3GWX
 
 | | MOLECULAR RECOGNITION OF FATTY ACIDS BY PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS | | Descriptor: | 5,8,11,14,17-EICOSAPENTAENOIC ACID, PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA)) | | Authors: | Xu, H.E, Lambert, M.H, Montana, V.G, Parks, D.J, Blanchard, S.G, Brown, P.J, Sternbach, D.D, Lehmann, J.M, Wisely, G.B, Willson, T.M, Kliewer, S.A, Milburn, M.V. | | Deposit date: | 1999-04-26 | | Release date: | 2000-04-26 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular recognition of fatty acids by peroxisome proliferator-activated receptors.
Mol.Cell, 3, 1999
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1EUP
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1QB6
 | | BOVINE TRYPSIN 3,3'-[3,5-DIFLUORO-4-METHYL-2, 6-PYRIDINEDIYLBIS(OXY)]BIS(BENZENECARBOXIMIDAMIDE) (ZK-805623) COMPLEX | | Descriptor: | 3,3'-[3,5-DIFLUORO-4-METHYL-2,6-PYRIDYLENEBIS(OXY)]-BIS(BENZENECARBOXIMIDAMIDE), CALCIUM ION, POTASSIUM ION, ... | | Authors: | Whitlow, M. | | Deposit date: | 1999-04-29 | | Release date: | 2000-04-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin.
Acta Crystallogr.,Sect.D, 55, 1999
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1QB1
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1QB0
 | | HUMAN CDC25B CATALYTIC DOMAIN | | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, PROTEIN (M-PHASE INDUCER PHOSPHATASE 2 (CDC25B)), ... | | Authors: | Watenpaugh, K.D, Reynolds, R.A. | | Deposit date: | 1999-04-29 | | Release date: | 2000-04-29 | | Last modified: | 2018-02-28 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle.
J.Mol.Biol., 293, 1999
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1QNY
 | | X-ray refinement of D2O soaked crystal of concanavalin A | | Descriptor: | CALCIUM ION, CONCANAVALIN A, MANGANESE (II) ION | | Authors: | Habash, J, Raftery, J, Nuttall, R, Price, H.J, Lehmann, M.S, Wilkinson, C, Kalb(Gilboa), A.J, Helliwell, J.R. | | Deposit date: | 1999-10-26 | | Release date: | 2000-04-30 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Direct Determination of the Positions of Deuterium Atoms of Bound Water in Concanavalin a by Neutron Laue Crystallography
Acta Crystallogr.,Sect.D, 56, 2000
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1QB9
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1EVV
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1EVO
 | | NMR OBSERVATION OF A NOVEL C-TETRAD | | Descriptor: | DNA (5'-D(*TP*GP*GP*GP*CP*GP*GP*T)-3') | | Authors: | Patel, P.K, Bhavesh, N.S, Hosur, R.V. | | Deposit date: | 2000-04-20 | | Release date: | 2000-05-01 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR observation of a novel C-tetrad in the structure of the SV40 repeat sequence GGGCGG.
Biochem.Biophys.Res.Commun., 270, 2000
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1EOD
 | | CRYSTAL STRUCTURE OF THE N136D MUTANT OF A SHAKER T1 DOMAIN | | Descriptor: | POTASSIUM CHANNEL KV1.1 | | Authors: | Nanao, M.H, Cushman, S.J, Jahng, A.W, DeRubeis, D, Choe, S, Pfaffinger, P.J. | | Deposit date: | 2000-03-22 | | Release date: | 2000-05-02 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Voltage dependent activation of potassium channels is coupled to T1 domain structure.
Nat.Struct.Biol., 7, 2000
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1EOF
 | | CRYSTAL STRUCTURE OF THE N136A MUTANT OF A SHAKER T1 DOMAIN | | Descriptor: | POTASSIUM CHANNEL KV1.1 | | Authors: | Nanao, M.H, Cushman, S.J, Jahng, A.W, DeRubeis, D, Choe, S, Pfaffinger, P.J. | | Deposit date: | 2000-03-22 | | Release date: | 2000-05-02 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Voltage dependent activation of potassium channels is coupled to T1 domain structure.
Nat.Struct.Biol., 7, 2000
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1EM2
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1EOE
 | | CRYSTAL STRUCTURE OF THE V135R MUTANT OF A SHAKER T1 DOMAIN | | Descriptor: | POTASSIUM CHANNEL KV1.1 | | Authors: | Nanao, M.H, Cushman, S.J, Jahng, A.W, DeRubeis, D, Choe, S, Pfaffinger, P.J. | | Deposit date: | 2000-03-22 | | Release date: | 2000-05-02 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.704 Å) | | Cite: | Voltage dependent activation of potassium channels is coupled to T1 domain structure.
Nat.Struct.Biol., 7, 2000
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1DAY
 | | CRYSTAL STRUCTURE OF A BINARY COMPLEX OF PROTEIN KINASE CK2 (ALPHA-SUBUNIT) AND MG-GMPPNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, PROTEIN KINASE CK2 | | Authors: | Niefind, K, Puetter, M, Guerra, B, Issinger, O.G, Schomburg, D. | | Deposit date: | 1999-11-01 | | Release date: | 2000-05-03 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | GTP plus water mimic ATP in the active site of protein kinase CK2.
Nat.Struct.Biol., 6, 1999
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1DAW
 | | CRYSTAL STRUCTURE OF A BINARY COMPLEX OF PROTEIN KINASE CK2 (ALPHA-SUBUNIT) AND MG-AMPPNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN KINASE CK2 | | Authors: | Niefind, K, Puetter, M, Guerra, B, Issinger, O.G, Schomburg, D. | | Deposit date: | 1999-11-01 | | Release date: | 2000-05-03 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | GTP plus water mimic ATP in the active site of protein kinase CK2.
Nat.Struct.Biol., 6, 1999
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1DLK
 | | CRYSTAL STRUCTURE ANALYSIS OF DELTA-CHYMOTRYPSIN BOUND TO A PEPTIDYL CHLOROMETHYL KETONE INHIBITOR | | Descriptor: | CHLORIDE ION, Thrombin heavy chain, Thrombin light chain, ... | | Authors: | Mac Sweeney, A, Birrane, G, Walsh, M.A, O'Connell, T, Malthouse, J.P.G. | | Deposit date: | 1999-12-10 | | Release date: | 2000-05-03 | | Last modified: | 2018-09-12 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Crystal structure of delta-chymotrypsin bound to a peptidyl chloromethyl ketone inhibitor.
Acta Crystallogr.,Sect.D, 56, 2000
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1DAZ
 | | Structural and kinetic analysis of drug resistant mutants of HIV-1 protease | | Descriptor: | HIV-1 PROTEASE (RETROPEPSIN), N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide | | Authors: | Mahalingam, B, Louis, J.M, Reed, C.C, Adomat, J.M, Krouse, J, Wang, Y.F, Harrison, R.W, Weber, I.T. | | Deposit date: | 1999-11-01 | | Release date: | 2000-05-03 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural and kinetic analysis of drug resistant mutants of HIV-1 protease.
Eur.J.Biochem., 263, 1999
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1ENN
 | | SOLVENT ORGANIZATION IN AN OLIGONUCLEOTIDE CRYSTAL: THE STRUCTURE OF D(GCGAATTCG)2 AT ATOMIC RESOLUTION | | Descriptor: | CHLORIDE ION, DNA (5'-D(*GP*CP*GP*AP*AP*TP*TP*CP*G)-3'), MAGNESIUM ION, ... | | Authors: | Soler-Lopez, M, Malinina, L, Subirana, J.A. | | Deposit date: | 2000-03-21 | | Release date: | 2000-05-03 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (0.89 Å) | | Cite: | Solvent organization in an oligonucleotide crystal. The structure of d(GCGAATTCG)2 at atomic resolution.
J.Biol.Chem., 275, 2000
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1EO0
 | | CONSERVED DOMAIN COMMON TO TRANSCRIPTION FACTORS TFIIS, ELONGIN A, CRSP70 | | Descriptor: | TRANSCRIPTION ELONGATION FACTOR S-II | | Authors: | Booth, V, Koth, C, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2000-03-21 | | Release date: | 2000-05-03 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of a conserved domain common to the transcription factors TFIIS, elongin A, and CRSP70
J.Biol.Chem., 275, 2000
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1ESU
 | | S235A MUTANT OF TEM1 BETA-LACTAMASE | | Descriptor: | BETA-LACTAMASE, SULFATE ION | | Authors: | Fonze, E, Charlier, P. | | Deposit date: | 2000-04-11 | | Release date: | 2000-05-03 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | TEM1 beta-lactamase structure solved by molecular replacement and refined structure of the S235A mutant.
Acta Crystallogr.,Sect.D, 51, 1995
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1EV8
 | | CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI | | Descriptor: | THYMIDYLATE SYNTHASE | | Authors: | Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L. | | Deposit date: | 2000-04-19 | | Release date: | 2000-05-03 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Catalytic cysteine of thymidylate synthase is activated upon substrate binding.
Biochemistry, 39, 2000
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1ES4
 | | C98N mutant of streptomyces K15 DD-transpeptidase | | Descriptor: | DD-TRANSPEPTIDASE | | Authors: | Fonze, E, Charlier, P. | | Deposit date: | 2000-04-07 | | Release date: | 2000-05-03 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis.
Biochemistry, 42, 2003
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1EU5
 | | STRUCTURE OF E. COLI DUTPASE AT 1.45 A | | Descriptor: | DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, GLYCEROL | | Authors: | Gonzalez, A, Larsson, G, Persson, R, Cedergren-Zeppezauer, E. | | Deposit date: | 2000-04-13 | | Release date: | 2000-05-03 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Atomic resolution structure of Escherichia coli dUTPase determined ab initio.
Acta Crystallogr.,Sect.D, 57, 2001
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1ERF
 | | CONFORMATIONAL MAPPING OF THE N-TERMINAL FUSION PEPTIDE OF HIV-1 GP41 USING 13C-ENHANCED FOURIER TRANSFORM INFRARED SPECTROSCOPY (FTIR) | | Descriptor: | TRANSMEMBRANE GLYCOPROTEIN | | Authors: | Gordon, L.M, Mobley, P.W, Pilpa, R, Sherman, M.A, Waring, A.J. | | Deposit date: | 2000-04-06 | | Release date: | 2000-05-03 | | Last modified: | 2011-07-13 | | Method: | INFRARED SPECTROSCOPY | | Cite: | Conformational mapping of the N-terminal peptide of HIV-1 gp41 in membrane environments using (13)C-enhanced Fourier transform infrared spectroscopy.
Biochim.Biophys.Acta, 1559, 2002
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1ES5
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