4QHD
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![BU of 4qhd by Molmil](/molmil-images/mine/4qhd) | Crystal structure of apo human APE1 | Descriptor: | 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase | Authors: | He, H, Chen, Q, Georgiadis, M.M. | Deposit date: | 2014-05-28 | Release date: | 2014-11-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I. Biochemistry, 53, 2014
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4QH9
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![BU of 4qh9 by Molmil](/molmil-images/mine/4qh9) | Crystal structure of Mn2+ bound human APE1 | Descriptor: | 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MANGANESE (II) ION | Authors: | Chen, Q, He, H, Georgiadis, M.M. | Deposit date: | 2014-05-27 | Release date: | 2014-11-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.175 Å) | Cite: | High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I. Biochemistry, 53, 2014
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5GSU
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![BU of 5gsu by Molmil](/molmil-images/mine/5gsu) | Crystal structure of nucleosome core particle consisting of human testis-specific histone variants, Th2A and Th2B | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-A, ... | Authors: | Kumarevel, T, Sivaraman, P. | Deposit date: | 2016-08-17 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b Biophys. Chem., 221, 2017
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3OSF
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![BU of 3osf by Molmil](/molmil-images/mine/3osf) | The structure of protozoan parasite Trichomonas vaginalis Myb2 in complex with MRE-2f-13 DNA | Descriptor: | 5'-D(*CP*AP*AP*GP*AP*CP*GP*AP*TP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*AP*TP*CP*GP*TP*CP*TP*TP*G)-3', ISOPROPYL ALCOHOL, ... | Authors: | Jiang, I, Tsai, C.K, Chen, S.C, Wang, S.H, Amiraslanov, I, Chang, C.F, Wu, W.J, Tai, J.H, Liaw, Y.C, Huang, T.H. | Deposit date: | 2010-09-09 | Release date: | 2011-08-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.032 Å) | Cite: | Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 39, 2011
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4QHE
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![BU of 4qhe by Molmil](/molmil-images/mine/4qhe) | Crystal structure of Mg2+ bound human APE1 | Descriptor: | 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION | Authors: | He, H, Chen, Q, Georgiadis, M.M. | Deposit date: | 2014-05-28 | Release date: | 2014-11-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I. Biochemistry, 53, 2014
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3OSG
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![BU of 3osg by Molmil](/molmil-images/mine/3osg) | The structure of protozoan parasite Trichomonas vaginalis Myb2 in complex with MRE-1-12 DNA | Descriptor: | 5'-D(*AP*AP*AP*TP*AP*TP*CP*GP*TP*TP*AP*T)-3', 5'-D(*AP*TP*AP*AP*CP*GP*AP*TP*AP*TP*TP*T)-3', MYB21 | Authors: | Jiang, I, Tsai, C.K, Chen, S.C, Wang, S.H, Amiraslanov, I, Chang, C.F, Wu, W.J, Tai, J.H, Liaw, Y.C, Huang, T.H. | Deposit date: | 2010-09-09 | Release date: | 2011-08-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 39, 2011
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6KW3
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![BU of 6kw3 by Molmil](/molmil-images/mine/6kw3) | The ClassA RSC-Nucleosome Complex | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | Deposit date: | 2019-09-05 | Release date: | 2019-11-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7.13 Å) | Cite: | Structure of the RSC complex bound to the nucleosome. Science, 366, 2019
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7K78
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![BU of 7k78 by Molmil](/molmil-images/mine/7k78) | antibody and nucleosome complex | Descriptor: | Cse4, DNA (136-MER), Histone H2A.1, ... | Authors: | Ruifang, G, Yawen, B. | Deposit date: | 2020-09-22 | Release date: | 2021-03-31 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation. Nat Commun, 12, 2021
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1AE3
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![BU of 1ae3 by Molmil](/molmil-images/mine/1ae3) | MUTANT R82C OF GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN) | Descriptor: | GENE V PROTEIN | Authors: | Su, S, Gao, Y.-G, Zhang, H, Terwilliger, T.C, Wang, A.H.-J. | Deposit date: | 1997-03-04 | Release date: | 1997-09-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography. Protein Sci., 6, 1997
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8A5R
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![BU of 8a5r by Molmil](/molmil-images/mine/8a5r) | Crystal structure of light-activated DNA-binding protein EL222 from Erythrobacter litoralis crystallized and measured in dark. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | Authors: | Koval, T, Chaudhari, A, Fuertes, G, Andersson, I, Dohnalek, J. | Deposit date: | 2022-06-15 | Release date: | 2023-07-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | EL222 from Erythrobacter litoralis. To Be Published
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8A5S
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![BU of 8a5s by Molmil](/molmil-images/mine/8a5s) | Crystal structure of light-activated DNA-binding protein EL222 from Erythrobacter litoralis crystallized in dark, measured illuminated. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | Authors: | Koval, T, Chaudhari, A, Fuertes, G, Andersson, I, Dohnalek, J. | Deposit date: | 2022-06-15 | Release date: | 2023-07-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | EL222 from Erythrobacter litoralis. To Be Published
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7UY5
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![BU of 7uy5 by Molmil](/molmil-images/mine/7uy5) | Tetrahymena telomerase with CST | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-05-06 | Release date: | 2022-07-13 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
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7UY6
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![BU of 7uy6 by Molmil](/molmil-images/mine/7uy6) | Tetrahymena telomerase at 2.9 Angstrom resolution | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-05-06 | Release date: | 2022-07-13 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
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7ET4
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![BU of 7et4 by Molmil](/molmil-images/mine/7et4) | Crystal structure of Arabidopsis TEM1 AP2 domain | Descriptor: | AP2/ERF and B3 domain-containing transcription repressor TEM1, DNA (12-mer) | Authors: | Hu, H, Du, J. | Deposit date: | 2021-05-12 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis. Proc.Natl.Acad.Sci.USA, 118, 2021
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3UGO
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![BU of 3ugo by Molmil](/molmil-images/mine/3ugo) | |
3QSB
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![BU of 3qsb by Molmil](/molmil-images/mine/3qsb) | Structure of E. coli polIIIbeta with (Z)-5-(1-((4'-Fluorobiphenyl-4-yl)methoxyimino)butyl)-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile | Descriptor: | (1R,5R)-5-{(1Z)-N-[(4'-fluorobiphenyl-4-yl)methoxy]butanimidoyl}-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile, DNA polymerase III subunit beta | Authors: | Wijffels, G, Johnson, W.M, Oakley, A.J, Turner, K, Epa, V.C, Briscoe, S.J, Polley, M, Liepa, A.J, Hofmann, A, Buchardt, J, Christensen, C, Prosselkov, P, Dalrymple, B.P, Alewood, P.F, Jennings, P.A, Dixon, N.E, Winkler, D.A. | Deposit date: | 2011-02-20 | Release date: | 2011-06-08 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Binding inhibitors of the bacterial sliding clamp by design J.Med.Chem., 54, 2011
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1AE2
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![BU of 1ae2 by Molmil](/molmil-images/mine/1ae2) | MUTANT L32R OF GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN) | Descriptor: | GENE V PROTEIN | Authors: | Su, S, Gao, Y.-G, Zhang, H, Terwilliger, T.C, Wang, A.H.-J. | Deposit date: | 1997-03-04 | Release date: | 1997-09-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography. Protein Sci., 6, 1997
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5GT3
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![BU of 5gt3 by Molmil](/molmil-images/mine/5gt3) | Crystal structure of nucleosome particle in the presence of human testis-specific histone variant, hTh2b | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-D, ... | Authors: | Kumarevel, T, Sivaraman, P. | Deposit date: | 2016-08-18 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b Biophys. Chem., 221, 2017
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6C2S
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![BU of 6c2s by Molmil](/molmil-images/mine/6c2s) | Transcriptional repressor, CouR, bound to a 23-mer DNA duplex | Descriptor: | 23-mer, Transcriptional regulator, MarR family | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2018-01-08 | Release date: | 2018-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural basis of transcriptional regulation by CouR, a repressor of coumarate catabolism, inRhodopseudomonas palustris. J. Biol. Chem., 293, 2018
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5C5J
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![BU of 5c5j by Molmil](/molmil-images/mine/5c5j) | Poymerase Nucleotide complex | Descriptor: | 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase IV, ... | Authors: | Nair, D.T, Kottur, J. | Deposit date: | 2015-06-20 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Reactive Oxygen Species Play an Important Role in the Bactericidal Activity of Quinolone Antibiotics Angew.Chem.Int.Ed.Engl., 55, 2016
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4A12
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![BU of 4a12 by Molmil](/molmil-images/mine/4a12) | Structure of the global transcription regulator FapR from Staphylococcus aureus in complex with DNA operator | Descriptor: | FAPR PROMOTER, TRANSCRIPTION FACTOR FAPR | Authors: | Albanesi, D, Guerin, M.E, Buschiazzo, A, de Mendoza, D, Alzari, P.M. | Deposit date: | 2011-09-13 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus Aureus. Plos Pathog., 9, 2013
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6ZWT
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![BU of 6zwt by Molmil](/molmil-images/mine/6zwt) | Crystal structure of DNA-binding domain of OmpR of two-component system of Acinetobacter baumannii | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ... | Authors: | Narwal, M, Lucchini, V, Trebosc, V, Gartenmann, S, Pieren, M, Kemmer, C, Kammerer, R.A. | Deposit date: | 2020-07-28 | Release date: | 2021-08-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis. Virulence, 13, 2022
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2BKE
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![BU of 2bke by Molmil](/molmil-images/mine/2bke) | Conformational Flexibility Revealed by the Crystal Structure of a Crenarchaeal RadA | Descriptor: | CHLORIDE ION, DNA REPAIR AND RECOMBINATION PROTEIN RADA | Authors: | Ariza, A, Richard, D.L, White, M.F, Bond, C.S. | Deposit date: | 2005-02-15 | Release date: | 2005-03-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Conformational Flexibility Revealed by the Crystal Structure of a Crenarchaeal Rada Nucleic Acids Res., 33, 2005
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7TC3
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![BU of 7tc3 by Molmil](/molmil-images/mine/7tc3) | Human APE1 in the apo form | Descriptor: | 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial | Authors: | Pidugu, L.S, Pozharski, E, Drohat, A.C. | Deposit date: | 2021-12-22 | Release date: | 2022-12-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.252 Å) | Cite: | Characterizing inhibitors of human AP endonuclease 1. Plos One, 18, 2023
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7TC2
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![BU of 7tc2 by Molmil](/molmil-images/mine/7tc2) | Human APE1 in complex with 5-nitroindole-2-carboxylic acid | Descriptor: | 1,2-ETHANEDIOL, 5-nitro-1H-indole-2-carboxylic acid, DI(HYDROXYETHYL)ETHER, ... | Authors: | Pidugu, L.S, Pozharski, E, Drohat, A.C. | Deposit date: | 2021-12-22 | Release date: | 2022-12-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Characterizing inhibitors of human AP endonuclease 1. Plos One, 18, 2023
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