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7TH2
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BU of 7th2 by Molmil
Single-domain VHH intrabodies neutralize ricin toxin
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Rudolph, M.J, Mantis, N.
登録日2022-01-10
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.838 Å)
主引用文献Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins.
J.Biol.Chem., 298, 2022
4FBA
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Structure of mutant RIP from barley seeds in complex with adenine
分子名称: ADENINE, Protein synthesis inhibitor I
著者Lee, B.-G, Kim, M.K, Suh, S.W, Song, H.K.
登録日2012-05-22
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the ribosome-inactivating protein from barley seeds reveal a unique activation mechanism.
Acta Crystallogr.,Sect.D, 68, 2012
3U6T
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BU of 3u6t by Molmil
Crystal structure of the complex of type I Ribosome inactivating protein in complex with Kanamycin at 1.85 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, KANAMYCIN A, ...
著者Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
登録日2011-10-13
公開日2011-11-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the complex of type I Ribosome inactivating protein in complex with Kanamycin at 1.85 A
To be Published
4JTP
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Crystal structure of Ribosome inactivating protein from Momordica balsamina complexed with Ascorbic acid at 1.85 Angstrom resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ASCORBIC ACID, rRNA N-glycosidase
著者Pandey, S, Bhushan, A, Singh, A, Tyagi, T.K, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
登録日2013-03-24
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of Ribosome inactivating protein from Momordica balsamina complexed with Ascorbic acid at 1.85 Angstrom resolution
TO BE PUBLISHED
1QD2
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CRYSTAL STRUCTURE OF THE COMPLEX OF TRICHOSANTHIN WITH ADENINE, OBTAINED FROM TRICHOSANTHIN COMPLEXED WITH THE DINUCLEOTIDE APG
分子名称: ADENINE, TRICHOSANTHIN
著者Gu, Y.J, Xia, Z.X.
登録日1999-07-09
公開日2000-04-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structures of the complexes of trichosanthin with four substrate analogs and catalytic mechanism of RNA N-glycosidase.
Proteins, 39, 2000
4HV7
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BU of 4hv7 by Molmil
Structure of ricin A chain bound with N-(N-(pterin-7-yl)carbonylglycyl)glycine
分子名称: 2-[2-[(2-azanyl-4-oxidanylidene-1H-pteridin-7-yl)carbonylamino]ethanoylamino]ethanoic acid, MALONIC ACID, Ricin, ...
著者Jasheway, K.R, Monzingo, A.F, Saito, R, Pruet, J.M, Manzano, L.A, Wiget, P.A, Anslyn, E.V, Robertus, J.D.
登録日2012-11-05
公開日2012-12-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.869 Å)
主引用文献Peptide-conjugated pterins as inhibitors of ricin toxin A.
J.Med.Chem., 56, 2013
4ESI
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BU of 4esi by Molmil
Structure of ricin A chain bound with N-((1H-1,2,3-triazol-4-yl)methyl-2-amino-4-oxo-3,4-dihydropteridine-7-carboxamide
分子名称: 2-amino-4-oxo-N-(1H-1,2,3-triazol-5-ylmethyl)-1,4-dihydropteridine-7-carboxamide, Ricin
著者Jasheway, K.R, Pruet, J.M, Ryoto, S, Manzano, L.A, Wiget, P.A, Kamat, I, Anslyn, E.V, Monzingo, A.F, Robertus, J.D.
登録日2012-04-23
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Optimized 5-membered heterocycle-linked pterins for the inhibition of Ricin Toxin A.
ACS Med Chem Lett, 3, 2012
6X6H
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BU of 6x6h by Molmil
Structure of Shiga toxin 2 with a C-terminal peptide of ribosomal P stalk proteins
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ...
著者Rudolph, M.J.
登録日2020-05-28
公開日2020-09-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural basis for the interaction of Shiga toxin 2a with a C-terminal peptide of ribosomal P stalk proteins.
J.Biol.Chem., 295, 2020
5CIX
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BU of 5cix by Molmil
Structure of the complex of type 1 Ribosome inactivating protein with triethanolamine at 1.88 Angstrom resolution
分子名称: 2,2',2''-NITRILOTRIETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ...
著者Singh, P.K, Pandey, S, Tyagi, T.K, Singh, A, Kaur, P, Sharma, S, Singh, T.P.
登録日2015-07-13
公開日2015-08-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structure of the complex of type 1 Ribosome inactivating protein with triethanolamine at 1.88 Angstrom resolution.
To Be Published
3PX9
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RTA in complex with N-(furanylmethyl)-7-carbamoyl-pterin
分子名称: 2-amino-N-(furan-2-ylmethyl)-4-oxo-3,4-dihydropteridine-7-carboxamide, Preproricin
著者Jasheway, K.R, Robertus, J.D.
登録日2010-12-09
公開日2011-06-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献7-Substituted pterins provide a new direction for ricin A chain inhibitors.
Eur.J.Med.Chem., 46, 2011
1M2T
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Mistletoe Lectin I from Viscum album in Complex with Adenine Monophosphate. Crystal Structure at 1.9 A Resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, GLYCEROL, ...
著者Krauspenhaar, R, Rypniewski, W, Kalkura, N, Moore, K, DeLucas, L, Stoeva, S, Mikhailov, A, Voelter, W, Betzel, C.
登録日2002-06-25
公開日2003-06-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystallisation under microgravity of mistletoe lectin I from Viscum album with adenine monophosphate and the crystal structure at 1.9 A resolution.
Acta Crystallogr.,Sect.D, 58, 2002
4KL4
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BU of 4kl4 by Molmil
Crystal structure of Ribosome inactivating protein from Momordica balsamina complexed with Polyethylene glycol at 1.90 Angstrom resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Pandey, S, Tyagi, T.K, Singh, A, Bhushan, A, Kushwaha, G.S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
登録日2013-05-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Ribosome inactivating protein from Momordica balsamina complexed with Polyethylene glycol at 1.90 Angstrom resolution
To be Published
6OBO
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BU of 6obo by Molmil
Ricin A chain bound to VHH antibody V6A6
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ...
著者Rudolph, M.J.
登録日2019-03-21
公開日2020-04-01
最終更新日2020-10-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
1J1R
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BU of 1j1r by Molmil
Structure of Pokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with Adenine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Antiviral Protein S
著者Watanabe, K, Sato, E, Honjo, E, Motoshima, H, Kurokawa, H, Mikami, B, Monzingo, A.F, Robertus, J.D, Fujii, H, Hidaka, A.
登録日2002-12-14
公開日2004-02-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Pokweed Antiviral Protein from Seeds (PAP-S1) at 1.8 Angstrom Resolution
To be published
3N5D
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BU of 3n5d by Molmil
Crystal structure of the complex of type I ribosome inactivating protein with glucose at 1.9A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ribosome inactivating protein, ...
著者Pandey, N, Kushwaha, G.S, Sinha, M, Kaur, P, Betzel, C, Sharma, S, Singh, T.P.
登録日2010-05-25
公開日2010-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the complex of type I ribosome inactivating protein with glucose at 1.9A resolution
To be Published
1UQ4
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BU of 1uq4 by Molmil
RICIN A-CHAIN (RECOMBINANT) R213D MUTANT
分子名称: RICIN, SULFATE ION
著者Marsden, C.J, Fulop, V.
登録日2003-10-15
公開日2004-01-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Effect of Mutations Surrounding and within the Active Site on the Catalytic Activity of Ricin a Chain
Eur.J.Biochem., 271, 2004
7VHE
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BU of 7vhe by Molmil
Crystal structure of the STX2a complexed with RRRA peptide
分子名称: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, GLYCEROL, RRRA peptide, ...
著者Senda, M, Takahashi, M, Nishikawa, K, Senda, T.
登録日2021-09-22
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin.
Sci Rep, 12, 2022
5WV1
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BU of 5wv1 by Molmil
Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with ribose sugar at 1.90 A resolution.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ribosome inactivating protein, ...
著者Shokeen, A, Singh, P.K, Pandey, S, Kaur, P, Sharma, S, Singh, T.P.
登録日2016-12-21
公開日2017-01-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with ribose sugar at 1.90 A resolution.
To Be Published
3KU0
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BU of 3ku0 by Molmil
Structure of GAP31 with adenine at its binding pocket
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Ribosome-inactivating protein gelonin
著者Kong, X.-P.
登録日2009-11-26
公開日2010-01-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions.
Biochem.Biophys.Res.Commun., 391, 2010
3RL9
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BU of 3rl9 by Molmil
Crystal Structure of the complex of type I RIP with the hydrolyzed product of dATP, adenine at 1.9 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, GLYCEROL, ...
著者Kushwaha, G.S, Pandey, N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
登録日2011-04-19
公開日2011-05-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states
Biochim.Biophys.Acta, 1824, 2012
8CX8
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Stx2A1-BTB13086
分子名称: 1,2-ETHANEDIOL, 5-(4-chlorophenyl)furan-2-carboxylic acid, CHLORIDE ION, ...
著者Rudolph, M.J, Li, X.P.
登録日2022-05-20
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.905 Å)
主引用文献Stx2A1-BTB13086
To Be Published
1NLI
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Complex of [E160A-E189A] trichosanthin and adenine
分子名称: ADENINE, Ribosome-inactivating protein alpha-trichosanthin
著者Shaw, P.C, Wong, K.B, Chan, D.S.B, Williams, R.L.
登録日2003-01-07
公開日2003-01-21
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural basis for the interaction of [E160A-E189A]-trichosanthin with adenine.
Toxicon, 41, 2003
2P8N
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Ricin a-chain (recombinant) complex with adenine
分子名称: ADENINE, Ricin A chain, SULFATE ION
著者Carra, J.H, Mchugh, C.A, Mulligan, S, Machiesky, L.M, Millard, C.B.
登録日2007-03-22
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site
BMC Struct.Biol., 7, 2007
4EB2
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Crystal structure Mistletoe Lectin I from Viscum album in complex with n-acetyl-d-glucosamine at 1.94 A resolution.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Laskov, A.A, Prokofev, I.I, Gabdoulkhakov, A.G, Betzel, C, Mikhailov, A.M.
登録日2012-03-23
公開日2013-03-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure Mistletoe Lectin I from Viscum album in complex with N-acetyl-D-glucosamine at 1.94 A resolution.
To be Published
5GZ7
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Crystal Structure of the complex of Ribosome Inactivating Protein with 1,2-ethanediol at 1.95 Angstrom resolution
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Tiwari, P, Pandey, S.N, Kaur, P, Sharma, S, Singh, T.P.
登録日2016-09-26
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of the complex of Ribosome Inactivating Protein with 1,2-ethanediol at 1.95 Angstrom resolution.
To Be Published

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件を2024-04-24に公開中

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