1WJX
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![BU of 1wjx by Molmil](/molmil-images/mine/1wjx) | Crystal sturucture of TT0801 from Thermus thermophilus | Descriptor: | POTASSIUM ION, SsrA-binding protein | Authors: | Bessho, Y, Shibata, R, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-29 | Release date: | 2004-11-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for functional mimicry of long-variable-arm tRNA by transfer-messenger RNA. Proc.Natl.Acad.Sci.Usa, 104, 2007
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4BL1
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![BU of 4bl1 by Molmil](/molmil-images/mine/4bl1) | Crystal structure of unphosphorylated Maternal Embryonic Leucine zipper Kinase (MELK) in complex with AMP-PNP | Descriptor: | MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Canevari, G, Re-Depaolini, S, Cucchi, U, Forte, B, Carpinelli, P, Bertrand, J.A. | Deposit date: | 2013-04-30 | Release date: | 2013-05-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Unphosphorylated Maternal Embryonic Leucine Zipper Kinase To be Published
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7C07
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![BU of 7c07 by Molmil](/molmil-images/mine/7c07) | Crystal structure of yeast U2AF1 complex bound to 5'-AAGGU RNA. | Descriptor: | RNA (5'-R(*U*AP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ... | Authors: | Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. | Deposit date: | 2020-04-30 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1. Nat Commun, 11, 2020
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4RU2
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![BU of 4ru2 by Molmil](/molmil-images/mine/4ru2) | |
6YLE
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![BU of 6yle by Molmil](/molmil-images/mine/6yle) | |
6SCX
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![BU of 6scx by Molmil](/molmil-images/mine/6scx) | Crystal structure of the catalytic domain of human NUDT12 in complex with 7-methyl-guanosine-5'-triphosphate | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CADMIUM ION, Peroxisomal NADH pyrophosphatase NUDT12 | Authors: | McCarthy, A.A, Chen, K.M, Wu, H, Li, L, Homolka, D, Gos, P, Fleury-Olela, F, Pillai, R.S. | Deposit date: | 2019-07-25 | Release date: | 2020-01-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs. Cell Rep, 29, 2019
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5A48
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![BU of 5a48 by Molmil](/molmil-images/mine/5a48) | |
5A49
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![BU of 5a49 by Molmil](/molmil-images/mine/5a49) | |
3LRK
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![BU of 3lrk by Molmil](/molmil-images/mine/3lrk) | Structure of alfa-galactosidase (MEL1) from Saccharomyces cerevisiae | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fernandez-Leiro, R, Pereira-Rodriguez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. | Deposit date: | 2010-02-11 | Release date: | 2010-06-30 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural analysis of Saccharomyces cerevisiae alpha-galactosidase and its complexes with natural substrates reveals new insights into substrate specificity of GH27 glycosidases. J.Biol.Chem., 285, 2010
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3LRM
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![BU of 3lrm by Molmil](/molmil-images/mine/3lrm) | Structure of alfa-galactosidase from Saccharomyces cerevisiae with raffinose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fernandez-Leiro, R, Pereira-Rodriguez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. | Deposit date: | 2010-02-11 | Release date: | 2010-06-30 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural analysis of Saccharomyces cerevisiae alpha-galactosidase and its complexes with natural substrates reveals new insights into substrate specificity of GH27 glycosidases. J.Biol.Chem., 285, 2010
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5LQT
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![BU of 5lqt by Molmil](/molmil-images/mine/5lqt) | |
1I39
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![BU of 1i39 by Molmil](/molmil-images/mine/1i39) | RNASE HII FROM ARCHAEOGLOBUS FULGIDUS | Descriptor: | RIBONUCLEASE HII | Authors: | Chapados, B.R, Chai, Q, Hosfield, D.J, Qiu, J, Shen, B, Tainer, J.A. | Deposit date: | 2001-02-13 | Release date: | 2001-04-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication. J.Mol.Biol., 307, 2001
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1I3A
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![BU of 1i3a by Molmil](/molmil-images/mine/1i3a) | RNASE HII FROM ARCHAEOGLOBUS FULGIDUS WITH COBALT HEXAMMINE CHLORIDE | Descriptor: | COBALT HEXAMMINE(III), RIBONUCLEASE HII | Authors: | Chapados, B.R, Chai, Q, Hosfield, D.J, Qiu, J, Shen, B, Tainer, J.A. | Deposit date: | 2001-02-13 | Release date: | 2001-04-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication. J.Mol.Biol., 307, 2001
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2VMK
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![BU of 2vmk by Molmil](/molmil-images/mine/2vmk) | Crystal Structure of E. coli RNase E Apoprotein - Catalytic Domain | Descriptor: | RIBONUCLEASE E, SULFATE ION, ZINC ION | Authors: | Koslover, D.J, Callaghan, A.J, Marcaida, M.J, Martick, M, Scott, W.G, Luisi, B.F. | Deposit date: | 2008-01-28 | Release date: | 2008-07-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The Crystal Structure of the Escherichia Coli Rnase E Apoprotein and a Mechanism for RNA Degradation. Structure, 16, 2008
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6I0T
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![BU of 6i0t by Molmil](/molmil-images/mine/6i0t) | Crystal structure of DmTailor in complex with GpU | Descriptor: | RNA (5'-R(*GP*U)-3'), Terminal uridylyltransferase Tailor | Authors: | Kroupova, A, Ivascu, A, Jinek, M. | Deposit date: | 2018-10-26 | Release date: | 2018-12-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor. Nucleic Acids Res., 47, 2019
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4OZS
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![BU of 4ozs by Molmil](/molmil-images/mine/4ozs) | RNA binding protein | Descriptor: | Alpha solenoid protein | Authors: | Gully, B.S, Bond, C.S. | Deposit date: | 2014-02-19 | Release date: | 2015-04-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | The design and structural characterization of a synthetic pentatricopeptide repeat protein. Acta Crystallogr.,Sect.D, 71, 2015
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7C06
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![BU of 7c06 by Molmil](/molmil-images/mine/7c06) | Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU. | Descriptor: | RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ... | Authors: | Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. | Deposit date: | 2020-04-30 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1. Nat Commun, 11, 2020
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7C08
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![BU of 7c08 by Molmil](/molmil-images/mine/7c08) | Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU. | Descriptor: | RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ... | Authors: | Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. | Deposit date: | 2020-04-30 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1. Nat Commun, 11, 2020
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6VSX
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![BU of 6vsx by Molmil](/molmil-images/mine/6vsx) | |
6SQN
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7CT8
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![BU of 7ct8 by Molmil](/molmil-images/mine/7ct8) | Crystal structure of apo CmoB from Vibrio Vulnificus | Descriptor: | tRNA U34 carboxymethyltransferase | Authors: | Kim, J, Jeong, S. | Deposit date: | 2020-08-18 | Release date: | 2021-03-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural snapshots of CmoB in various states during wobble uridine modification of tRNA. Biochem.Biophys.Res.Commun., 534, 2021
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2CD1
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4KLB
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![BU of 4klb by Molmil](/molmil-images/mine/4klb) | Crystal Structure of Cruzain in complex with the non-covalent inhibitor Nequimed176 | Descriptor: | 2-{[(1H-1,2,4-triazol-5-ylsulfanyl)acetyl]amino}thiophene-3-carboxamide, Cruzipain | Authors: | Fernandes, W.B, Montanari, C.A, Mckerrow, J.H. | Deposit date: | 2013-05-07 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Non-peptidic Cruzain Inhibitors with Trypanocidal Activity Discovered by Virtual Screening and In Vitro Assay. Plos Negl Trop Dis, 7, 2013
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8PTZ
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![BU of 8ptz by Molmil](/molmil-images/mine/8ptz) | Cryo-EM structure of human Elp123 in complex with tRNA, S-ethyl-CoA, 5'-deoxyadenosine and methionine | Descriptor: | 5'-DEOXYADENOSINE, Elongator complex protein 1, Elongator complex protein 2, ... | Authors: | Abbassi, N, Jaciuk, M, Lin, T.-Y, Glatt, S. | Deposit date: | 2023-07-16 | Release date: | 2024-04-17 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Cryo-EM structures of the human Elongator complex at work. Nat Commun, 15, 2024
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8PU0
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![BU of 8pu0 by Molmil](/molmil-images/mine/8pu0) | Cryo-EM structure of human Elp123 in complex with tRNA, desulpho-CoA, 5'-deoxyadenosine and methionine | Descriptor: | 5'-DEOXYADENOSINE, DESULFO-COENZYME A, Elongator complex protein 1, ... | Authors: | Abbassi, N, Jaciuk, M, Lin, T.-Y, Glatt, S. | Deposit date: | 2023-07-16 | Release date: | 2024-04-17 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.25 Å) | Cite: | Cryo-EM structures of the human Elongator complex at work. Nat Commun, 15, 2024
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