PDB: 8697 resultsInfo pagesStatus searchChemie searchBIRD

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2E2H	RNA polymerase II elongation complex at 5 mM Mg2+ with GTP Descriptor: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... Authors: Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. Deposit date: 2006-11-14 Release date: 2006-12-12 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.95 Å) Cite: Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
2E2I	RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ... Authors: Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. Deposit date: 2006-11-14 Release date: 2006-12-19 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.41 Å) Cite: Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
3S1R	RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with GTP Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-16 Release date: 2011-08-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3S16	RNA Polymerase II Initiation Complex with an 8-nt RNA Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-14 Release date: 2011-08-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.241 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3S14	RNA Polymerase II Initiation Complex with a 6-nt RNA Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-14 Release date: 2011-08-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3S1N	RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 2) Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*GP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-15 Release date: 2011-08-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3S2D	RNA Polymerase II Initiation Complex with a 5-nt RNA containing a 5Br-U Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*AP*CP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-16 Release date: 2011-08-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3S1Q	RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-16 Release date: 2011-08-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3S15	RNA Polymerase II Initiation Complex with a 7-nt RNA Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-14 Release date: 2011-08-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3S2H	RNA Polymerase II Initiation Complex with a 6-nt RNA containing a 2[prime]-iodo ATP Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-16 Release date: 2011-08-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3RZD	RNA Polymerase II Initiation Complex with a 5-nt RNA Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-11 Release date: 2011-08-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3RZO	RNA Polymerase II Initiation Complex with a 4-nt RNA Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-12 Release date: 2011-08-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3S17	RNA Polymerase II Initiation Complex with a 9-nt RNA Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-14 Release date: 2011-08-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
3S1M	RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 1) Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*GP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. Deposit date: 2011-05-15 Release date: 2011-08-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.13 Å) Cite: Initiation complex structure and promoter proofreading. Science, 333, 2011
6WOX	Thermus thermophilus RNA polymerase initially transcribing complex with 2'dCTP Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*G)-3'), ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2020-04-26 Release date: 2020-06-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.14 Å) Cite: The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases. Nat Commun, 12, 2021
6WOY	Thermus thermophilus RNA polymerase initially transcribing complex with 3'dCTP Descriptor: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*G)-3'), ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2020-04-26 Release date: 2020-06-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3 Å) Cite: The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases. Nat Commun, 12, 2021
7F4G	Structure of RPAP2-bound RNA polymerase II Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Chen, X, Qi, Y, Wang, X, Li, J, Zhao, D, Xu, Y. Deposit date: 2021-06-18 Release date: 2021-07-07 Last modified: 2022-07-20 Method: ELECTRON MICROSCOPY (2.78 Å) Cite: RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex. Cell Rep, 39, 2022
2YU9	RNA polymerase II elongation complex in 150 mm MG+2 with UTP Descriptor: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... Authors: Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. Deposit date: 2007-04-06 Release date: 2007-04-24 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis Cell(Cambridge,Mass.), 127, 2006
2R7Z	Cisplatin lesion containing RNA polymerase II elongation complex Descriptor: 5'-D(*CP*AP*AP*GP*TP*AP*G)-3', 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3', 5'-R(*UP*UP*UP*GP*AP*GP*GP*AP*GP*G)-3', ... Authors: Damsma, G.E, Alt, A, Brueckner, F, Carell, T, Cramer, P. Deposit date: 2007-09-10 Release date: 2007-11-20 Last modified: 2017-10-25 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Mechanism of transcriptional stalling at cisplatin-damaged DNA. Nat.Struct.Mol.Biol., 14, 2007
2NVT	RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP Descriptor: 5'-D(*GP*TP*AP*CP*TP*TP*G)-3', 5'-D(P*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... Authors: Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. Deposit date: 2006-11-13 Release date: 2006-12-12 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.36 Å) Cite: Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
2NVZ	RNA Polymerase II elongation complex with UTP, updated 11/2006 Descriptor: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... Authors: Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. Deposit date: 2006-11-14 Release date: 2006-12-19 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (4.3 Å) Cite: Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
2NVQ	RNA Polymerase II Elongation Complex in 150 mM Mg+2 with 2'dUTP Descriptor: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... Authors: Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. Deposit date: 2006-11-13 Release date: 2006-12-12 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
2NVX	RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP Descriptor: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... Authors: Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. Deposit date: 2006-11-13 Release date: 2006-12-19 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
1HHS	RNA dependent RNA polymerase from dsRNA bacteriophage phi6 Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE Authors: Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. Deposit date: 2000-12-28 Release date: 2001-03-27 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
6F5P	A mechanism for the activation of the influenza virus transcriptase Descriptor: ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, DNA-directed RNA polymerase subunit, MAGNESIUM ION, ... Authors: Serna Martin, I, Grimes, J.M. Deposit date: 2017-12-02 Release date: 2018-09-19 Method: X-RAY DIFFRACTION (4.14 Å) Cite: A Mechanism for the Activation of the Influenza Virus Transcriptase. Mol. Cell, 70, 2018

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