2KF3
| |
1X1Y
| |
3VRE
| The crystal structure of hemoglobin from woolly mammoth in the deoxy form | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2012-04-09 | Release date: | 2012-11-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of haemoglobin from woolly mammoth in liganded and unliganded states. Acta Crystallogr.,Sect.D, 68, 2012
|
|
3VRG
| The crystal structure of hemoglobin from woolly mammoth in the met form | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2012-04-09 | Release date: | 2012-11-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of haemoglobin from woolly mammoth in liganded and unliganded states. Acta Crystallogr.,Sect.D, 68, 2012
|
|
1X1U
| |
2QGC
| |
3VQH
| Bromine SAD partially resolves multiple binding modes for PKA inhibitor H-89 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, cAMP-dependent protein kinase catalytic subunit alpha, ... | Authors: | Pflug, A, Johnson, K.A, Engh, R.A. | Deposit date: | 2012-03-23 | Release date: | 2012-08-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Anomalous dispersion analysis of inhibitor flexibility: a case study of the kinase inhibitor H-89 Acta Crystallogr.,Sect.F, 68, 2012
|
|
1X1X
| |
2GVY
| |
4B1Z
| Structure of the Phactr1 RPEL domain bound to G-actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. | Deposit date: | 2012-07-12 | Release date: | 2012-11-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
|
|
3D15
| Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-(3-chloro-phenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)- ethyl]-thiazol-2-yl}-urea [SNS-314] | Descriptor: | 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea, serine/threonine kinase 6 | Authors: | Elling, R.A, Bui, M, Allen, D.A, Oslob, J.D, Romanowski, M.J. | Deposit date: | 2008-05-04 | Release date: | 2009-05-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of a potent and selective aurora kinase inhibitor. Bioorg.Med.Chem.Lett., 18, 2008
|
|
4B1T
| Structure of the factor Xa-like trypsin variant triple-Ala (TA) in complex with eglin C | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... | Authors: | Menzel, A, Neumann, P, Stubbs, M.T. | Deposit date: | 2012-07-12 | Release date: | 2012-08-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Thermodynamic signatures in macromolecular interactions involving conformational flexibility. Biol.Chem., 395, 2014
|
|
1RNB
| |
1X1W
| |
3D2I
| Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylamino)-ethyl]-thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea | Descriptor: | 1-(5-{2-[(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea, serine/threonine kinase 6 | Authors: | Oslob, J.D, Yu, C, Romanowski, M.J. | Deposit date: | 2008-05-08 | Release date: | 2009-05-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Discovery of Aurora-A-selective inhibitors To be Published
|
|
4AS1
| Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole AN2679 in the editing conformation | Descriptor: | LEUCINE--TRNA LIGASE, MAGNESIUM ION, TRNA-LEU5 (UAA ISOACEPTOR) | Authors: | Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. | Deposit date: | 2012-04-27 | Release date: | 2012-06-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase Nat.Struct.Mol.Biol., 19, 2012
|
|
2GTP
| Crystal structure of the heterodimeric complex of human RGS1 and activated Gi alpha 1 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ... | Authors: | Soundararajan, M, Turnbull, A.P, Ugochukwu, E, Gorrec, F, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2006-04-28 | Release date: | 2006-05-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
4B1V
| Structure of the Phactr1 RPEL-N domain bound to G-actin | Descriptor: | 1,2-ETHANEDIOL, ACTIN, ALPHA SKELETAL MUSCLE, ... | Authors: | Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. | Deposit date: | 2012-07-12 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
|
|
1SBN
| |
2JWZ
| Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins | Descriptor: | Ubiquitin | Authors: | Haririnia, A, Verma, R, Purohit, N, Twarog, M, Deshaies, R, Bolon, D, Fushman, D. | Deposit date: | 2007-10-31 | Release date: | 2008-01-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins. J.Mol.Biol., 375, 2008
|
|
2R55
| Human StAR-related lipid transfer protein 5 | Descriptor: | StAR-related lipid transfer protein 5 | Authors: | Lehtio, L, Busam, R.D, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Herman, M.D, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Sagemark, J, Sundstrom, M, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Persson, C, Structural Genomics Consortium (SGC) | Deposit date: | 2007-09-03 | Release date: | 2007-09-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Comparative structural analysis of lipid binding START domains. Plos One, 6, 2011
|
|
2REL
| SOLUTION STRUCTURE OF R-ELAFIN, A SPECIFIC INHIBITOR OF ELASTASE, NMR, 11 STRUCTURES | Descriptor: | R-ELAFIN | Authors: | Francart, C, Dauchez, M, Alix, A.J.P, Lippens, G. | Deposit date: | 1997-04-01 | Release date: | 1997-07-07 | Last modified: | 2024-10-16 | Method: | SOLUTION NMR | Cite: | Solution structure of R-elafin, a specific inhibitor of elastase. J.Mol.Biol., 268, 1997
|
|
1ZO1
| IF2, IF1, and tRNA fitted to cryo-EM data OF E. COLI 70S initiation complex | Descriptor: | P/I-site tRNA, translation Initiation Factor 1, translation initiation factor 2 | Authors: | Allen, G.S, Zavialov, A, Gursky, R, Ehrenberg, M, Frank, J. | Deposit date: | 2005-05-12 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (13.8 Å) | Cite: | The Cryo-EM Structure of a Translation Initiation Complex from Escherichia coli. Cell(Cambridge,Mass.), 121, 2005
|
|
1ZO3
| The P-site and P/E-site tRNA structures fitted to P/I site codon. | Descriptor: | tRNA | Authors: | Allen, G.S, Zavialov, A, Gursky, R, Ehrenberg, M, Frank, J. | Deposit date: | 2005-05-12 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (13.8 Å) | Cite: | The Cryo-EM Structure of a Translation Initiation Complex from Escherichia coli. Cell(Cambridge,Mass.), 121, 2005
|
|
1YVE
| ACETOHYDROXY ACID ISOMEROREDUCTASE COMPLEXED WITH NADPH, MAGNESIUM AND INHIBITOR IPOHA (N-HYDROXY-N-ISOPROPYLOXAMATE) | Descriptor: | ACETOHYDROXY ACID ISOMEROREDUCTASE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Biou, V, Dumas, R, Cohen-Addad, C, Douce, R, Job, D, Pebay-Peyroula, E. | Deposit date: | 1996-10-11 | Release date: | 1997-09-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The crystal structure of plant acetohydroxy acid isomeroreductase complexed with NADPH, two magnesium ions and a herbicidal transition state analog determined at 1.65 A resolution. EMBO J., 16, 1997
|
|