3UVP
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![BU of 3uvp by Molmil](/molmil-images/mine/3uvp) | Human p38 MAP Kinase in Complex with a Benzamide Substituted Benzosuberone | Descriptor: | Mitogen-activated protein kinase 14, N-{2-fluoro-5-[(5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino]phenyl}benzamide, octyl beta-D-glucopyranoside | Authors: | Mayer-Wrangowski, S.C, Richters, A, Gruetter, C, Rauh, D. | Deposit date: | 2011-11-30 | Release date: | 2012-11-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Targeting the Hinge Glycine Flip and the Activation Loop: Novel Approach to Potent p38 alpha Inhibitors. J.Med.Chem., 55, 2012
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3UW1
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3UQU
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![BU of 3uqu by Molmil](/molmil-images/mine/3uqu) | Crystal structure of BACE1 with its inhibitor | Descriptor: | Beta-secretase 1, CHLORIDE ION, N-[(1R)-1-(4-fluorophenyl)ethyl]-N'-[(2S,3S)-3-hydroxy-1-phenyl-4-(1H-pyrazol-1-yl)butan-2-yl]-5-[methyl(methylsulfonyl)amino]benzene-1,3-dicarboxamide, ... | Authors: | Chen, T.T, Chen, W.Y, Xu, Y.C. | Deposit date: | 2011-11-21 | Release date: | 2012-11-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Flexibility of the Flap in the Active Site of BACE1 as Revealed by Crystal Structures and MD simulations to be published
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3V51
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3V5J
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3V5P
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3UW2
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![BU of 3uw2 by Molmil](/molmil-images/mine/3uw2) | |
3V60
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3UWS
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3SX8
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![BU of 3sx8 by Molmil](/molmil-images/mine/3sx8) | Crystal structure of ABBA+UDP+Gal with MPD as the cryoprotectant | Descriptor: | DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Johal, A.R, Evans, S.V. | Deposit date: | 2011-07-14 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases. Acta Crystallogr.,Sect.D, 68, 2012
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3SXE
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![BU of 3sxe by Molmil](/molmil-images/mine/3sxe) | Crystal structure of AAAA+UDP+Gal with Glycerol as the cryoprotectant | Descriptor: | Histo-blood group ABO system transferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Johal, A.R, Evans, S.V. | Deposit date: | 2011-07-14 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases. Acta Crystallogr.,Sect.D, 68, 2012
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3SS6
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![BU of 3ss6 by Molmil](/molmil-images/mine/3ss6) | Crystal structure of the Bacillus anthracis acetyl-CoA acetyltransferase | Descriptor: | Acetyl-CoA acetyltransferase, POTASSIUM ION, SULFATE ION | Authors: | Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-07-07 | Release date: | 2011-07-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the Bacillus anthracis acetyl-CoA acetyltransferase TO BE PUBLISHED
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3SYP
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3STC
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3STW
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3T00
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3SY3
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![BU of 3sy3 by Molmil](/molmil-images/mine/3sy3) | GBAA_1210 protein, a putative adenylate cyclase, from Bacillus anthracis | Descriptor: | GBAA_1210 protein, PHOSPHATE ION | Authors: | Osipiuk, J, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-07-15 | Release date: | 2011-07-27 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | GBAA_1210 protein, a putative adenylate cyclase, from Bacillus anthracis. To be Published
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3SYO
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![BU of 3syo by Molmil](/molmil-images/mine/3syo) | Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with sodium | Descriptor: | G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, SODIUM ION | Authors: | Whorton, M.R, MacKinnon, R. | Deposit date: | 2011-07-18 | Release date: | 2011-10-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.54 Å) | Cite: | Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium. Cell(Cambridge,Mass.), 147, 2011
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3T6C
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![BU of 3t6c by Molmil](/molmil-images/mine/3t6c) | Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, D-gluconic acid, ... | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2011-07-28 | Release date: | 2011-08-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.598 Å) | Cite: | Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg to be published
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3T8U
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![BU of 3t8u by Molmil](/molmil-images/mine/3t8u) | Crystal structure of ketosteroid isomerase Y14AY55FD99A from Pseudomonas testosteroni | Descriptor: | SULFATE ION, Steroid Delta-isomerase | Authors: | Gonzalez, A, Tsai, Y, Schwans, J, Sunden, F, Herschlag, D. | Deposit date: | 2011-08-01 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Evaluating the catalytic contribution from the oxyanion hole in ketosteroid isomerase. J.Am.Chem.Soc., 133, 2011
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3T27
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![BU of 3t27 by Molmil](/molmil-images/mine/3t27) | Orthorhombic trypsin (bovine) in the presence of betaine | Descriptor: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | Authors: | Venkat, M, Saxby, C, Cahn, J, Juers, D. | Deposit date: | 2011-07-22 | Release date: | 2011-12-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
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3TAW
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3T55
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![BU of 3t55 by Molmil](/molmil-images/mine/3t55) | Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with Phenoxymethyl Benzoic Acid (PMBA) | Descriptor: | 3-(phenoxymethyl)benzoic acid, Indole-3-glycerol phosphate synthase, MALONATE ION, ... | Authors: | Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2011-07-26 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published
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3TBJ
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![BU of 3tbj by Molmil](/molmil-images/mine/3tbj) | The 1.7A crystal structure of Actibind a T2 ribonucleases as antitumorigenic agents | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Almog, O, Gonzalez, A. | Deposit date: | 2011-08-07 | Release date: | 2012-08-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The 1.8 A crystal structure of ACTIBIND suggests a mode of action for T2 ribonucleases as antitumorigenic agents. J.Med.Chem., 55, 2012
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3SOX
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![BU of 3sox by Molmil](/molmil-images/mine/3sox) | Structure of UHRF1 PHD finger in the free form | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION | Authors: | Rajakumara, E, Patel, D.J. | Deposit date: | 2011-06-30 | Release date: | 2011-08-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6501 Å) | Cite: | PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression. Mol.Cell, 43, 2011
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