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1CT1
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BU of 1ct1 by Molmil
CHOLERA TOXIN B-PENTAMER MUTANT G33R BOUND TO RECEPTOR PENTASACCHARIDE
Descriptor: CHLORIDE ION, CHOLERA TOXIN, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1997-06-03
Release date:1997-10-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies of receptor binding by cholera toxin mutants.
Protein Sci., 6, 1997
1LTT
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LACTOSE BINDING TO HEAT-LABILE ENTEROTOXIN REVEALED BY X-RAY CRYSTALLOGRAPHY
Descriptor: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B, ...
Authors:Sixma, T.K, Hol, W.G.J.
Deposit date:1992-07-15
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Lactose binding to heat-labile enterotoxin revealed by X-ray crystallography.
Nature, 355, 1992
8QRE
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BU of 8qre by Molmil
Cholera holotoxin (wildtype)
Descriptor: ACETATE ION, Cholera enterotoxin subunit A, Cholera enterotoxin subunit B, ...
Authors:Mojica, N, Cordara, G, Krengel, U.
Deposit date:2023-10-06
Release date:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Using Vibrio natriegens for High-Yield Production of Challenging Expression Targets and for Protein Perdeuteration.
Biochemistry, 63, 2024
1LTG
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BU of 1ltg by Molmil
THE ARG7LYS MUTANT OF HEAT-LABILE ENTEROTOXIN EXHIBITS GREAT FLEXIBILITY OF ACTIVE SITE LOOP 47-56 OF THE A SUBUNIT
Descriptor: HEAT-LABILE ENTEROTOXIN
Authors:Van Den Akker, F, Hol, W.G.J.
Deposit date:1995-06-13
Release date:1995-09-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
Biochemistry, 34, 1995
2XRQ
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BU of 2xrq by Molmil
Crystal structures exploring the origins of the broader specificity of escherichia coli heat-labile enterotoxin compared to cholera toxin
Descriptor: HEAT-LABILE ENTEROTOXIN B CHAIN, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Holmner, A, Mackenzie, A, Okvist, M, Jansson, L, Lebens, M, Teneberg, S, Krengel, U.
Deposit date:2010-09-19
Release date:2010-12-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures Exploring the Origins of the Broader Specificity of Escherichia Coli Heat-Labile Enterotoxin Compared to Cholera Toxin
J.Mol.Biol., 406, 2011
1FGB
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TOXIN
Descriptor: CHOLERA TOXIN B SUBUNIT PENTAMER
Authors:Zhang, R.-G, Westbrook, E.
Deposit date:1996-02-21
Release date:1996-12-23
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The 2.4 A crystal structure of cholera toxin B subunit pentamer: choleragenoid.
J.Mol.Biol., 251, 1995
1XTC
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BU of 1xtc by Molmil
CHOLERA TOXIN
Descriptor: CHOLERA TOXIN
Authors:Zhang, R.-G, Westbrook, E.
Deposit date:1996-01-10
Release date:1996-08-01
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The three-dimensional crystal structure of cholera toxin.
J.Mol.Biol., 251, 1995
6HSV
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BU of 6hsv by Molmil
Engineered higher-order assembly of Cholera Toxin B subunits via the addition of C-terminal parallel coiled-coiled domains
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, PHOSPHATE ION, ...
Authors:Pearson, A.R, Turnbull, W.B, Ross, J.F, Trinh, C.H, Webb, M.E.
Deposit date:2018-10-01
Release date:2019-03-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Directed Assembly of Homopentameric Cholera Toxin B-Subunit Proteins into Higher-Order Structures Using Coiled-Coil Appendages.
J.Am.Chem.Soc., 141, 2019
1S5C
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Cholera holotoxin with an A-subunit Y30S mutation, Crystal form 1
Descriptor: Cholera enterotoxin, A chain, SODIUM ION, ...
Authors:O'Neal, C.J, Amaya, E.I, Jobling, M.G, Holmes, R.K, Hol, W.G.
Deposit date:2004-01-20
Release date:2004-04-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
1HTL
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MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
Descriptor: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1995-02-15
Release date:1995-04-20
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli.
Nat.Struct.Biol., 2, 1995
2O2L
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BU of 2o2l by Molmil
Crystal structure of human heat-labile enterotoxin in complex with a blood group A antigen analog
Descriptor: Heat-labile enterotoxin B chain, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]beta-D-glucopyranose
Authors:Holmner, A, Askarieh, G, Okvist, M, Krengel, U.
Deposit date:2006-11-30
Release date:2007-08-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Blood Group Antigen Recognition by Escherichia coli Heat-labile Enterotoxin
J.Mol.Biol., 371, 2007
1LTB
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BU of 1ltb by Molmil
2.6 ANGSTROMS CRYSTAL STRUCTURE OF PARTIALLY-ACTIVATED E. COLI HEAT-LABILE ENTEROTOXIN (LT)
Descriptor: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B
Authors:Merritt, E.A, Sixma, T.K, Hol, W.G.J.
Deposit date:1993-09-15
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of partially-activated E. coli heat-labile enterotoxin (LT) at 2.6 A resolution.
FEBS Lett., 337, 1994
1S5F
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BU of 1s5f by Molmil
Cholera holotoxin, Crystal form 2
Descriptor: Cholera enterotoxin, A chain, SODIUM ION, ...
Authors:O'Neal, C.J, Amaya, E.I, Jobling, M.G, Holmes, R.K, Hol, W.G.
Deposit date:2004-01-20
Release date:2004-04-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
1LTR
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BU of 1ltr by Molmil
CRYSTAL STRUCTURE OF THE B SUBUNIT OF HUMAN HEAT-LABILE ENTEROTOXIN FROM E. COLI CARRYING A PEPTIDE WITH ANTI-HSV ACTIVITY
Descriptor: HEAT-LABILE ENTEROTOXIN, SULFATE ION
Authors:Matkovic-Calogovic, D, Loreggian, A, Palu, G, Zanotti, G.
Deposit date:1998-07-31
Release date:1999-02-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Crystal structure of the B subunit of Escherichia coli heat-labile enterotoxin carrying peptides with anti-herpes simplex virus type 1 activity.
J.Biol.Chem., 274, 1999
1B44
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BU of 1b44 by Molmil
CRYSTAL STRUCTURE OF THE B SUBUNIT OF HEAT-LABILE ENTEROTOXIN FROM E. COLI CARRYING A PEPTIDE WITH ANTI-HSV ACTIVITY
Descriptor: PROTEIN (B-POL SUBUNIT OF HEAT-LABILE ENTEROTOXIN)
Authors:Matkovic-Calogovic, D, Loregian, A, D'Acunto, M.R, Battistutta, R, Tossi, A, Palu, G, Zanotti, G.
Deposit date:1999-01-04
Release date:1999-01-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of the B subunit of Escherichia coli heat-labile enterotoxin carrying peptides with anti-herpes simplex virus type 1 activity.
J.Biol.Chem., 274, 1999
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