4ARN
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![BU of 4arn by Molmil](/molmil-images/mine/4arn) | Crystal structure of the N-terminal domain of Drosophila Toll receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MALONATE ION, ... | Authors: | Gangloff, M, Gay, N.J. | Deposit date: | 2012-04-25 | Release date: | 2013-01-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor. Structure, 21, 2013
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4B1C
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![BU of 4b1c by Molmil](/molmil-images/mine/4b1c) | New Aminoimidazoles as BACE-1 Inhibitors: From Rational Design to Ab- lowering in Brain | Descriptor: | (2R)-2-cyclopropyl-5-methyl-2-[3-(5-prop-1-yn-1-ylpyridin-3-yl)phenyl]-2H-imidazol-4-amine, BETA-SECRETASE 1, DIMETHYL SULFOXIDE | Authors: | Rahm, F, Blid, J, Ginman, T, Karlstrom, S, Kihlstrom, J, Kolmodin, K, Lindstrom, J, von Berg, S, von Kieseritzky, F, Slivo, C, Swahn, B, Viklund, J, Olsson, L, Johansson, P, Eketjall, S, Falting, J, Jeppsson, F, Stromberg, K, Janson, J, Gravenfors, Y. | Deposit date: | 2012-07-10 | Release date: | 2012-10-10 | Last modified: | 2018-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | New aminoimidazoles as beta-secretase (BACE-1) inhibitors showing amyloid-beta (A beta ) lowering in brain. J. Med. Chem., 55, 2012
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4B1D
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![BU of 4b1d by Molmil](/molmil-images/mine/4b1d) | New Aminoimidazoles as BACE-1 Inhibitors: From Rational Design to Ab- lowering in Brain | Descriptor: | (2S)-2-(4-methoxy-3,5-dimethylphenyl)-5-methyl-2-(3-pyrimidin-5-ylphenyl)-2H-imidazol-4-amine, ACETATE ION, BETA-SECRETASE 1 | Authors: | Rahm, F, Blid, J, Ginman, T, Karlstrom, S, Kihlstrom, J, Kolmodin, K, Lindstrom, J, von Berg, S, von Kieseritzky, F, Slivo, C, Swahn, B, Viklund, J, Olsson, L, Johansson, P, Eketjall, S, Falting, J, Jeppsson, F, Stromberg, K, Janson, J, Gravenfors, Y. | Deposit date: | 2012-07-10 | Release date: | 2012-10-10 | Last modified: | 2018-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | New aminoimidazoles as beta-secretase (BACE-1) inhibitors showing amyloid-beta (A beta ) lowering in brain. J. Med. Chem., 55, 2012
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1OW3
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![BU of 1ow3 by Molmil](/molmil-images/mine/1ow3) | Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho-GTPase-activating protein 1, ... | Authors: | Graham, D.L, Lowe, P.N, Grime, G.W, Marsh, M, Rittinger, K, Smerdon, S.J, Gamblin, S.J, Eccleston, J.F. | Deposit date: | 2003-03-28 | Release date: | 2003-05-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer Chem.Biol., 9, 2002
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1TLF
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![BU of 1tlf by Molmil](/molmil-images/mine/1tlf) | |
1Q90
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![BU of 1q90 by Molmil](/molmil-images/mine/1q90) | Structure of the cytochrome b6f (plastohydroquinone : plastocyanin oxidoreductase) from Chlamydomonas reinhardtii | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 8-HYDROXY-5,7-DIMETHOXY-3-METHYL-2-TRIDECYL-4H-CHROMEN-4-ONE, ... | Authors: | Stroebel, D, Choquet, Y, Popot, J.-L, Picot, D. | Deposit date: | 2003-08-22 | Release date: | 2003-12-09 | Last modified: | 2021-03-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | An Atypical Haem in the Cytochrome B6F Complex Nature, 426, 2003
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1JB0
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![BU of 1jb0 by Molmil](/molmil-images/mine/1jb0) | Crystal Structure of Photosystem I: a Photosynthetic Reaction Center and Core Antenna System from Cyanobacteria | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | Authors: | Jordan, P, Fromme, P, Witt, H.T, Klukas, O, Saenger, W, Krauss, N. | Deposit date: | 2001-06-01 | Release date: | 2001-08-01 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Three-dimensional Structure of Cyanobacterial Photosystem I at 2.5 A Resolution NATURE, 411, 2001
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1XGM
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![BU of 1xgm by Molmil](/molmil-images/mine/1xgm) | |
1XGN
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![BU of 1xgn by Molmil](/molmil-images/mine/1xgn) | |
1XGO
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![BU of 1xgo by Molmil](/molmil-images/mine/1xgo) | |
1LPV
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![BU of 1lpv by Molmil](/molmil-images/mine/1lpv) | DROSOPHILA MELANOGASTER DOUBLESEX (DSX), NMR, 18 STRUCTURES | Descriptor: | Doublesex protein, ZINC ION | Authors: | Zhu, L, Wilken, J, Phillips, N, Narendra, U, Chan, G, Stratton, S, Kent, S, Weiss, M.A. | Deposit date: | 2002-05-08 | Release date: | 2002-10-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers. Genes Dev., 14, 2000
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3CVU
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![BU of 3cvu by Molmil](/molmil-images/mine/3cvu) | Drosophila melanogaster (6-4) photolyase bound to ds DNA with a T-T (6-4) photolesion | Descriptor: | DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T. | Deposit date: | 2008-04-20 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure and mechanism of a DNA (6-4) photolyase. Angew.Chem.Int.Ed.Engl., 47, 2008
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3CVW
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![BU of 3cvw by Molmil](/molmil-images/mine/3cvw) | Drosophila melanogaster (6-4) photolyase H365N mutant bound to ds DNA with a T-T (6-4) photolesion and cofactor F0 | Descriptor: | 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), ... | Authors: | Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T. | Deposit date: | 2008-04-20 | Release date: | 2009-10-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and mechanism of a cofactor f0
accelerated (6-4) photolyase from the fruit fly To be Published
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3CVX
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![BU of 3cvx by Molmil](/molmil-images/mine/3cvx) | Drosophila melanogaster (6-4) photolyase H369M mutant bound to ds DNA with a T-T (6-4) photolesion | Descriptor: | DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T. | Deposit date: | 2008-04-20 | Release date: | 2009-10-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and mechanism of a coenzyme F0
accelerated (6-4) photolyase from the fruit fly To be Published
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3CVY
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![BU of 3cvy by Molmil](/molmil-images/mine/3cvy) | Drosophila melanogaster (6-4) photolyase bound to repaired ds DNA | Descriptor: | DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T. | Deposit date: | 2008-04-20 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure and mechanism of a DNA (6-4) photolyase. Angew.Chem.Int.Ed.Engl., 47, 2008
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1MIJ
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![BU of 1mij by Molmil](/molmil-images/mine/1mij) | |
1XGS
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![BU of 1xgs by Molmil](/molmil-images/mine/1xgs) | |
1SS9
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![BU of 1ss9 by Molmil](/molmil-images/mine/1ss9) | Crystal Structural Analysis of Active Site Mutant Q189E of LgtC | Descriptor: | MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUOROGALACTOSE, alpha-1,4-galactosyl transferase | Authors: | Lairson, L.L, Chiu, C.P, Ly, H.D, He, S, Wakarchuk, W.W, Strynadka, N.C, Withers, S.G. | Deposit date: | 2004-03-23 | Release date: | 2004-09-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Intermediate trapping on a mutant retaining alpha-galactosyltransferase identifies an unexpected aspartate residue. J.Biol.Chem., 279, 2004
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1QRY
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![BU of 1qry by Molmil](/molmil-images/mine/1qry) | Homeobox protein VND (ventral nervous system defective protein) | Descriptor: | PROTEIN (HOMEOBOX VENTRAL NERVOUS SYSTEM DEFECTIVE PROTEIN) | Authors: | Xiang, B. | Deposit date: | 1999-06-16 | Release date: | 1999-07-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Distortion of the three-dimensional structure of the vnd/NK-2 homeodomain bound to DNA induced by an embryonically lethal A35T point mutation. Biochemistry, 42, 2003
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1HKS
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![BU of 1hks by Molmil](/molmil-images/mine/1hks) | SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR | Descriptor: | HEAT-SHOCK TRANSCRIPTION FACTOR | Authors: | Vuister, G.W, Kim, S.-J, Orosz, A, Marquardt, J.L, Wu, C, Bax, A. | Deposit date: | 1994-07-18 | Release date: | 1994-09-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the DNA-binding domain of Drosophila heat shock transcription factor. Nat.Struct.Biol., 1, 1994
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1HKT
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![BU of 1hkt by Molmil](/molmil-images/mine/1hkt) | SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR | Descriptor: | HEAT-SHOCK TRANSCRIPTION FACTOR | Authors: | Vuister, G.W, Kim, S.-J, Orosz, A, Marquardt, J.L, Wu, C, Bax, A. | Deposit date: | 1994-07-18 | Release date: | 1994-09-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the DNA-binding domain of Drosophila heat shock transcription factor. Nat.Struct.Biol., 1, 1994
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1KQQ
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![BU of 1kqq by Molmil](/molmil-images/mine/1kqq) | Solution Structure of the Dead ringer ARID-DNA Complex | Descriptor: | 5'-D(*CP*CP*AP*CP*AP*TP*CP*AP*AP*TP*AP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*TP*AP*TP*TP*GP*AP*TP*GP*TP*GP*G)-3', DEAD RINGER PROTEIN | Authors: | Iwahara, J, Iwahara, M, Daughdrill, G.W, Ford, J, Clubb, R.T. | Deposit date: | 2002-01-07 | Release date: | 2002-03-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of the Dead ringer-DNA complex reveals how AT-rich interaction domains (ARIDs) recognize DNA. EMBO J., 21, 2002
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1M0U
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![BU of 1m0u by Molmil](/molmil-images/mine/1m0u) | Crystal Structure of the Drosophila Glutathione S-transferase-2 in Complex with Glutathione | Descriptor: | GLUTATHIONE, GST2 gene product, SULFATE ION | Authors: | Agianian, B, Tucker, P.A, Schouten, A, Leonard, K, Bullard, B, Gros, P. | Deposit date: | 2002-06-14 | Release date: | 2003-02-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of a Drosophila Sigma Class Glutathione S-transferase Reveals a Novel
Active Site Topography Suited for Lipid Peroxidation Products J.Mol.Biol., 326, 2003
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2K3K
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![BU of 2k3k by Molmil](/molmil-images/mine/2k3k) | |
2JYZ
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![BU of 2jyz by Molmil](/molmil-images/mine/2jyz) | CG7054 solution structure | Descriptor: | CG7054-PA | Authors: | Rautureau, G, Jouvensal, L, Vovelle, F, Schoentgen, F, Locker, D, Decoville, M, Damblon, C. | Deposit date: | 2007-12-21 | Release date: | 2008-12-23 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR structure of a phosphatidyl-ethanolamine binding protein from Drosophila Proteins, 78, 2009
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