2O2L

Crystal structure of human heat-labile enterotoxin in complex with a blood group A antigen analog

Summary for 2O2L

• Entry DOI: 10.2210/pdb2o2l/pdb
• Related: 2NZG
• Descriptor: Heat-labile enterotoxin B chain, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]beta-D-glucopyranose (3 entities in total)
• Functional Keywords: enterotoxigenic e. coli, heat-labile enterotoxin, blood group antigen, toxin
• Biological source: Escherichia coli
• Total number of polymer chains: 10
• Total formula weight: 125692.11

Authors

Holmner, A.,Askarieh, G.,Okvist, M.,Krengel, U. (deposition date: 2006-11-30, release date: 2007-08-14, Last modification date: 2023-10-25)

• Primary citation: Holmner, A.,Askarieh, G.,Okvist, M.,Krengel, U.; Blood Group Antigen Recognition by Escherichia coli Heat-labile Enterotoxin; J.Mol.Biol., 371:754-764, 2007; PubMed: 17586525; DOI: 10.1016/j.jmb.2007.05.064

Experimental method

X-RAY DIFFRACTION (2.53 Å)