7O71
| Cryo-EM structure of a respiratory complex I | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | Authors: | Parey, K, Vonck, J. | Deposit date: | 2021-04-12 | Release date: | 2021-11-10 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Sci Adv, 7, 2021
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7O6Y
| Cryo-EM structure of respiratory complex I under turnover | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | Authors: | Parey, K, Vonck, J. | Deposit date: | 2021-04-12 | Release date: | 2021-11-10 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Sci Adv, 7, 2021
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7NYV
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7NYU
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7NYR
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7NYH
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7B93
| Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-5-[3-[4-(trifluoromethyloxy)phenyl]-1,2,4-oxadiazol-5-yl]pyridin-2-one, ... | Authors: | Chung, I, Hirst, J. | Deposit date: | 2020-12-14 | Release date: | 2021-05-26 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Cork-in-bottle mechanism of inhibitor binding to mammalian complex I. Sci Adv, 7, 2021
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7DKF
| Activity optimized supercomplex state4 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Jeon, T.J, Lee, S.G, Yoo, S.H, Ryu, J.H, Kim, D.S, Hyun, J.K, Kim, H.M, Ryu, S.E. | Deposit date: | 2020-11-24 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (8.3 Å) | Cite: | A Dynamic Substrate Pool Revealed by cryo-EM of a Lipid-Preserved Respiratory Supercomplex. Antioxid.Redox Signal., 2022
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7B0N
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7DH0
| Activity optimized complex I (open form) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Jeon, T.J, Lee, S.G, Yoo, S.H, Ryu, J.H, Kim, D.S, Hyun, J.K, Kim, H.M, Ryu, S.E. | Deposit date: | 2020-11-12 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | A Dynamic Substrate Pool Revealed by cryo-EM of a Lipid-Preserved Respiratory Supercomplex. Antioxid.Redox Signal., 2022
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7DGZ
| Activity optimized complex I (closed form) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Jeon, T.J, Lee, S.G, Yoo, S.H, Ryu, J.H, Kim, D.S, Hyun, J.K, Kim, H.M, Ryu, S.E. | Deposit date: | 2020-11-12 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A Dynamic Substrate Pool Revealed by cryo-EM of a Lipid-Preserved Respiratory Supercomplex. Antioxid.Redox Signal., 2022
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7DGS
| Activity optimized supercomplex state3 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Jeon, T.J, Lee, S.G, Yoo, S.H, Ryu, J.H, Kim, D.S, Hyun, J.K, Kim, H.M, Ryu, S.E. | Deposit date: | 2020-11-12 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | A Dynamic Substrate Pool Revealed by cryo-EM of a Lipid-Preserved Respiratory Supercomplex. Antioxid.Redox Signal., 2022
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7DGR
| Activity optimized supercomplex state2 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Jeon, T.J, Lee, S.G, Yoo, S.H, Ryu, J.H, Kim, D.S, Hyun, J.K, Kim, H.M, Ryu, S.E. | Deposit date: | 2020-11-12 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | A Dynamic Substrate Pool Revealed by cryo-EM of a Lipid-Preserved Respiratory Supercomplex. Antioxid.Redox Signal., 2022
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7DGQ
| Activity optimized supercomplex state1 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Jeon, T.J, Lee, S.G, Yoo, S.H, Ryu, J.H, Kim, D.S, Hyun, J.K, Kim, H.M, Ryu, S.E. | Deposit date: | 2020-11-12 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | A Dynamic Substrate Pool Revealed by cryo-EM of a Lipid-Preserved Respiratory Supercomplex. Antioxid.Redox Signal., 2022
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7AQW
| Cryo-EM structure of Arabidopsis thaliana Complex-I (membrane tip) | Descriptor: | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Acyl carrier protein 1, mitochondrial, ... | Authors: | Klusch, N, Kuehlbrandt, W, Yildiz, O. | Deposit date: | 2020-10-23 | Release date: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | A ferredoxin bridge connects the two arms of plant mitochondrial complex I. Plant Cell, 33, 2021
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7AR9
| Cryo-EM structure of Polytomella Complex-I (membrane arm) | Descriptor: | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 15 kDa, AGGG, ... | Authors: | Klusch, N, Kuehlbrandt, W, Yildiz, O. | Deposit date: | 2020-10-23 | Release date: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | A ferredoxin bridge connects the two arms of plant mitochondrial complex I. Plant Cell, 33, 2021
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7AR8
| Cryo-EM structure of Arabidopsis thaliana complex-I (closed conformation) | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | Authors: | Klusch, N, Kuelbrandt, W, Yildiz, O. | Deposit date: | 2020-10-23 | Release date: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | A ferredoxin bridge connects the two arms of plant mitochondrial complex I. Plant Cell, 33, 2021
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7ARB
| Cryo-EM structure of Arabidopsis thaliana Complex-I (complete composition) | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | Authors: | Klusch, N, Kuelbrandt, W, Yildiz, O. | Deposit date: | 2020-10-23 | Release date: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | A ferredoxin bridge connects the two arms of plant mitochondrial complex I. Plant Cell, 33, 2021
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7AR7
| Cryo-EM structure of Arabidopsis thaliana complex-I (open conformation) | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | Authors: | Klusch, N, Kuelbrandt, W. | Deposit date: | 2020-10-23 | Release date: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | A ferredoxin bridge connects the two arms of plant mitochondrial complex I. Plant Cell, 33, 2021
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7AQQ
| Cryo-EM structure of Arabidopsis thaliana Complex-I (membrane core) | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | Authors: | Klusch, N, Kuehlbrandt, W, Yildiz, O. | Deposit date: | 2020-10-22 | Release date: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | A ferredoxin bridge connects the two arms of plant mitochondrial complex I. Plant Cell, 33, 2021
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7AK6
| Cryo-EM structure of ND6-P25L mutant respiratory complex I from Mus musculus at 3.8 A | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Yin, Z, Bridges, H.R, Grba, D, Hirst, J. | Deposit date: | 2020-09-29 | Release date: | 2021-02-03 | Last modified: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structural basis for a complex I mutation that blocks pathological ROS production. Nat Commun, 12, 2021
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7AK5
| Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Yin, Z, Bridges, H.R, Grba, D, Hirst, J. | Deposit date: | 2020-09-29 | Release date: | 2021-02-03 | Last modified: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Structural basis for a complex I mutation that blocks pathological ROS production. Nat Commun, 12, 2021
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7D3U
| Structure of Mrp complex from Dietzia sp. DQ12-45-1b | Descriptor: | Cation antiporter, DODECYL-BETA-D-MALTOSIDE, Monovalent Na+/H+ antiporter subunit A, ... | Authors: | Li, B, Zhang, K.D, Wu, X.L, Zhang, X.C. | Deposit date: | 2020-09-21 | Release date: | 2020-12-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the Dietzia Mrp complex reveals molecular mechanism of this giant bacterial sodium proton pump. Proc.Natl.Acad.Sci.USA, 117, 2020
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7A24
| Assembly intermediate of the plant mitochondrial complex I | Descriptor: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 13kDa, 15kDa, ... | Authors: | Soufari, H, Waltz, F, Hashem, Y. | Deposit date: | 2020-08-16 | Release date: | 2020-10-28 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM. Nat Commun, 11, 2020
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7A23
| Plant mitochondrial respiratory complex I | Descriptor: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 13kDa, 15kDa, ... | Authors: | Soufari, H, Waltz, F, Hashem, Y. | Deposit date: | 2020-08-15 | Release date: | 2020-10-28 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM. Nat Commun, 11, 2020
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