8PSM
| Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the malonyl/palmitoyl transferase domain (FASx sample) | 分子名称: | 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PSP
| Asymmetric unit of the yeast fatty acid synthase in rotated state with ACP at the acetyl transferase domain (FASx sample) | 分子名称: | 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PSG
| Asymmetric unit of the yeast fatty acid synthase in the semi non-rotated state with ACP at the acetyl transferase domain (FASx sample) | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PS8
| Asymmetric unit of the yeast fatty acid synthase in the semi non-rotated state with ACP at the enoyl reductase domain (FASam sample) | 分子名称: | Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-26 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PS2
| Asymmetric unit of the yeast fatty acid synthase with ACP at the enoyl reductase domain (FASam sample) | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PSJ
| Asymmetric unit of the yeast fatty acid synthase in the semi rotated state with ACP at the acetyl transferase domain (FASx sample) | 分子名称: | 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PS9
| Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the ketosynthase domain (FASam sample) | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PSF
| Asymmetric unit of the yeast fatty acid synthase in non-rotated state with ACP at the acetyl transferase domain (FASx sample) | 分子名称: | 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8PSL
| Asymmetric unit of the yeast fatty acid synthase in the semi non-rotated state with ACP at the ketosynthase domain (FASx sample) | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | 登録日 | 2023-07-13 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell, 186, 2023
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8SMS
| Crosslinked Crystal Structure of Type II Fatty Acid Synthase, FabB, and cerulenin crosslinker-crypto Acyl Carrier Protein, AcpP | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(2R)-2-hydroxy-4-oxododecanamido]ethyl}-beta-alaninamide | 著者 | Jiang, Z, Chen, A, Chen, J, Sekhon, A, Louie, G.V, Noel, J.P, La Clair, J.J, Burkart, M.D. | 登録日 | 2023-04-26 | 公開日 | 2023-09-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Masked cerulenin enables a dual-site selective protein crosslink. Chem Sci, 14, 2023
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8EE0
| KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody fragment 1B2 | 分子名称: | 1B2 antibody heavy chain, 1B2 antibody light chain, 6-deoxyerythronolide B synthase | 著者 | Cogan, D.P, Brodsky, K.L, Guzman, K.M, Mathews, I.I, Khosla, C. | 登録日 | 2022-09-06 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase. Biochemistry, 62, 2023
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8EE1
| KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody fragment AA5 | 分子名称: | 6-deoxyerythronolide B synthase, AA5 antibody heavy chain, AA5 antibody light chain | 著者 | Cogan, D.P, Brodsky, K.L, Guzman, K.M, Mathews, I.I, Khosla, C. | 登録日 | 2022-09-06 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase. Biochemistry, 62, 2023
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8IN9
| The structure of the GfsA KSQ-AT didomain in complex with the GfsA ACP domain | 分子名称: | N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, Polyketide synthase | 著者 | Chisuga, T, Murakami, S, Miyanaga, A, Kudo, F, Eguchi, T. | 登録日 | 2023-03-09 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-28 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase. Acs Chem.Biol., 18, 2023
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8CJH
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8G4U
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7WVZ
| CalA3_modular PKS_KS-AT-DH-KR | 分子名称: | Beta-ketoacyl-acyl-carrier-protein synthase I | 著者 | Wang, J, Wang, Z. | 登録日 | 2022-02-12 | 公開日 | 2023-02-22 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | C-N bond formation by a polyketide synthase. Nat Commun, 14, 2023
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8I4Z
| CalA3 with hydrolysis product | 分子名称: | 11-oxidanylidene-11-(1~{H}-pyrrol-2-yl)undecanoic acid, Beta-ketoacyl-acyl-carrier-protein synthase I | 著者 | Wang, J, Wang, Z. | 登録日 | 2023-01-21 | 公開日 | 2023-02-22 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | C-N bond formation by a polyketide synthase. Nat Commun, 14, 2023
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8I4Y
| CalA3 complex structure with amidation product | 分子名称: | 11-oxidanylidene-11-(1~{H}-pyrrol-2-yl)undecanoic acid, 3-HYDROXYANTHRANILIC ACID, Beta-ketoacyl-acyl-carrier-protein synthase I | 著者 | Wang, J, Wang, Z. | 登録日 | 2023-01-21 | 公開日 | 2023-02-22 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | 主引用文献 | C-N bond formation by a polyketide synthase. Nat Commun, 14, 2023
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8CV1
| ACP1-KS-AT domains of mycobacterial Pks13 | 分子名称: | Polyketide synthase PKS13, UNKNOWN LIGAND | 著者 | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | 登録日 | 2022-05-17 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
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8CUZ
| KS-AT domains of mycobacterial Pks13 with inward AT conformation | 分子名称: | Polyketide synthase PKS13, UNKNOWN LIGAND | 著者 | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | 登録日 | 2022-05-17 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
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8CUY
| ACP1-KS-AT domains of mycobacterial Pks13 | 分子名称: | 4'-PHOSPHOPANTETHEINE, Polyketide synthase PKS13, UNKNOWN LIGAND | 著者 | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | 登録日 | 2022-05-17 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
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8CV0
| KS-AT domains of mycobacterial Pks13 with outward AT conformation | 分子名称: | Polyketide synthase PKS13, UNKNOWN LIGAND | 著者 | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | 登録日 | 2022-05-17 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
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7TUI
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7UK4
| KS-AT di-domain of mycobacterial Pks13 with endogenous KS ligand bound | 分子名称: | Polyketide synthase PKS13, UNKNOWN LIGAND | 著者 | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | 登録日 | 2022-03-31 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (1.94 Å) | 主引用文献 | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
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7SZ9
| Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and C16:1-crypto Acyl Carrier Protein, AcpP | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, N~3~-{(2R)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-(2-{[(9Z)-hexadec-9-enoyl]amino}ethyl)-beta-alaninamide, ... | 著者 | Mindrebo, J.T, Chen, A, Noel, J.P, Burkart, M.D. | 登録日 | 2021-11-26 | 公開日 | 2022-11-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanism-based cross-linking probes capture the Escherichia coli ketosynthase FabB in conformationally distinct catalytic states. Acta Crystallogr D Struct Biol, 78, 2022
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