PDB: 222415 resultsInfo pagesStatus searchChemie searchBIRD

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4FO8	Pseudomonas aeruginosa MetAP with Met, in Mn form Descriptor: MANGANESE (II) ION, METHIONINE, Methionine aminopeptidase Authors: Ye, Q.Z, Lu, J.P. Deposit date: 2012-06-20 Release date: 2013-07-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Methionine excision captured by the structures of a methionine aminopeptidase To be published
4FQX	Crystal structure of HLA-DM bound to HLA-DR1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ... Authors: Sethi, D.K, Pos, W, Wucherpfennig, K.W. Deposit date: 2012-06-25 Release date: 2013-01-09 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.599 Å) Cite: Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection. Cell(Cambridge,Mass.), 151, 2012
4FP3	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(Furan-2-ylmethyl)ammonio]sulfonate Descriptor: 2-[(furan-2-ylmethyl)amino]ethanesulfonic acid, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.743 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPJ	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Methoxybenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-methoxybenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.981 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FQC	Crystal Structure of PGT121 Fab Bound to a complex-type sialylated N-glycan Descriptor: Fab heavy chain, Fab light chain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Scharf, L, Bjorkman, P.J. Deposit date: 2012-06-25 Release date: 2012-11-14 Last modified: 2021-05-19 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies. Proc.Natl.Acad.Sci.USA, 109, 2012
4FDG	Crystal Structure of an Archaeal MCM Filament Descriptor: Minichromosome maintenance protein MCM, ZINC ION Authors: Slaymaker, I.M, Fu, Y, Brewster, A.B, Chen, X.S. Deposit date: 2012-05-28 Release date: 2013-03-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology. Nucleic Acids Res., 41, 2013
4NTG	Crystal structure of D60A mutant of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with C12 ceramide-1-phosphate (d18:1/12:0) at 2.55 Angstrom resolution Descriptor: (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, accelerated-cell-death 11 Authors: Simanshu, D.K, Brown, R.E, Patel, D.J. Deposit date: 2013-12-02 Release date: 2014-02-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5505 Å) Cite: Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels. Cell Rep, 6, 2014
3GYO	Se-Met Rtt106p Descriptor: Histone chaperone RTT106 Authors: Liu, Y, Huang, H, Shi, Y, Teng, M. Deposit date: 2009-04-04 Release date: 2009-12-08 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural analysis of Rtt106p reveals a DNA-binding role required for heterochromatin silencing J.Biol.Chem., 285, 2010
4NVA	Predicting protein conformational response in prospective ligand discovery Descriptor: Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE Authors: Fischer, M, Fraser, J.S. Deposit date: 2013-12-05 Release date: 2013-12-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery. Nat Chem, 6, 2014
4NVL	Predicting protein conformational response in prospective ligand discovery. Descriptor: 1-(1H-benzimidazol-1-yl)propan-2-one, Cytochrome c peroxidase, PHOSPHATE ION, ... Authors: Fischer, M, Fraser, J.S. Deposit date: 2013-12-05 Release date: 2013-12-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.432 Å) Cite: Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery. Nat Chem, 6, 2014
4O29	PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE from Pyrobaculum aerophilum in COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE Descriptor: Protein-L-isoaspartate O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE Authors: Sawaya, M.R, Yeates, T.O, Griffith, S.C. Deposit date: 2013-12-17 Release date: 2014-01-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of L-isoaspartyl (D-aspartyl) Methyltransferase Thesis, University of California, Los Angeles, 2002
3H0A	Crystal Structure of Peroxisome Proliferator-Activated Receptor Gamma (PPARg) and Retinoic Acid Receptor Alpha (RXRa) in Complex with 9-cis Retinoic Acid, Co-activator Peptide, and a Partial Agonist Descriptor: 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid, Nuclear receptor coactivator 1, Co-activator Peptide, ... Authors: Wang, Z, Sudom, A, Walker, N.P. Deposit date: 2009-04-08 Release date: 2009-06-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma. Bioorg.Med.Chem.Lett., 19, 2009
3H6D	Structure of the mycobacterium tuberculosis DUTPase D28N mutant Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... Authors: Leveles, I, Harmat, V, Nagy, G, Takacs, E, Lopata, A, Toth, J, Vertessy, B.G. Deposit date: 2009-04-23 Release date: 2009-11-24 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases. Febs Lett., 584, 2010
4O3V	Crystal structure of a VirB8-like protein of type IV secretion system from Rickettsia typhi Descriptor: S,R MESO-TARTARIC ACID, VirB8-like protein of type IV secretion system Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-12-18 Release date: 2014-03-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems. MBio, 6, 2015
3UC4	The crystal structure of Snf1-related kinase 2.6 Descriptor: Serine/threonine-protein kinase SRK2E Authors: Zhou, X.E, Ng, L.-M, Soon, F.-F, Kovach, A, Suino-Powell, K.M, Li, J, Melcher, K, Xu, H.E. Deposit date: 2011-10-26 Release date: 2011-12-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases. Proc.Natl.Acad.Sci.USA, 108, 2011
3UCT	Structure of Mn2+-bound N-terminal domain of calmodulin in the presence of Zn2+ Descriptor: Calmodulin, MANGANESE (II) ION, ZINC ION Authors: Senguen, F.T, Grabarek, Z. Deposit date: 2011-10-27 Release date: 2012-08-08 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-ray Structures of Magnesium and Manganese Complexes with the N-Terminal Domain of Calmodulin: Insights into the Mechanism and Specificity of Metal Ion Binding to an EF-Hand. Biochemistry, 51, 2012
3UCL	Cyclohexanone-bound crystal structure of cyclohexanone monooxygenase in the Rotated conformation Descriptor: CYCLOHEXANONE, Cyclohexanone monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, ... Authors: Yachnin, B.J, Berghuis, A.M. Deposit date: 2011-10-27 Release date: 2012-04-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.36 Å) Cite: The Substrate-Bound Crystal Structure of a Baeyer-Villiger Monooxygenase Exhibits a Criegee-like Conformation. J.Am.Chem.Soc., 134, 2012
3UIB	Map kinase LMAMPK10 from leishmania major in complex with SB203580 Descriptor: 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, mitogen-activated protein kinase Authors: Horjales, S, Schmidt-Arras, D, Leclercq, O, Spath, G, Buschiazzo, A. Deposit date: 2011-11-04 Release date: 2012-09-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.65 Å) Cite: The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms. Structure, 20, 2012
4NVH	Predicting protein conformational response in prospective ligand discovery Descriptor: 3-nitroquinolin-4-amine, Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE Authors: Fischer, M, Fraser, J.S. Deposit date: 2013-12-05 Release date: 2013-12-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.24 Å) Cite: Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery. Nat Chem, 6, 2014
4NWM	Crystal structure of Bruton agammaglobulinemia tyrosine kinase complexed with BMS-809959 aka 4-tert-butyl-n-[2-me thyl-3-(6-{[4-(morpholine-4-carbonyl)phenyl]amino}-9h- purin-2-yl)phenyl]benzamide Descriptor: 4-tert-butyl-N-[2-methyl-3-(6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-7H-purin-2-yl)phenyl]benzamide, Tyrosine-protein kinase BTK Authors: Muckelbauer, J.K. Deposit date: 2013-12-06 Release date: 2014-04-02 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases. Bioorg.Med.Chem.Lett., 24, 2014
4NWX	Crystal structure of phosphoglycerate mutase from Staphylococcus aureus in 2-phosphoglyceric acid bound form Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, 2-PHOSPHOGLYCERIC ACID, ... Authors: Roychowdhury, A, Kundu, A, Bose, M, Gujar, A, Das, A.K. Deposit date: 2013-12-07 Release date: 2015-01-14 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism Febs J., 282, 2015
3UE5	ECP-cleaved Actin in complex with Spir domain D Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... Authors: Chen, C, Phillips, M, Sawaya, M.R, Ralston, C.Y, Quinlan, M.E. Deposit date: 2011-10-28 Release date: 2012-02-15 Last modified: 2012-04-11 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Multiple Forms of Spire-Actin Complexes and their Functional Consequences. J.Biol.Chem., 287, 2012
4O5F	Crystal structure of Type III pantothenate kinase from Burkholderia thailandensis in complex with pantothenate and phosphate Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-12-19 Release date: 2014-01-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal structure of Type III pantothenate kinase from Burkholderia thailandensis in complex with pantothenate and phosphate To be Published
3H5A	Crystal structure of E. coli MccB Descriptor: MccB protein, ZINC ION Authors: Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A. Deposit date: 2009-04-21 Release date: 2009-06-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.8 Å) Cite: How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic. Embo J., 28, 2009
3GLB	Crystal structure of the effector binding domain of a CATM variant (R156H) Descriptor: (2Z,4Z)-HEXA-2,4-DIENEDIOIC ACID, GLYCEROL, HTH-type transcriptional regulator catM, ... Authors: Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C. Deposit date: 2009-03-11 Release date: 2009-05-19 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1. Mol.Microbiol., 72, 2009

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