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1JGN
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Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip2
Descriptor: polyadenylate-binding protein 1, polyadenylate-binding protein-interacting protein 2
Authors:Kozlov, G, Siddiqui, N, Coillet-Matillon, S, Ekiel, I, Gehring, K.
Deposit date:2001-06-26
Release date:2003-06-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase
EMBO J., 23, 2004
1JI9
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Solution structure of the alpha-domain of mouse metallothionein-3
Descriptor: CADMIUM ION, METALLOTHIONEIN-III
Authors:Oz, G, Zangger, K, Armitage, I.M.
Deposit date:2001-07-01
Release date:2001-10-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Three-dimensional structure and dynamics of a brain specific growth inhibitory factor: metallothionein-3.
Biochemistry, 40, 2001
1JIE
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Crystal structure of bleomycin-binding protein from bleomycin-producing Streptomyces verticillus complexed with metal-free bleomycin
Descriptor: BLEOMYCIN A2, bleomycin-binding protein
Authors:Sugiyama, M, Kumagai, T, Hayashida, M, Maruyama, M, Matoba, Y.
Deposit date:2001-07-02
Release date:2002-02-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The 1.6-A crystal structure of the copper(II)-bound bleomycin complexed with the bleomycin-binding protein from bleomycin-producing Streptomyces verticillus.
J.Biol.Chem., 277, 2002
6P9K
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Crystal structure of Mycobacterium tuberculosis KasA in complex with O6G
Descriptor: 3-oxoacyl-ACP synthase, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2019-06-10
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
Cell Chem Biol, 27, 2020
1JP7
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Crystal Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase
Descriptor: 5'-deoxy-5'-methylthioadenosine phosphorylase, SULFATE ION
Authors:Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E.
Deposit date:2001-08-01
Release date:2001-10-26
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus.
J.Biol.Chem., 276, 2001
6P9Q
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E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 2
Descriptor: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
Authors:Ma, X, Shia, S, Ornelas, E.
Deposit date:2019-06-10
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
J.Am.Chem.Soc., 142, 2020
1JPJ
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GMPPNP Complex of SRP GTPase NG Domain
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SIGNAL RECOGNITION PARTICLE PROTEIN
Authors:Padmanabhan, S, Freymann, D.M.
Deposit date:2001-08-02
Release date:2002-02-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The conformation of bound GMPPNP suggests a mechanism for gating the active site of the SRP GTPase.
Structure, 9, 2001
1JPR
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Mn substituted Ribonucleotide reductase R2 from E. coli oxidized by nitric oxide
Descriptor: MANGANESE (II) ION, MERCURY (II) ION, Protein R2 of Ribonucleotide reductase
Authors:Hogbom, M, Andersson, M.E, Nordlund, P.
Deposit date:2001-08-03
Release date:2001-08-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structures of oxidized dinuclear manganese centres in Mn-substituted class I ribonucleotide reductase from Escherichia coli: carboxylate shifts with implications for O2 activation and radical generation.
J.Biol.Inorg.Chem., 6, 2001
6CCO
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Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 3-((1S,2S)-2-(4-hydroxy-1H-benzo[d]imidazol-2-yl)cyclopentyl)benzoic acid
Descriptor: 3-[(1S,2S)-2-(7-hydroxy-1H-benzimidazol-2-yl)cyclopentyl]benzoic acid, Phosphopantetheine adenylyltransferase, SULFATE ION
Authors:Mamo, M, Appleton, B.A.
Deposit date:2018-02-07
Release date:2018-03-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria.
J. Med. Chem., 61, 2018
1JQA
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Bacillus stearothermophilus glycerol dehydrogenase complex with glycerol
Descriptor: GLYCEROL, Glycerol Dehydrogenase, ZINC ION
Authors:Ruzheinikov, S.N, Burke, J, Sedelnikova, S, Baker, P.J, Taylor, R, Bullough, P.A, Muir, N.M, Gore, M.G, Rice, D.W.
Deposit date:2001-08-04
Release date:2001-10-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Glycerol dehydrogenase. structure, specificity, and mechanism of a family III polyol dehydrogenase.
Structure, 9, 2001
1JIO
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P450eryF/6DEB
Descriptor: 6-DEOXYERYTHRONOLIDE B, CYTOCHROME P450 107A1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Cupp-Vickery, J.R, Garcia, C, Hofacre, A, McGee-Estrada, K.
Deposit date:2001-07-02
Release date:2001-10-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF.
J.Mol.Biol., 311, 2001
1JJ7
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Crystal Structure of the C-terminal ATPase domain of human TAP1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PEPTIDE TRANSPORTER TAP1
Authors:Gaudet, R, Wiley, D.C.
Deposit date:2001-07-03
Release date:2001-09-12
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing.
EMBO J., 20, 2001
1JJI
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The Crystal Structure of a Hyper-thermophilic Carboxylesterase from the Archaeon Archaeoglobus fulgidus
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Carboxylesterase
Authors:De Simone, G, Menchise, V, Manco, G, Mandrich, L, Sorrentino, N, Lang, D, Rossi, M, Pedone, C.
Deposit date:2001-07-06
Release date:2001-12-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus.
J.Mol.Biol., 314, 2001
8UOA
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Structure of the synaptic vesicle protein 2A Luminal domain in complex with a nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody, Synaptic vesicle glycoprotein 2A, ...
Authors:Mittal, A, Martin, M.F, Levin, E, Adams, C, Yang, M, Ledecq, M, Horanyi, P.S, Coleman, J.A.
Deposit date:2023-10-19
Release date:2024-05-22
Last modified:2024-12-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of synaptic vesicle protein 2A and 2B bound to anticonvulsants.
Nat.Struct.Mol.Biol., 31, 2024
1JQL
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Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III: Structure of beta-delta (1-140)
Descriptor: DNA Polymerase III, BETA CHAIN, DELTA SUBUNIT
Authors:Jeruzalmi, D, Yurieva, O, Zhao, Y, Young, M, Stewart, J, Hingorani, M, O'Donnell, M, Kuriyan, J.
Deposit date:2001-08-07
Release date:2001-09-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 106, 2001
6CDG
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GID4 fragment in complex with a peptide
Descriptor: Glucose-induced degradation protein 4 homolog, Hexapeptide PGLWKS, UNKNOWN ATOM OR ION
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-08
Release date:2018-03-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
4D63
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Structure of the carboxy-terminal domain of the turkey type 3 siadenovirus fibre, avirulent form complexed with 6-sialyllactose.
Descriptor: FIBER KNOB DOMAIN, N-acetyl-alpha-neuraminic acid
Authors:Singh, A.K, van Raaij, M.J.
Deposit date:2014-11-08
Release date:2015-10-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Sialyllactose Binding of the Carboxy-Terminal Head Domain of the Fibre from a Siadenovirus, Turkey Adenovirus 3.
PLoS ONE, 10, 2015
1JQV
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The K213E mutant of Lactococcus lactis Dihydroorotate dehydrogenase A
Descriptor: ACETIC ACID, Dihydroorotate dehydrogenase A, FLAVIN MONONUCLEOTIDE, ...
Authors:Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
Deposit date:2001-08-09
Release date:2003-09-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
1JRB
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The P56A mutant of Lactococcus lactis dihydroorotate dehydrogenase A
Descriptor: FLAVIN MONONUCLEOTIDE, OROTIC ACID, dihydroorotate dehydrogenase A
Authors:Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
Deposit date:2001-08-13
Release date:2003-09-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
1JRM
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NMR structure of MTH0637. Ontario Centre for Structural Proteomics target MTH0637_1_104; Northeast Structural Genomics Target TT135
Descriptor: CONSERVED HYPOTHETICAL PROTEIN mth637
Authors:Pineda-Lucena, A, Northeast Structural Genomics Consortium (NESG)
Deposit date:2001-08-14
Release date:2002-02-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:An NMR approach to structural proteomics.
Proc.Natl.Acad.Sci.USA, 99, 2002
1JK6
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UNCOMPLEXED DES 1-6 BOVINE NEUROPHYSIN
Descriptor: NEUROPHYSIN 2
Authors:Rose, J.P, Wang, B.-C.
Deposit date:2001-07-11
Release date:2003-04-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of an Unliganded Neurophysin and its Vasopressin Complex: Implications for Binding and Allosteric Mechanisms
Protein Sci., 10, 2003
6CQG
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YycF Effector Domain Structure without DNA bound
Descriptor: DNA-binding response regulator, ZINC ION
Authors:Riboldi-Tunnicliffe, A, Gabrielsen, M, Williamson, R.M, Panjikar, S.
Deposit date:2018-03-15
Release date:2019-06-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.932 Å)
Cite:YycF Effector Domain Structure without DNA bound
To Be Published
1JKE
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D-Tyr tRNATyr deacylase from Escherichia coli
Descriptor: D-Tyr-tRNATyr deacylase, ZINC ION
Authors:Ferri-Fioni, M.L, Schmitt, E, Soutourina, J, Plateau, P, Mechulam, Y, Blanquet, S.
Deposit date:2001-07-12
Release date:2002-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of crystalline D-Tyr-tRNA(Tyr) deacylase. A representative of a new class of tRNA-dependent hydrolases.
J.Biol.Chem., 276, 2001
1JL1
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D10A E. coli ribonuclease HI
Descriptor: RIBONUCLEASE HI
Authors:Goedken, E.R, Marqusee, S.
Deposit date:2001-07-13
Release date:2002-02-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Native-state energetics of a thermostabilized variant of ribonuclease HI.
J.Mol.Biol., 314, 2001
6CE2
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Crystal structure of Myotoxin I (MjTX-I) from Bothrops moojeni complexed to inhibitor suramin
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Basic phospholipase A2 homolog 1
Authors:Salvador, G.H.M, Fontes, M.R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism.
Sci Rep, 8, 2018

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