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7FEW
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BU of 7few by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cAMP-activated global transcriptional regulator Vfr
著者Chew, B.L.A, Luo, D.
登録日2021-07-22
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7FF0
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BU of 7ff0 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GOLD ION, SULFATE ION, ...
著者Chew, B.L.A, Luo, D.
登録日2021-07-22
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7FF8
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BU of 7ff8 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
著者Chew, B.L.A, Luo, D.
登録日2021-07-22
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
7ETS
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BU of 7ets by Molmil
Crystal structure of crp protein from Gardnerella Vaginalis
分子名称: Crp/Fnr family transcriptional regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Dong, H.J, Wang, S, Zhang, J.M, Gu, L.
登録日2021-05-13
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Crystal structure of crp protein from Gardnerella Vaginalis
To Be Published
1ZRE
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BU of 1zre by Molmil
4 crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-[6G;17C]ICAP38 DNA
分子名称: 5'-D(*AP*TP*TP*TP*CP*GP*AP*AP*AP*AP*AP*TP*GP*GP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*CP*CP*AP*TP*TP*TP*TP*TP*CP*GP*AP*AP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
著者Berman, H.M, Napoli, A.A.
登録日2005-05-19
公開日2006-03-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps.
J.Mol.Biol., 357, 2006
1ZRC
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BU of 1zrc by Molmil
4 Crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-ICAP38 DNA
分子名称: 5'-D(*AP*TP*TP*TP*CP*GP*AP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*TP*CP*GP*AP*AP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
著者Berman, H.M, Napoli, A.A.
登録日2005-05-19
公開日2006-03-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps.
J.Mol.Biol., 357, 2006
1ZYB
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BU of 1zyb by Molmil
Crystal structure of transcription regulator from Bacteroides thetaiotaomicron VPI-5482 at 2.15 A resolution
分子名称: GLYCEROL, transcription regulator, CRP family
著者Joint Center for Structural Genomics (JCSG)
登録日2005-06-09
公開日2005-07-19
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of transcription regulator from Bacteroides thetaiotaomicron VPI-5482 at 2.15 A resolution
To be published
1ZRF
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BU of 1zrf by Molmil
4 crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-[6C;17G]ICAP38 DNA
分子名称: 1,4-DIETHYLENE DIOXIDE, 5'-D(*AP*TP*TP*TP*CP*GP*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*TP*CP*GP*AP*AP*AP*T)-3', ...
著者Berman, H.M, Napoli, A.A.
登録日2005-05-19
公開日2006-03-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps.
J.Mol.Biol., 357, 2006
1ZRD
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BU of 1zrd by Molmil
4 crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-[6A;17T]ICAP38 DNA
分子名称: 5'-D(*AP*TP*TP*TP*CP*GP*AP*AP*AP*AP*AP*TP*GP*AP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*TP*CP*AP*TP*TP*TP*TP*TP*CP*GP*AP*AP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
著者Berman, H.M, Napoli, A.A.
登録日2005-05-19
公開日2006-03-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps.
J.Mol.Biol., 357, 2006
2OZ6
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BU of 2oz6 by Molmil
Crystal Structure of Virulence Factor Regulator from Pseudomonas aeruginosa in complex with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Virulence Factor Regulator
著者Cordes, T.J, Bright, A.R, Forest, K.T.
登録日2007-02-24
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Pseudomonas aeruginosa Virulence Factor Regulator.
J.Bacteriol., 193, 2011
2HKX
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BU of 2hkx by Molmil
Structure of CooA mutant (N127L/S128L) from Carboxydothermus hydrogenoformans
分子名称: CARBON MONOXIDE, Carbon monoxide oxidation system transcription regulator CooA-1, PROTOPORPHYRIN IX CONTAINING FE
著者Lanz, N.D, Borjigin, M, Li, H, Kerby, R.L, Poulos, T.L, Roberts, G.P.
登録日2006-07-05
公開日2007-03-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-based hypothesis on the activation of the CO-sensing transcription factor CooA.
Acta Crystallogr.,Sect.D, 63, 2007
6CJT
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BU of 6cjt by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cGMP
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CYCLIC GUANOSINE MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel
著者Nimigean, C.M, Rheinberger, J.
登録日2018-02-26
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
6CJU
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BU of 6cju by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cAMP
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel
著者Nimigean, C.M, Rheinberger, J.
登録日2018-02-26
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
6CJQ
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BU of 6cjq by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, SthK cyclic nucleotide-gated potassium channel
著者Nimigean, C.M, Rheinberger, J.
登録日2018-02-26
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
6DT4
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BU of 6dt4 by Molmil
1.8 Angstrom Resolution Crystal Structure of cAMP-Regulatory Protein from Yersinia pestis in Complex with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, Cyclic AMP receptor protein
著者Minasov, G, Shuvalova, L, Kiryukhina, O, Ritzert, J.T.H, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-06-15
公開日2018-06-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Cyclic AMP Receptor Protein Regulates Quorum Sensing and Global Gene Expression in Yersinia pestis during Planktonic Growth and Growth in Biofilms.
Mbio, 10, 2019
2QCS
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BU of 2qcs by Molmil
A complex structure between the Catalytic and Regulatory subunit of Protein Kinase A that represents the inhibited state
分子名称: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Kim, C, Cheng, C.Y, Saldanha, A.S, Taylor, S.S.
登録日2007-06-19
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation.
Cell(Cambridge,Mass.), 130, 2007
6EO1
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BU of 6eo1 by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1 (PCO-refined)
分子名称: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
著者Kowal, J, Biyani, N, Chami, M, Scherer, S, Rzepiela, A, Baumgartner, P, Upadhyay, V, Nimigean, C, Stahlberg, H.
登録日2017-10-08
公開日2017-12-27
最終更新日2024-05-15
実験手法ELECTRON CRYSTALLOGRAPHY (4.5 Å)
主引用文献High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer.
Structure, 26, 2018
2QVS
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BU of 2qvs by Molmil
Crystal Structure of Type IIa Holoenzyme of cAMP-dependent Protein Kinase
分子名称: cAMP-dependent protein kinase type II-alpha regulatory subunit, cAMP-dependent protein kinase, alpha-catalytic subunit
著者Wu, J, Brown, S.H.J, von Daake, S, Taylor, S.S.
登録日2007-08-08
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity.
Science, 318, 2007
6V1X
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BU of 6v1x by Molmil
Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Tetramer
分子名称: (2S)-1-(nonanoyloxy)-3-(phosphonooxy)propan-2-yl tetradecanoate, (3beta,5beta,14beta,17alpha)-cholestan-3-ol, Potassium channel KAT1
著者Clark, M.D, Contreras, G.F, Shen, R, Perozo, E.
登録日2019-11-21
公開日2020-06-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Electromechanical coupling in the hyperpolarization-activated K + channel KAT1.
Nature, 583, 2020
6UQF
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Human HCN1 channel in a hyperpolarized conformation
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MERCURY (II) ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者Lee, C.-H, MacKinnon, R.
登録日2019-10-19
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
Cell, 179, 2019
6UQG
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BU of 6uqg by Molmil
Human HCN1 channel Y289D mutant
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者Lee, C.-H, MacKinnon, R.
登録日2019-10-19
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
Cell, 179, 2019
6V1Y
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BU of 6v1y by Molmil
Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Octamer
分子名称: (2S)-1-(nonanoyloxy)-3-(phosphonooxy)propan-2-yl tetradecanoate, (3beta,5beta,14beta,17alpha)-cholestan-3-ol, Potassium channel KAT1
著者Clark, M.D, Contreras, G.F, Shen, R, Perozo, E.
登録日2019-11-21
公開日2020-06-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Electromechanical coupling in the hyperpolarization-activated K + channel KAT1.
Nature, 583, 2020
6VXZ
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SthK P300A cyclic nucleotide-gated potassium channel in the closed state, in complex with cAMP
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK
著者Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M.
登録日2020-02-25
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel.
Nat Commun, 11, 2020
6VY0
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SthK P300A cyclic nucleotide-gated potassium channel in a putative active state, in complex with cAMP
分子名称: SthK
著者Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M.
登録日2020-02-25
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.68 Å)
主引用文献Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel.
Nat Commun, 11, 2020
2WC2
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Nmr structure of catabolite activator protein in the unliganded state
分子名称: CATABOLITE GENE ACTIVATOR
著者Popovych, N, Tzeng, S.R, Kalodimos, C.G.
登録日2009-03-06
公開日2009-04-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Camp-Mediated Allosteric Control of the Catabolite Activator Protein.
Proc.Natl.Acad.Sci.USA, 106, 2009

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