PDB: 674 件ウェブページステータス検索Chemie searchBIRD

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6JRD	ZHD complex with hydrolyzed beta-ZOL 分子名称: 2-[(~{E},6~{S},10~{S})-6,10-bis(oxidanyl)undec-1-enyl]-4,6-bis(oxidanyl)benzoic acid, GLYCEROL, POTASSIUM ION, ... 著者 Hu, X.J. 登録日 2019-04-03 公開日 2020-04-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure of ZHD complex To Be Published
6JR2	ZHD/H242A complex with aZOL 分子名称: (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, GLYCEROL, POTASSIUM ION, ... 著者 Hu, X.J. 登録日 2019-04-02 公開日 2020-04-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure of ZHD complex To Be Published
2B61	Crystal Structure of Homoserine Transacetylase 分子名称: Homoserine O-acetyltransferase 著者 Mirza, I.A, Nazi, I, Korczynska, M, Wright, G.D, Berghuis, A.M. 登録日 2005-09-29 公開日 2005-11-15 最終更新日 2018-02-07 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal Structure of Homoserine Transacetylase from Haemophilus influenzae Reveals a New Family of alpha/beta-Hydrolases Biochemistry, 44, 2005
3IA2	Pseudomonas fluorescens esterase complexed to the R-enantiomer of a sulfonate transition state analog 分子名称: (2R)-butane-2-sulfonate, Arylesterase, GLYCEROL, ... 著者 Schrag, J.D, Kazlauskas, R.J, Jiang, Y, Morley, K. 登録日 2009-07-13 公開日 2010-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Different active-site loop orientation in serine hydrolases versus acyltransferases. Chembiochem, 12, 2011
3OOS	The structure of an alpha/beta fold family hydrolase from Bacillus anthracis str. Sterne 分子名称: Alpha/beta hydrolase family protein, GLYCEROL, SULFATE ION, ... 著者 Fan, Y, Tan, K, Bigelow, L, Hamilton, J, Li, H, Zhou, Y, Clancy, S, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2010-08-31 公開日 2010-11-10 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The structure of an alpha/beta fold family hydrolase from Bacillus anthracis str. Sterne To be Published
2D0D	Crystal Structure of a Meta-cleavage Product Hydrolase (CumD) A129V Mutant 分子名称: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, CHLORIDE ION, PHOSPHATE ION 著者 Jun, S.Y, Fushinobu, S, Nojiri, H, Omori, T, Shoun, H, Wakagi, T. 登録日 2005-08-01 公開日 2006-06-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Improving the catalytic efficiency of a meta-cleavage product hydrolase (CumD) from Pseudomonas fluorescens IP01 Biochim.Biophys.Acta, 1764, 2006
5Z7W	Crystal structure of Striga hermonthica HTL1 (ShHTL1) 分子名称: GLYCEROL, Hyposensitive to light 1, MAGNESIUM ION, ... 著者 Xu, Y, Miyakawa, T, Nakamura, A, Tanokura, M. 登録日 2018-01-30 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.657 Å) 主引用文献 Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga. Nat Commun, 9, 2018
6NY9	Alpha/beta hydrolase domain-containing protein 10 from mouse 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Mycophenolic acid acyl-glucuronide esterase, mitochondrial, ... 著者 Cao, Y, Rice, P.A, Dickinson, B.C. 登録日 2019-02-11 公開日 2020-01-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5. Nat.Chem.Biol., 15, 2019
4BRZ	Haloalkane dehalogenase 分子名称: CHLORIDE ION, HALOALKANE DEHALOGENASE 著者 Novak, H.R, Sayer, C, Isupov, M, Gotz, D, Spragg, A.M, Littlechild, J.A. 登録日 2013-06-06 公開日 2014-05-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Biochemical and Structural Characterisation of a Haloalkane Dehalogenase from a Marine Rhodobacteraceae. FEBS Lett., 588, 2014
4Y7D	Alpha/beta hydrolase fold protein from Nakamurella multipartita 分子名称: Alpha/beta hydrolase fold protein, CHLORIDE ION, SODIUM ION 著者 Cuff, M.E, OSIPIUK, J, Holowicki, J, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2015-02-14 公開日 2015-02-25 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Alpha/beta hydrolase fold protein from Nakamurella multipartita. to be published
7ZBD	HaloTag with TRaQ-G ligand 分子名称: (10R)-7-azanyl-N-[2-[2-(6-chloranylhexoxy)ethoxy]ethyl]-2'-cyano-5,5-dimethyl-3-(methylamino)-1'-oxidanylidene-spiro[benzo[b][1]benzosiline-10,3'-isoindole]-5'-carboxamide, CHLORIDE ION, GLYCEROL, ... 著者 Emmert, S, Rivera-Fuentes, P, Pojer, F, Lau, K. 登録日 2022-03-23 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 A locally activatable sensor for robust quantification of organellar glutathione. Nat.Chem., 15, 2023
3QIT	Thioesterase Domain From Curacin Biosynthetic Pathway 分子名称: Polyketide synthase 著者 Gehret, J.J, Smith, J.L. 登録日 2011-01-27 公開日 2011-03-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis: STRUCTURE OF A DECARBOXYLATING THIOESTERASE. J.Biol.Chem., 286, 2011
2RI6	Crystal Structure of S112A mutant of a C-C hydrolase, BphD from Burkholderia xenovorans LB400 分子名称: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, MALONATE ION, SODIUM ION 著者 Bhowmik, S, Bolin, J.T. 登録日 2007-10-10 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 The tautomeric half-reaction of BphD, a C-C bond hydrolase. Kinetic and structural evidence supporting a key role for histidine 265 of the catalytic triad. J.Biol.Chem., 282, 2007
4WCV	Haloalkane dehalogenase DhaA mutant from Rhodococcus rhodochrous (T148L+G171Q+A172V+C176G) 分子名称: ACETATE ION, CHLORIDE ION, Haloalkane dehalogenase, ... 著者 Holubeva, T, Prudnikova, T, Kuta-Smatanova, I, Rezacova, P. 登録日 2014-09-05 公開日 2014-10-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Balancing the stability-activity trade-off by fine-tuning dehalogenase access tunnels Chemcatchem, 2015
4I3F	Crystal structure of serine hydrolase CCSP0084 from the polyaromatic hydrocarbon (PAH)-degrading bacterium Cycloclasticus zankles 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... 著者 Stogios, P.J, Xu, X, Dong, A, Cui, H, Alcaide, M, Tornes, J, Gertler, C, Yakimov, M.M, Golyshin, P.N, Ferrer, M, Savchenko, A. 登録日 2012-11-26 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Single residues dictate the co-evolution of dual esterases: MCP hydrolases from the alpha / beta hydrolase family. Biochem.J., 454, 2013
5W8P	Homoserine transacetylase MetX from Mycobacterium abscessus 分子名称: GLYCEROL, Homoserine O-acetyltransferase, PHOSPHATE ION, ... 著者 Rodriguez, E.S, Reed, R.W, Korotkov, K.V. 登録日 2017-06-22 公開日 2017-07-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site. Sci Rep, 9, 2019
6QHY	Time resolved structural analysis of the full turnover of an enzyme - 100 ms 分子名称: Fluoroacetate dehalogenase, fluoroacetic acid 著者 Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. 登録日 2019-01-17 公開日 2019-09-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
3R3Z	Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT/Glycolate 分子名称: Fluoroacetate dehalogenase, GLYCOLIC ACID, NICKEL (II) ION 著者 Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. 登録日 2011-03-16 公開日 2011-05-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mapping the reaction coordinates of enzymatic defluorination. J.Am.Chem.Soc., 133, 2011
6XT8	Crystal structure of haloalkane dehalogenase variant DhaA115 domain-swapped dimer type-2 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... 著者 Markova, K, Damborsky, J, Marek, M. 登録日 2020-01-15 公開日 2021-01-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers Acs Catalysis, 11, 2021
5AM2	ligand complex structure of soluble epoxide hydrolase 分子名称: 7-METHYL-2H-ISOQUINOLIN-1-ONE, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-08 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
1UK7	Crystal structure of a meta-cleavage product hydrolase (CumD) complexed with n-butyrate 分子名称: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, butanoic acid 著者 Fushinobu, S, Jun, S.-Y, Hidaka, M, Nojiri, H, Yamane, H, Shoun, H, Omori, T, Wakagi, T. 登録日 2003-08-19 公開日 2004-09-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A Series of Crystal Structures of a meta-Cleavage Product Hydrolase from Pseudomonas fluorescens IP01 (CumD) Complexed with Various Cleavage Products BIOSCI.BIOTECHNOL.BIOCHEM., 69, 2005
1UKA	Crystal structure of a meta-cleavage product hydrolase (CumD) complexed with (S)-2-methylbutyrate 分子名称: 2-METHYLBUTANOIC ACID, 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase 著者 Fushinobu, S, Jun, S.-Y, Hidaka, M, Nojiri, H, Yamane, H, Shoun, H, Omori, T, Wakagi, T. 登録日 2003-08-19 公開日 2004-09-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A Series of Crystal Structures of a meta-Cleavage Product Hydrolase from Pseudomonas fluorescens IP01 (CumD) Complexed with Various Cleavage Products BIOSCI.BIOTECHNOL.BIOCHEM., 69, 2005
6T6Z	Structure of the Bottromycin epimerase BotH in complex with a bottromycin A2 derivative 分子名称: BotH, Bottromycin A2 derivative 著者 Koehnke, J, Sikandar, A. 登録日 2019-10-20 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The bottromycin epimerase BotH defines a group of atypical alpha / beta-hydrolase-fold enzymes. Nat.Chem.Biol., 16, 2020
1QGE	NEW CRYSTAL FORM OF PSEUDOMONAS GLUMAE (FORMERLY CHROMOBACTERIUM VISCOSUM ATCC 6918) LIPASE 分子名称: CALCIUM ION, PROTEIN (TRIACYLGLYCEROL HYDROLASE) 著者 Lang, D.A, Stadler, P, Kovacs, A, Paltauf, F, Dijkstra, B.W. 登録日 1999-04-27 公開日 1999-05-06 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and Kinetic Investigations of Enantiomeric Binding Mode of Subclass I Lipases from the Family of Pseudomonadaceae To be Published
7ZIY	X-ray structure of the haloalkane dehalogenase HaloTag7 bound to a pentyltrifluoromethanesulfonamide tetramethylrhodamine ligand (TMR-T5) 分子名称: CALCIUM ION, Haloalkane dehalogenase, [9-[2-carboxy-5-[2-[2-[5-(trifluoromethylsulfonylamino)pentoxy]ethoxy]ethylcarbamoyl]phenyl]-6-(dimethylamino)xanthen-3-ylidene]-dimethyl-azanium 著者 Tarnawski, M, Kompa, J, Johnsson, K, Hiblot, J. 登録日 2022-04-08 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Exchangeable HaloTag Ligands for Super-Resolution Fluorescence Microscopy. J.Am.Chem.Soc., 145, 2023

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