structure of human monoamine oxidase A at 2.2-A resolution: The control of opening the entry for substrates/inhibitors Proc.Natl.Acad.Sci.Usa, 105, 2008
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2Z5X
| Crystal Structure of Human Monoamine Oxidase A with Harmine | Descriptor: | 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, Amine oxidase [flavin-containing] A, DECYL(DIMETHYL)PHOSPHINE OXIDE, ... | Authors: | Son, S.Y, Ma, J, Yoshimura, M, Tsukihara, T. | Deposit date: | 2007-07-20 | Release date: | 2008-04-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of human monoamine oxidase A at 2.2-A resolution: The control of opening the entry for substrates/inhibitors Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BI5
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3BI4
| Crystal structures of fms1 in complex with its inhibitors | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, N-[(1E,2Z)-but-2-en-1-ylidene]-N'-[(2E)-but-2-en-1-ylidene]butane-1,4-diamine, Polyamine oxidase FMS1 | Authors: | Huang, Q, Hao, Q. | Deposit date: | 2007-11-29 | Release date: | 2008-01-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of fms1 in complex with its inhibitors To be Published
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3BI2
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3BNM
| Crystal structure of polyamine oxidase FMS1 from Saccharomyces cerevisiae in complex with bis-(3R,3'R)-methylated spermine | Descriptor: | (3R,3'R)-N~1~,N~1~'-butane-1,4-diyldibutane-1,3-diamine, FLAVIN-ADENINE DINUCLEOTIDE, Polyamine oxidase FMS1 | Authors: | Huang, Q, Hao, Q. | Deposit date: | 2007-12-14 | Release date: | 2008-01-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of the substrate stereospecificity of FMS1. To Be Published
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2YG6
| Structure-based redesign of cofactor binding in Putrescine Oxidase: P15I-A394C double mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, PUTRESCINE OXIDASE, ... | Authors: | Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A. | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-based redesign of cofactor binding in putrescine oxidase. Biochemistry, 50, 2011
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2C64
| MAO inhibition by rasagiline analogues | Descriptor: | (1R)-6-HYDROXY-N-METHYL-N-[(1Z)-PROP-2-EN-1-YLIDENE]INDAN-1-AMINIUM, AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Binda, C, Hubalek, F, Li, M, Herzig, Y, Sterling, J, Edmondson, D.E, Mattevi, A. | Deposit date: | 2005-11-07 | Release date: | 2006-01-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding of Rasagiline-Related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis. J.Med.Chem., 48, 2005
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2BXR
| Human Monoamine Oxidase A in complex with Clorgyline, Crystal Form A | Descriptor: | AMINE OXIDASE [FLAVIN-CONTAINING] A, FLAVIN-ADENINE DINUCLEOTIDE, N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE | Authors: | De Colibus, L, Binda, C, Edmondson, D.E, Mattevi, A. | Deposit date: | 2005-07-27 | Release date: | 2005-08-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B Proc.Natl.Acad.Sci.USA, 102, 2005
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