PDB: 619 件ウェブページステータス検索Chemie searchBIRD

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2FU7	Zinc-beta-lactamase L1 from stenotrophomonas maltophilia (Cu-substituted form) 分子名称: 1,10-PHENANTHROLINE, COPPER (II) ION, GLYCEROL, ... 著者 Nauton, L, Garau, G, Kahn, R, Dideberg, O. 登録日 2006-01-26 公開日 2007-01-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
2FU8	Zinc-beta-lactamase L1 from stenotrophomonas maltophilia (d-captopril complex) 分子名称: 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID, GLYCEROL, Metallo-beta-lactamase L1, ... 著者 Nauton, L, Garau, G, Kahn, R, Dideberg, O. 登録日 2006-01-26 公開日 2007-01-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
5HIQ	Crystal Structure of PQS Response Protein PqsE in Complex with 2-(1H-pyrrol-1-yl)benzoic acid 分子名称: 2-pyrrol-1-ylbenzoic acid, FE (III) ION, PqsE 著者 Witzgall, F, Blankenfeldt, W. 登録日 2016-01-12 公開日 2016-04-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds. Acs Chem.Biol., 11, 2016
5HIS	Crystal Structure of PQS Response Protein PqsE in Complex with 3-methylthiophene-2-carboxylic acid 分子名称: 3-methylthiophene-2-carboxylic acid, FE (III) ION, PqsE 著者 Witzgall, F, Blankenfeldt, W. 登録日 2016-01-12 公開日 2016-04-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds. Acs Chem.Biol., 11, 2016
2FU6	Zinc-beta-lactamase l1 from stenotrophomonas maltophilia (apo form) 分子名称: GLYCEROL, Metallo-beta-lactamase L1, SULFATE ION 著者 Nauton, L, Garau, G, Kahn, R, Dideberg, O. 登録日 2006-01-26 公開日 2007-01-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of the zinc-beta-lactamase L1 from stenotrophomonas maltophilia (apo form) To be Published
2GFK	Crystal structure of the zinc-beta-lactamase l1 from stenotrophomonas maltophilia (inhibitor 2) 分子名称: 2,5-DIPHENYLFURAN-3,4-DICARBOXYLIC ACID, DI(HYDROXYETHYL)ETHER, Metallo-beta-lactamase L1, ... 著者 Nauton, L, Garau, G, Kahn, R, Dideberg, O. 登録日 2006-03-22 公開日 2007-03-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
5HH5	Crystal structure of B3 metallo-beta-lactamase L1 complexed with a phosphonate-based inhibitor 分子名称: 6-(phosphonomethyl)pyridine-2-carboxylic acid, GLYCEROL, Metallo-beta-lactamase L1, ... 著者 Hinchliffe, P, Spencer, J. 登録日 2016-01-09 公開日 2017-01-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and Kinetic Studies of the Potent Inhibition of Metallo-beta-lactamases by 6-Phosphonomethylpyridine-2-carboxylates. Biochemistry, 57, 2018
2GCU	X-Ray Structure of Gene Product from Arabidopsis Thaliana At1g53580 分子名称: 1,2-ETHANEDIOL, FE (II) ION, Putative hydroxyacylglutathione hydrolase 3, ... 著者 McCoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-03-14 公開日 2006-04-18 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.477 Å) 主引用文献 Structure of an ETHE1-like protein from Arabidopsis thaliana. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2GFJ	Crystal structure of the zinc-beta-lactamase L1 from stenotrophomonas maltophilia (inhibitor 1) 分子名称: 1,3-DIPHENYL-1H-PYRAZOLE-4,5-DICARBOXYLIC ACID, Metallo-beta-lactamase L1, SULFATE ION, ... 著者 Nauton, L, Garau, G, Kahn, R, Dideberg, O. 登録日 2006-03-22 公開日 2007-03-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
2H6A	Crystal structure of the zinc-beta-lactamase L1 from Stenotrophomonas maltophilia (mono zinc form) 分子名称: Metallo-beta-lactamase L1, SULFATE ION, ZINC ION 著者 Nauton, L, Garau, G, Kahn, R, Dideberg, O. 登録日 2006-05-31 公開日 2007-04-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
2GMN	Crystal structure of BJP-1, a subclass B3 metallo-beta-lactamase of Bradyrhizobium japonicum 分子名称: Metallo-beta-lactamase, ZINC ION 著者 Calderone, V, Benvenuti, M, Stoczko, M, Docquier, J.D, Rossolini, G.M, Mangani, S. 登録日 2006-04-07 公開日 2007-04-24 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Postgenomic scan of metallo-beta-lactamase homologues in rhizobacteria: identification and characterization of BJP-1, a subclass B3 ortholog from Bradyrhizobium japonicum. Antimicrob.Agents Chemother., 50, 2006
2GKL	Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate 分子名称: Beta-lactamase, GLYCEROL, PYRIDINE-2,4-DICARBOXYLIC ACID, ... 著者 Garau, G, Dideberg, O. 登録日 2006-04-03 公開日 2007-03-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Competitive Inhibitors of the CphA Metallo-{beta}-Lactamase from Aeromonas hydrophila Antimicrob.Agents Chemother., 51, 2007
5IQK	Rm3 metallo-beta-lactamase 分子名称: ZINC ION, beta-lactamase Rm3 著者 Salimraj, R, Spencer, J. 登録日 2016-03-10 公開日 2016-03-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and Biochemical Characterization of Rm3, a Subclass B3 Metallo-beta-Lactamase Identified from a Functional Metagenomic Study. Antimicrob.Agents Chemother., 60, 2016
2HB9	Crystal Structure of the Zinc-Beta-Lactamase L1 from Stenotrophomonas Maltophilia (Inhibitor 3) 分子名称: 4-AMINO-5-(2-METHYLPHENYL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOLE-3-THIONE, Metallo-beta-lactamase L1, SULFATE ION, ... 著者 Nauton, L, Garau, G, Kahn, R, Dideberg, O. 登録日 2006-06-14 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
5JMX	Crystal Structure of BcII metallo-beta-lactamase in complex with DZ-305 分子名称: (2Z)-3-(4-fluorophenyl)-2-sulfanylprop-2-enoic acid, GLYCEROL, Metallo-beta-lactamase type 2, ... 著者 Stepanovs, D, McDonough, M.A, Schofield, C.J, Zhang, D, Brem, J. 登録日 2016-04-29 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases. Bioorg. Med. Chem., 26, 2018
5JQJ	Directed evolutionary changes in MBL super family - NDM-1 Round 10 crystal-1 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Metallo-beta-lactamase type 2, ... 著者 Hong, N.-S, Jackson, C.J, Carr, P.D. 登録日 2016-05-05 公開日 2017-05-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Enzyme evolvability is contingent on the initial sequence background To Be Published
5K4M	Directed evolutionary changes in MBL super family - NDM-1 Round 10 crystal-3 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Metallo-beta-lactamase type 2, ... 著者 Hong, N.-S, Jackson, C.J, Carr, P.D. 登録日 2016-05-20 公開日 2017-04-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Enzyme evolvability is contingent on the initial sequence background To Be Published
5K48	VIM-2 Metallo Beta Lactamase in complex with 3-(mercaptomethyl)-[1,1'-biphenyl]-4-carboxylic acid 分子名称: 4-phenyl-2-(sulfanylmethyl)benzoic acid, Beta-lactamase VIM-2, FORMIC ACID, ... 著者 Zollman, D, McDonough, M, Brem, J, Schofield, C. 登録日 2016-05-20 公開日 2017-06-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.744 Å) 主引用文献 In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-beta-lactamase Inhibitors. J. Med. Chem., 61, 2018
4PVO	Crystal Structure of VIM-2 metallo-beta-lactamase in complex with ML302 and ML302F 分子名称: (2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid, Beta-lactamase class B VIM-2, DIMETHYL SULFOXIDE, ... 著者 Aik, W.S, Brem, J, McDonough, M.A, Schofield, C.J. 登録日 2014-03-18 公開日 2014-11-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Rhodanine hydrolysis leads to potent thioenolate mediated metallo-beta-lactamase inhibition. Nat.Chem., 6, 2014
6D1E	Crystal structure of NDM-1 complexed with compound 7 分子名称: ACETATE ION, Metallo-beta-lactamase type 2, ZINC ION, ... 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
6D1K	Crystal structure of NDM-1 complexed with compound 14 分子名称: ACETATE ION, Metallo-beta-lactamase type 2, ZINC ION, ... 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
6D1F	Crystal structure of NDM-1 complexed with compound 8 分子名称: ACETATE ION, Metallo-beta-lactamase type 2, ZINC ION, ... 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
6D1C	Crystal structure of NDM-1 complexed with compound 3 分子名称: ACETATE ION, Metallo-beta-lactamase type 2, ZINC ION, ... 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
6D1G	Crystal structure of NDM-1 complexed with compound 9 分子名称: ACETATE ION, Metallo-beta-lactamase type 2, ZINC ION, ... 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
6D1J	Crystal structure of NDM-1 complexed with compound 13 分子名称: ACETATE ION, Metallo-beta-lactamase type 2, ZINC ION, ... 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019

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