8CJH
Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin
Summary for 8CJH
| Entry DOI | 10.2210/pdb8cjh/pdb |
| Descriptor | Colibactin hybrid non-ribosomal peptide synthetase/type I polyketide synthase ClbK (1 entity in total) |
| Functional Keywords | polyketide synthase, ketosynthase domain, acyltransferase domain, acyl carrier protein domain, biosynthetic protein |
| Biological source | Escherichia coli |
| Total number of polymer chains | 6 |
| Total formula weight | 512582.39 |
| Authors | Bonhomme, S.,Dessen, A.,Macheboeuf, P. (deposition date: 2023-02-13, release date: 2023-04-26, Last modification date: 2023-06-14) |
| Primary citation | Bonhomme, S.,Contreras-Martel, C.,Dessen, A.,Macheboeuf, P. Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin. Structure, 31:700-, 2023 Cited by PubMed: 37059096DOI: 10.1016/j.str.2023.03.012 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.982 Å) |
Structure validation
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